{"id":620693,"date":"2025-12-08T19:48:38","date_gmt":"2025-12-08T19:48:38","guid":{"rendered":"https:\/\/www.europesays.com\/uk\/620693\/"},"modified":"2025-12-08T19:48:38","modified_gmt":"2025-12-08T19:48:38","slug":"will-it-find-new-treatments","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/uk\/620693\/","title":{"rendered":"will it find new treatments?"},"content":{"rendered":"<p> <img decoding=\"async\" class=\"figure__image\" alt=\"Masked long COVID activists attend a Senate appropriations subcommittee hearing .\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2025\/12\/d41586-025-03904-w_51787690.jpg\"\/><\/p>\n<p class=\"figure__caption u-sans-serif\">Global estimates indicate that 6 in 100 people who get COVID-19 develop post-COVID-19 condition, also known as long COVID.Credit: Tom Williams\/CQ-Roll Call, Inc via Getty<\/p>\n<p>In a major boost to research on long COVID and chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis (ME), the German government has announced that it will provide \u20ac500 million (US$582 million) in research funding to support a National Decade Against Post-Infectious Diseases from <a href=\"https:\/\/www-bmftr-bund-de.translate.goog\/SharedDocs\/Kurzmeldungen\/DE\/2025\/11\/nationale-dekade-postinfekti%C3%B6se-erkrankungen.html?_x_tr_sl=auto&amp;_x_tr_tl=en&amp;_x_tr_hl=en-US&amp;_x_tr_pto=wapp\" data-track=\"click\" data-label=\"https:\/\/www-bmftr-bund-de.translate.goog\/SharedDocs\/Kurzmeldungen\/DE\/2025\/11\/nationale-dekade-postinfekti%C3%B6se-erkrankungen.html?_x_tr_sl=auto&amp;_x_tr_tl=en&amp;_x_tr_hl=en-US&amp;_x_tr_pto=wapp\" data-track-category=\"body text link\" target=\"_blank\" rel=\"noopener\">2026 to 2036<\/a>.<\/p>\n<p>Germany is one of many countries facing an unprecedented health burden owing to long COVID and other post-infection syndromes since the COVID-19 pandemic. Almost one in five people in a German cohort had long COVID in 2022<a href=\"#ref-CR1\" data-track=\"click\" data-action=\"anchor-link\" data-track-label=\"go to reference\" data-track-category=\"references\">1<\/a>, and around one in seven people in the United States were affected by long COVID by late 2023<a href=\"#ref-CR2\" data-track=\"click\" data-action=\"anchor-link\" data-track-label=\"go to reference\" data-track-category=\"references\">2<\/a>. This translates to a significant burden on healthcare and the economy \u2014 the syndrome is estimated to cost the world economy US$1 trillion every year<a href=\"#ref-CR3\" data-track=\"click\" data-action=\"anchor-link\" data-track-label=\"go to reference\" data-track-category=\"references\">3<\/a>.<\/p>\n<p>\u201cFrom many conversations, I know what a great burden these illnesses represent for those affected and their families,\u201d said Dorothee B\u00e4r, the German Federal Research Minister, in a press release announcing the funding. \u201cThere are still no simple solutions or therapies for ME\/CFS and post-viral autoimmune diseases, and previous scientific studies demonstrate the complexity of the disease mechanisms.\u201d<\/p>\n<p>\u201cThis is really major funding,\u201d says Rafael Mikolajczyk, an epidemiologist at Martin Luther University Halle-Wittenberg in Germany. Ziyad Al-Aly, a clinical epidemiologist at Washington University in St. Louis, agrees, saying it\u2019s \u201ca great step in the right direction\u201d. Long COVID has become politicized and \u201cless of a priority for governments around the world,\u201d he adds.<\/p>\n<p>What research is the money expected to support?<\/p>\n<p>The German government aims to fund research into a wide variety of post-infectious diseases, including Long COVID and ME\/CFS. It also aims to cover a range of topics, including the pathophysiology and immunology of the conditions, diagnostics and biomarkers, mental health and neurology, and long-term consequences on health.<\/p>\n<p>The language is deliberately broad, says Al-Aly, who under the Biden administration co-chaired the committee that created the US\u2019s <a href=\"https:\/\/patientresearchcovid19.com\/storage\/2022\/06\/Towards-a-Patient-Driven-National-Research-Action-Plan.pdf\" data-track=\"click\" data-label=\"https:\/\/patientresearchcovid19.com\/storage\/2022\/06\/Towards-a-Patient-Driven-National-Research-Action-Plan.pdf\" data-track-category=\"body text link\" target=\"_blank\" rel=\"noopener\">National Research Action Plan for Long COVID<\/a>. \u201cYou don\u2019t want to shackle your scientists with a very narrow scope,\u201d he says. He applauds the funding for including all post-infectious conditions, which share many commonalities, and for embracing a variety of disciplines.