{"id":801716,"date":"2026-03-03T18:12:20","date_gmt":"2026-03-03T18:12:20","guid":{"rendered":"https:\/\/www.europesays.com\/uk\/801716\/"},"modified":"2026-03-03T18:12:20","modified_gmt":"2026-03-03T18:12:20","slug":"scientists-say-this-cardio-damages-red-blood-cells","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/uk\/801716\/","title":{"rendered":"Scientists Say This Cardio Damages Red Blood Cells"},"content":{"rendered":"<p><img src=\"https:\/\/www.prevention.com\/_assets\/design-tokens\/fre\/static\/icons\/clock-regular.4ddebeb.svg\" alt=\"Estimated read time\" width=\"16\" height=\"16\" decoding=\"async\" loading=\"lazy\"\/>3 min read<img src=\"https:\/\/www.prevention.com\/_assets\/design-tokens\/fre\/static\/icons\/caret-right-regular.a6ec664.svg\" alt=\"Caret Right\" width=\"100%\" height=\"auto\" decoding=\"async\" loading=\"lazy\"\/><\/p>\n<ul>\n<li>Scientists link high-intensity, long-distance cardio (like marathon running) to red blood cell damage in a recent study. <\/li>\n<li>Researchers looked at the state of runners\u2019 red blood cells before and after a trail race and ultramarathon.<\/li>\n<li>The cells showed evidence of oxidative stress and damage. Experts explain the health implications.<\/li>\n<\/ul>\n<p data-journey-content=\"true\" data-node-id=\"0\" class=\"css-6wxqfj emevuu60\">Research shows that anything from walking to <a href=\"https:\/\/www.prevention.com\/fitness\/a70059489\/strength-training-adds-years-to-life-study\/\" target=\"_self\" data-vars-ga-outbound-link=\"https:\/\/www.prevention.com\/fitness\/a70059489\/strength-training-adds-years-to-life-study\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"strength training may add years to your life\" data-node-id=\"0.1\" class=\"body-link css-1xnf0nh emevuu60\" rel=\"noopener\">strength training may add years to your life<\/a>, underlying the importance of exercise. But there are so many different ways to get your blood pumping, and not all of them have the same impact on your body. Now, scientists say that a specific type of intense exercise, long-distance trail running, damages red blood cells. But experts say there\u2019s more to it.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"1\" class=\"body-tip css-txvov emevuu60\">Meet the Experts: <a href=\"https:\/\/go.redirectingat.com?id=74968X1576256&amp;url=https%3A%2F%2Fwww.parsleyhealth.com%2Fteam%2Fdayna-mccarthy\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.parsleyhealth.com\/team\/dayna-mccarthy\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"Dayna McCarthy, D.O.\" data-vars-ga-product-id=\"69af5220-cec1-45b7-a1ed-7ecc01d4ec8a\" rel=\"nofollow noopener\" data-node-id=\"1.1\" data-href=\"https:\/\/www.parsleyhealth.com\/team\/dayna-mccarthy\" data-product-url=\"https:\/\/www.parsleyhealth.com\/team\/dayna-mccarthy\" data-affiliate=\"true\" data-affiliate-url=\"https:\/\/go.redirectingat.com?id=74968X1576256&amp;url=https%3A%2F%2Fwww.parsleyhealth.com%2Fteam%2Fdayna-mccarthy\" data-affiliate-network=\"{&quot;afflink_redirect&quot;:&quot;\/_p\/afflink\/12LJE\/parsleyhealth-dayna-mccarthy-do&quot;,&quot;site_id&quot;:&quot;d55f98dc-cbd6-4679-ae11-243969f8c772&quot;,&quot;network&quot;:{&quot;name&quot;:&quot;Skimlinks&quot;}}\" data-vars-ga-product-price=\"$0.00\" data-vars-ga-product-retailer-id=\"32956bf8-688f-48a7-afe0-d66dd76c25cd\" data-vars-ga-link-treatment=\"(not set) | (not set)\" class=\"body-link product-links css-1xnf0nh e1aq0z090\">Dayna McCarthy, D.O.<\/a>, a double board-certified obesity medicine and sports and interventional spine medicine specialist at Parsley Health; and <a href=\"https:\/\/www.sentara.com\/find-a-doctor-or-provider\/Talreja-Deepak-8038\" data-vars-ga-outbound-link=\"https:\/\/www.sentara.com\/find-a-doctor-or-provider\/Talreja-Deepak-8038\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"Deepak Talreja, M.D., \" data-node-id=\"1.3\" class=\"body-link css-1xnf0nh emevuu60\" target=\"_blank\" rel=\"noopener\">Deepak Talreja, M.D., <\/a>clinical chief of cardiology at Sentara Health.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"2\" class=\"css-6wxqfj emevuu60\">Researchers looked at the red blood cell counts of a small number of ultra-marathon runners post-race and found that the bouts of extreme exercise caused damage that accelerated aging of the cells. Red blood cells work to deliver oxygen to the lungs and carry nutrients throughout the body, so you could say they\u2019re pretty important to health. Which is why they\u2019re examined as markers for conditions like anemia, malnutrition, and leukemia, per the <a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/red-blood-cell\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/red-blood-cell\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"National Cancer Institute\" data-node-id=\"2.1\" class=\"body-link css-1xnf0nh emevuu60\" rel=\"noopener\">National Cancer Institute<\/a>.