{"id":61628,"date":"2025-04-30T01:06:09","date_gmt":"2025-04-30T01:06:09","guid":{"rendered":"https:\/\/www.europesays.com\/uk\/61628\/"},"modified":"2025-04-30T01:06:09","modified_gmt":"2025-04-30T01:06:09","slug":"ozempic-feet-mouth-among-unusual-glp-1-side-effects","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/uk\/61628\/","title":{"rendered":"Ozempic Feet, Mouth Among Unusual GLP-1 Side Effects"},"content":{"rendered":"<p><img decoding=\"async\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2025\/04\/ozempic-foot-1296x728-header.jpg\" alt=\"Bare feet dangling over water\" class=\"css-1jytyml\"\/><a class=\"icon-hl-pinterest css-1dn5h5\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" data-event=\"Any Page|Image Pinterest Click|Icon Clicked\" data-element-event=\"OPEN|CONTENTBLOCK|Any Page|Article Body|BUTTON|Image Widget Pinterest Click|\" href=\"https:\/\/www.pinterest.com\/pin\/create\/button\/?url=https%3A%2F%2Fwww.healthline.com%2Fhealth-news%2Fozempic-mouth-feet-unusual-side-effects-glp-1-drugs&amp;media=https%3A%2F%2Fmedia.post.rvohealth.io%2Fwp-content%2Fuploads%2F2025%2F04%2Fozempic-foot-1296x728-header.jpg&amp;description=Weight%20Loss%3A%20Ozempic%20Feet%2C%20Mouth%20Among%20Unusual%20GLP-1%20Side%20Effects\" title=\"Share on Pinterest\" data-pin-custom=\"true\" data-share-url=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2025\/04\/ozempic-foot-1296x728-header.jpg\">Share on Pinterest<\/a>Recent anecdotal reports have highlighted strange side effects of GLP-1 medications used for weight loss like \u201cOzempic mouth\u201d and \u201cOzempic feet.\u201d Elena Popova\/Getty Images<\/p>\n<ul>\n<li><strong>\u201cOzempic feet\u201d and \u201cOzempic mouth\u201d are the latest reported cosmetic side effects from GLP-1 medications used for weight loss.<\/strong><\/li>\n<li><strong>Experts say wrinkles and sagging skin can result from rapid weight loss due to<\/strong><strong> loss of fat and muscle mass in certain areas of the body.<\/strong><\/li>\n<li><strong>You can minimize some of these effects by increasing protein in your diet and incorporating resistance training into your exercise routine.<\/strong><\/li>\n<\/ul>\n<p>You can add \u201cOzempic feet\u201d and \u201cOzempic mouth\u201d to the growing list of nicknames for strange and unusual side effects from popular GLP-1 medications used for weight loss.<\/p>\n<p>Reports on social media and elsewhere have been highlighting \u201c<a href=\"https:\/\/nypost.com\/2025\/04\/20\/health\/ozempic-feet-gnarly-side-effect-of-weight-loss-drug-exhibited-by-some-celebs-report\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1c2ok3c\">Ozempic feet<\/a>,\u201d a GLP-1 side effect resulting in excessively wrinkled feet. A recent <a href=\"https:\/\/www.instagram.com\/p\/DIE_qTJzHcz\/?igsh=bHdmdmthd3lpaHE5\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1c2ok3c\">photo<\/a> of a barefoot Sharon Osbourne posted on Instagram set off a flurry of publicity.<\/p>\n<p>Meanwhile, \u201c<a href=\"https:\/\/www.healthline.com\/health-news\/ozempic-face-what-is-it-and-what-can-you-do-about-it\" target=\"_blank\" rel=\"noreferrer noopener\" class=\"content-link css-1c2ok3c\">Ozempic face<\/a>\u201d describes the general hollowing of the face and an increase of wrinkles as people lose weight. There\u2019s also the \u201c<a href=\"https:\/\/www.healthline.com\/health-news\/ozempic-what-to-know-about-this-side-effect-you-may-experience-while-taking-weight-loss-drugs#What-Is-Ozempic-Butt\" target=\"_blank\" rel=\"noreferrer noopener\" class=\"content-link css-1c2ok3c\">Ozempic butt<\/a>\u201d phenomenon, which occurs when sagging skin becomes pronounced around the buttocks as a person loses weight.<\/p>\n<p>While the drug Ozempic is most often pegged to these nicknames, the side effects can also be present with other injectable weight loss medications such as Wegovy, Zepbound, and Mounjaro.<\/p>\n<p>Experts say the side effects aren\u2019t a result of the medications themselves, but rather, are byproducts of rapid weight loss. They also note that these side effects are cosmetic and usually not a danger to a person\u2019s health.<\/p>\n<p>Still, these effects can be minimized through modifications in diet and <a href=\"https:\/\/www.healthline.com\/nutrition\/best-exercise-for-weight-loss\" class=\"content-link css-1c2ok3c\" target=\"_blank\" rel=\"noopener\">exercise<\/a>. People could also try to lose weight at a slower pace to help reduce some of these effects.<\/p>\n<p>\u201cYou need a team to follow you and help you,\u201d said <a href=\"https:\/\/profiles.stanford.edu\/Dan%20Azagury\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1c2ok3c\">Dan Azagury<\/a>, MD, FACS, an associate professor of surgery and the section chief of Minimally Invasive and Bariatric Surgery at Stanford University.