<\/p>\n<p>Because the German funding is not yet allocated, the next step is for scientists and patients to be brought in to shape exactly how the money will be spent, says Ulrike Protzer, a virologist at the Technical University of Munich in Germany.<\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/d41586-025-00995-3\" class=\"u-link-inherit\" data-track=\"click\" data-track-label=\"recommended article\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" class=\"recommended__image\" alt=\"\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2025\/12\/d41586-025-03904-w_50843280.jpg\"\/><\/p>\n<p class=\"recommended__title u-serif\">Long COVID activists fought Trump team\u2019s research cuts and won \u2015 for now<\/p>\n<p><\/a><\/p>\n<p>One fundamental challenge for managing conditions like long COVID is to identify the mechanisms operating in each long COVID patient, says Akiko Iwasaki, an immunologist at Yale School of Medicine, Connecticut. Only then can they be recruited into clinical trials of medications that will treat these root causes. That means link biomarker studies to clinical trials, says Al-Aly \u2013 like giving antivirals primarily to people with persistent viral infections<\/p>\n<p>Nisreen Alwan, a public health specialist at the University of Southampton, UK, also wants to see more research characterising the public health burden of post-infection conditions. \u201cHow do we quantify the burden of acute infections in terms of chronic disease? What are the pathways to prevention? How can we address the risk factors?\u201d She compares viral infections to outdoor air pollution, the impacts of which on cardiovascular health have now been quantified \u2014 spurring efforts to cut pollution levels. \u201cthat&#8217;s where we should be heading for acute viral infections,\u201d she says. <\/p>\n<p><img decoding=\"async\" class=\"figure__image\" alt=\"A woman in a striped knitted sweater looks at the camera from behind a cart loaded with medication bottles in her apartment.\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2025\/12\/d41586-025-03904-w_51787688.jpg\"\/><\/p>\n<p class=\"figure__caption u-sans-serif\">Long-COVID advocates and researchers in the United States managed to revive some of the <a href=\"https:\/\/www.nature.com\/articles\/d41586-025-00703-1\" data-track=\"click\" data-label=\"https:\/\/www.nature.com\/articles\/d41586-025-00703-1\" data-track-category=\"body text link\" target=\"_blank\" rel=\"noopener\">research grants cancelled by the administration of President Donald Trump<\/a>. Credit: Joe Klamar\/AFP via Getty<\/p>\n<p>What happened with previous research drives?<\/p>\n","protected":false},"excerpt":{"rendered":"Global estimates indicate that 6 in 100 people who get COVID-19 develop post-COVID-19 condition, also known as long&hellip;\n","protected":false},"author":2,"featured_media":620694,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[21371,5036,105,3965,3966,1093,70,16,15],"class_list":{"0":"post-620693","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-diseases","9":"tag-funding","10":"tag-health","11":"tag-humanities-and-social-sciences","12":"tag-multidisciplinary","13":"tag-public-health","14":"tag-science","15":"tag-uk","16":"tag-united-kingdom"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@uk\/115685682839690665","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/620693","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/comments?post=620693"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/620693\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media\/620694"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media?parent=620693"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/categories?post=620693"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/tags?post=620693"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}