{"id":368609,"date":"2025-08-24T01:36:12","date_gmt":"2025-08-24T01:36:12","guid":{"rendered":"https:\/\/www.europesays.com\/uk\/368609\/"},"modified":"2025-08-24T01:36:12","modified_gmt":"2025-08-24T01:36:12","slug":"dna-test-reveals-which-children-are-at-higher-risk-of-obesity-in-adulthood","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/uk\/368609\/","title":{"rendered":"DNA test reveals which children are at higher risk of obesity in adulthood"},"content":{"rendered":"<p><img decoding=\"async\" alt=\"\" class=\"attachment-full\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2025\/08\/girl-with-dad-at-doctor-office.jpg\"\/><\/p>\n<p>A <a href=\"https:\/\/www.foxnews.com\/category\/genetics\" target=\"_blank\" rel=\"noopener noreferrer\">genetic test<\/a> could predict whether a child will be obese as an adult.<\/p>\n<p>A global study, published in the journal Nature Medicine, found that the risk of <a href=\"https:\/\/www.foxnews.com\/category\/health\/nutrition-and-fitness\/obesity\" target=\"_blank\" rel=\"noopener noreferrer\">severe obesity<\/a> in adulthood can be identified in early childhood through a polygenic risk score (PGS).<\/p>\n<p>The PGS acts as a \u201ccalculator\u201d that combines the impact of different genetic risk variants that a person can carry, according to researchers.<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/health\/your-dna-could-stopping-you-from-losing-weight-new-study-suggests\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>YOUR DNA COULD BE STOPPING YOU FROM LOSING WEIGHT, NEW STUDY SUGGESTS<\/strong><\/a><\/p>\n<p>The test can be performed on children before their weight begins to shift, as early as age 5, according to a press release from the University of Copenhagen\u2019s Novo\u202fNordisk Foundation Center for Basic Metabolic Research (CBMR).<\/p>\n<p>The researchers suggest that this may support early prevention strategies for obesity, like <a href=\"https:\/\/www.foxnews.com\/category\/health\/healthy-living\" target=\"_blank\" rel=\"noopener noreferrer\">lifestyle interventions<\/a> at a younger age.<\/p>\n<p>\u201cOverall, these data show that PGSs have the potential to improve obesity prediction, particularly when implemented early in life,\u201d the researchers concluded in the study.<\/p>\n<p>Lead study author Roelof Smit, assistant professor at the NNF Center, wrote in a press release statement that the score is \u201cso powerful\u201d due to its ability to predict adult obesity \u201cwell before other risk factors start to shape their weight later in childhood.\u201d<\/p>\n<p>\u201cIntervening at this point can have a huge impact,\u201d he commented.<\/p>\n<p>The major study was an international collaboration of human <a href=\"https:\/\/www.foxnews.com\/category\/genetics\" target=\"_blank\" rel=\"noopener noreferrer\">genetics researchers<\/a>, consisting of more than 600 scientists from 500 global institutions, as well as the consumer genetics and research company 23andMe, Inc.<\/p>\n<p>After gathering genetic data from more than five million people, the scientists created what\u2019s described as the largest and most diverse <a href=\"https:\/\/www.foxnews.com\/category\/health\/medical-research\" target=\"_blank\" rel=\"noopener noreferrer\">genetic dataset<\/a> in reported history, using that to create the PGS.<\/p>\n<p>The results showed that the PGS was twice as effective as the previous best test in predicting obesity risk, accounting for approximately 17.6% of a child\u2019s risk of developing a high BMI (body mass index) as an adult.<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/newsletters?cmpid=fnfirstnl\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER<\/strong><\/a><\/p>\n<p>\u201cThis new polygenic score is a dramatic improvement in predictive power and a leap forward in the genetic prediction of obesity risk, which brings us much closer to clinically useful genetic testing,\u201d study co-author Ruth Loos, a professor from CBMR at the University of Copenhagen, said in a statement.<\/p>\n<p>The scientists also discovered that those with a higher genetic risk of obesity were more responsive to <a href=\"https:\/\/www.foxnews.com\/category\/health\/nutrition-and-fitness\/weight-loss\" target=\"_blank\" rel=\"noopener noreferrer\">lifestyle weight-loss<\/a> interventions.<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/health\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>For more Health articles, visit\u00a0foxnews.com\/health<\/strong><\/a><\/p>\n<p>These individuals also gained weight back more quickly once the interventions ended.<\/p>\n<p>The researchers noted that the new PGS has its limitations, as it was \u201cfar better at predicting obesity\u201d in those who have a European-like ancestry than in those with African ancestry.<\/p>\n<p style=\"display: inline;\">.<\/p>\n","protected":false},"excerpt":{"rendered":"A genetic test could predict whether a child will be obese as an adult. A global study, published&hellip;\n","protected":false},"author":2,"featured_media":368610,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3846],"tags":[267,70,16,15],"class_list":{"0":"post-368609","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-genetics","8":"tag-genetics","9":"tag-science","10":"tag-uk","11":"tag-united-kingdom"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@uk\/115081184752434260","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/368609","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/comments?post=368609"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/368609\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media\/368610"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media?parent=368609"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/categories?post=368609"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/tags?post=368609"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}