<\/p>\n<p>\u201cGet some support and do this in the right way,\u201d he told Healthline. \u201cThis is not a sprint. Slow and steady wins this race.\u201d<\/p>\n<p>Experts say wrinkles and sagging skin may sometimes occur after weight loss because of the loss of fat and the reduction in muscle mass throughout the body.<\/p>\n<p>\u201cAny kind of significant weight loss can have a dramatic change in body habitus and appearance,\u201d said <a href=\"https:\/\/www.memorialcare.org\/providers\/mir-b-ali\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1c2ok3c\">Mir Ali<\/a>, MD, a general surgeon, bariatric surgeon, and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in California.<\/p>\n<p>\u201cWe see the same kind of changes after surgical weight loss as well, so it is more an effect of weight loss, rather than directly because of the medication,\u201d he told Healthline.<\/p>\n<p><a href=\"https:\/\/www.nidhi.me\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1c2ok3c\">Nidhi Pandya<\/a>, an Ayurvedic doctor, holistic practitioner, and author of the book \u201c<a href=\"https:\/\/www.penguinrandomhouse.com\/books\/773404\/your-body-already-knows-by-nidhi-pandya\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1c2ok3c\">Your Body Already Knows<\/a>,\u201d said people should know the benefits and downsides of weight loss medications.<\/p>\n<p>\u201cWhile these drugs are highly effective for lowering appetite and improving glycemic control, they also accelerate weight loss in a way that can have systemic consequences,\u201d Pandya told Healthline.<\/p>\n<p>She lists some of the side effects as:<\/p>\n<ul>\n<li>loss of lean body mass<\/li>\n<li>altered gut microbiome<\/li>\n<li>micronutrient deficiencies<\/li>\n<li>impaired tissue repair<\/li>\n<\/ul>\n<p>\u201cMy advice is to approach these medications as serious metabolic interventions, to be used after a thoughtful evaluation of risks and benefits,\u201d said Pandya.<\/p>\n<p><a href=\"https:\/\/www.kristinkirkpatrick.com\/meet-kristin\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1c2ok3c\">Kristin Kirkpatrick<\/a>, MS, RDN, the president of KAK Consulting and a dietitian at the Cleveland Clinic Department of Wellness &amp; Preventive Medicine in Ohio, agreed it\u2019s important to plan your weight loss journey carefully.<\/p>\n<p>\u201cYes, side effects of rapid weight loss can and do happen, but working with a healthcare provider and focusing on going above and beyond just taking the shot can help,\u201d she told Healthline.<\/p>\n<p>Experts say you can counter these natural side effects through dedicated practices involving diet and exercise.<\/p>\n<p>\u201cMany of these side effects can be minimized by supporting the body\u2019s physiology and metabolism with targeted lifestyle strategies,\u201d said Pandya.<\/p>\n<p>Among her suggestions are:<\/p>\n<ul>\n<li>consuming at least 1 gram of protein per kilogram of body weight per day<\/li>\n<li>limiting snacks and meal frequency<\/li>\n<li>starting meals with <a href=\"https:\/\/www.healthline.com\/nutrition\/8-fermented-foods\" class=\"content-link css-1c2ok3c\" target=\"_blank\" rel=\"noopener\">fermented foods<\/a> and high fiber vegetables<\/li>\n<li>stress management through techniques such as mindfulness and breath work<\/li>\n<li>structured sleep<\/li>\n<\/ul>\n<p>\u201cWhile [these drugs] are powerful pharmacologic tools, the bedrock of metabolic health remains in intelligent, science-backed lifestyle strategies that support the body\u2019s natural signaling and repair mechanisms,\u201d said Pandya.<\/p>\n<p>\u201cI tell my patients that when you are on these drugs you have to get nutritional bang for every bite,\u201d said Kirkpatrick. \u201cThe mechanism of these drugs leads to a reduced intake of food and, therefore, you can\u2019t really afford to consume foods that provide no nutritional benefit.\u201d<\/p>\n<p>\u201cCardio is great and has many benefits, but resistance training can specifically help with muscle mass,\u201d she said.<\/p>\n<p>Ali noted it\u2019s important to remember the purpose of weight loss programs.<\/p>\n<p>\u201cPeople taking medication for weight loss or even undergoing surgery should realize the goal is to achieve <a href=\"https:\/\/www.healthline.com\/nutrition\/how-much-should-i-weigh\" class=\"content-link css-1c2ok3c\" target=\"_blank\" rel=\"noopener\">a healthy weight<\/a> to minimize obesity-related health conditions and achieve a normal lifespan,\u201d he said.<\/p>\n<p>Losing weight is inherently a difficult task.<\/p>\n<p>First, the body may need to store fat for various physiological reasons, including organ protection, hormone regulation, and nutrient absorption.<\/p>\n<p>Azagury noted that the human body is also programmed to retain some fat in case of food shortages. \u201cYour body is designed to avoid weight loss,\u201d he said. \u201cYou\u2019re fighting tens of thousands of years of evolution when you try to lose weight.\u201d<\/p>\n<p>He added that modern techniques, such as <a href=\"https:\/\/www.healthline.com\/health\/obesity\/bariatric-surgery\" class=\"content-link css-1c2ok3c\" target=\"_blank\" rel=\"noopener\">bariatric surgery<\/a> and new weight loss medications, can make weight reduction a little easier.<\/p>\n<p>\u201cThere is no hierarchy in how we lose weight,\u201d Azagury said. \u201cThere is no better or worse way.\u201d<\/p>\n<p><a href=\"https:\/\/www.healthline.com\/health-news\/whats-the-difference-between-ozempic-wegovy-mounjaro-and-zepbound#insurance\" target=\"_blank\" rel=\"noreferrer noopener\" class=\"content-link css-1c2ok3c\">Ozempic and Wegovy<\/a> are injectable medications containing the active ingredient <a href=\"https:\/\/www.healthline.com\/health\/how-to-get-semaglutide\" class=\"content-link css-1c2ok3c\" target=\"_blank\" rel=\"noopener\">semaglutide<\/a>. Ozempic is approved by the Food and Drug Administration (FDA) for treating <a href=\"https:\/\/www.healthline.com\/health\/type-2-diabetes\" class=\"content-link css-1c2ok3c\" target=\"_blank\" rel=\"noopener\">type 2 diabetes<\/a>, while Wegovy is approved for weight loss and management.<\/p>\n<p><a href=\"https:\/\/www.healthline.com\/health-news\/whats-the-difference-between-ozempic-wegovy-mounjaro-and-zepbound#Mounjaro-and-Zepbound-Tirzepatide-What-to-know\" target=\"_blank\" rel=\"noreferrer noopener\" class=\"content-link css-1c2ok3c\">Mounjaro and Zepbound<\/a> are injectable drugs that contain the active ingredient trizepatide. The FDA approves Mounjaro for type 2 diabetes, while Zepbound is used for weight management.<\/p>\n<p>All these drugs work in the same basic way by suppressing a person\u2019s appetite. They do have some potential side effects. Some of the more common are:<\/p>\n<ul>\n<li>nausea<\/li>\n<li>diarrhea<\/li>\n<li>constipation<\/li>\n<li>abdominal pain<\/li>\n<\/ul>\n<p>These medications have been shown in <a href=\"https:\/\/www.healthline.com\/health-news\/mounjaro-superior-to-ozempic-for-blood-sugar-and-weight-loss-study-finds\" target=\"_blank\" rel=\"noreferrer noopener\" class=\"content-link css-1c2ok3c\">clinical trials<\/a> to help people with obesity and other weight management issues lose weight effectively. People who are prescribed these drugs are advised to <a href=\"https:\/\/www.healthline.com\/health\/how-to-maintain-a-healthy-lifestyle\" class=\"content-link css-1c2ok3c\" target=\"_blank\" rel=\"noopener\">maintain a healthy lifestyle<\/a>.<\/p>\n<ul>\n<li><a href=\"https:\/\/www.healthline.com\/health\/diabetes\/normal-blood-sugar-level\" class=\"content-link css-1c2ok3c\" target=\"_blank\" rel=\"noopener\">blood sugar control<\/a><\/li>\n<li>improving cardiovascular health<\/li>\n<li>lowering kidney disease risk<\/li>\n<li>improving cognitive abilities<\/li>\n<\/ul>\n<p>Experts say lifestyle changes are important. So is developing a weight loss program under the supervision of a medical professional.<\/p>\n<p>Kirkpatrick advised developing a strategy to eventually stop using the weight loss drugs.<\/p>\n<p>\u201cYou should begin thinking about the off ramp when jumping onto the on ramp,\u201d she said. \u201cThis means \u2014 begin planning how you get off the drugs (if this is the plan) once you meet your weight and metabolic goals.\u201d<\/p>\n<p>\u201cOzempic and Zepbound are appropriate for select individuals, but everyone can engage their body\u2019s innate metabolic wisdom by adopting evidence-based lifestyle interventions, resulting in more durable, holistic health,\u201d added Pandya.<\/p>\n<p><script async src=\"\/\/www.instagram.com\/embed.js\"><\/script><\/p>\n","protected":false},"excerpt":{"rendered":"Share on PinterestRecent anecdotal reports have highlighted strange side effects of GLP-1 medications used for weight loss like&hellip;\n","protected":false},"author":2,"featured_media":61629,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4315],"tags":[105,4326,31825,31824,31823,16,15],"class_list":{"0":"post-61628","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-medication","8":"tag-health","9":"tag-medication","10":"tag-ozempic-butt","11":"tag-ozempic-feet","12":"tag-ozempic-mouth","13":"tag-uk","14":"tag-united-kingdom"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@uk\/114424236113947162","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/61628","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/comments?post=61628"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/61628\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media\/61629"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media?parent=61628"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/categories?post=61628"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/tags?post=61628"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}