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"4\" class=\"css-6wxqfj emevuu60\">So, does this mean completing a marathon (or ultra-marathon) does more harm than good? Not quite. The study, published in <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S3050598426000107?ref=pdf_download&amp;fr=RR-2&amp;rr=9d30fa3628fbcc3a\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S3050598426000107?ref=pdf_download&amp;fr=RR-2&amp;rr=9d30fa3628fbcc3a\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"Blood Red Cells and Iron\" data-node-id=\"4.1\" class=\"body-link css-1xnf0nh emevuu60\" rel=\"noopener\">Blood Red Cells and Iron<\/a>, consisted of 23 runners who completed a 40-kilometer trail race and a 171-kilometer ultramarathon, blood tests (compared to pre-race tests) showed clear signs of oxidative and inflammatory damage to red blood cells, explains <a href=\"https:\/\/go.redirectingat.com?id=74968X1576256&amp;url=https%3A%2F%2Fwww.parsleyhealth.com%2Fteam%2Fdayna-mccarthy\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.parsleyhealth.com\/team\/dayna-mccarthy\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"Dayna McCarthy, D.O.\" data-vars-ga-product-id=\"69af5220-cec1-45b7-a1ed-7ecc01d4ec8a\" rel=\"nofollow noopener\" data-node-id=\"4.4\" data-href=\"https:\/\/www.parsleyhealth.com\/team\/dayna-mccarthy\" data-product-url=\"https:\/\/www.parsleyhealth.com\/team\/dayna-mccarthy\" data-affiliate=\"true\" data-affiliate-url=\"https:\/\/go.redirectingat.com?id=74968X1576256&amp;url=https%3A%2F%2Fwww.parsleyhealth.com%2Fteam%2Fdayna-mccarthy\" data-affiliate-network=\"{&quot;afflink_redirect&quot;:&quot;\/_p\/afflink\/12LJE\/parsleyhealth-dayna-mccarthy-do&quot;,&quot;site_id&quot;:&quot;d55f98dc-cbd6-4679-ae11-243969f8c772&quot;,&quot;network&quot;:{&quot;name&quot;:&quot;Skimlinks&quot;}}\" data-vars-ga-product-price=\"$0.00\" data-vars-ga-product-retailer-id=\"32956bf8-688f-48a7-afe0-d66dd76c25cd\" data-vars-ga-link-treatment=\"(not set) | (not set)\" class=\"body-link product-links css-1xnf0nh e1aq0z090\">Dayna McCarthy, D.O.<\/a>, a double board-certified obesity medicine and sports and interventional spine medicine specialist at Parsley Health. After the ultramarathon, especially, the body showed strong inflammation, red blood cells showed signs of oxidative stress (a.k.a. chemical wear and tear), and the cells became slightly less flexible, adds <a href=\"https:\/\/www.sentara.com\/find-a-doctor-or-provider\/Talreja-Deepak-8038\" data-vars-ga-outbound-link=\"https:\/\/www.sentara.com\/find-a-doctor-or-provider\/Talreja-Deepak-8038\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"Deepak Talreja, M.D., \" data-node-id=\"4.6\" class=\"body-link css-1xnf0nh emevuu60\" target=\"_blank\" rel=\"noopener\">Deepak Talreja, M.D., <\/a>clinical chief of cardiology at Sentara Health.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"5\" class=\"css-6wxqfj emevuu60\">Red blood cells work to deliver oxygen to the lungs and carry nutrients throughout the body, so you could say they\u2019re pretty important to health. Which is why they\u2019re examined as markers for conditions like anemia, malnutrition, and leukemia, per the <a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/red-blood-cell\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/red-blood-cell\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"National Cancer Institute\" data-node-id=\"5.1\" class=\"body-link css-1xnf0nh emevuu60\" rel=\"noopener\">National Cancer Institute<\/a>.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"6\" class=\"css-6wxqfj emevuu60\">The study results may sound jarring at first, but it\u2019s important to note that <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK539702\/\" target=\"_blank\" data-vars-ga-outbound-link=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK539702\/\" data-vars-ga-ux-element=\"Hyperlink\" data-vars-ga-call-to-action=\"red blood cells only live about 120 days\" data-node-id=\"6.1\" class=\"body-link css-1xnf0nh emevuu60\" rel=\"noopener\">red blood cells only live about 120 days<\/a>. Daily life damages them over time, and they are then removed by the spleen and liver. \u201cThat is normal aging at the cellular level,\u201d says Dr. Talreja.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"7\" class=\"css-6wxqfj emevuu60\">In the runners\u2019 cases, racing accelerated that life cycle, only temporarily. And researchers didn\u2019t follow up to examine whether or not the isolated events caused long-term damage. Plus: \u201cBone marrow constantly produces new red blood cells,\u201d explains Dr. Talreja. \u201cHealthy athletes typically replace these cells quickly, and there is no evidence that this process causes systemic aging of the person.\u201d<\/p>\n<p data-journey-content=\"true\" data-node-id=\"8\" class=\"css-6wxqfj emevuu60\">Theoretically, if the runners engaged in intense marathons too often, there may be more risk of long-term damage because the blood markers were similar to those seen in severe infections and systemic inflammatory states, says Dr. McCarthy. But more research is needed, and scientists have yet to prove this. Red blood cells that don\u2019t work well over time may lead to stress on the vascular system, negatively impact blood flow, and lead to to low-grade inflammation, which impact aging and cardiovascular disease.<\/p>\n<p>Why cardio remains good for health and longevity<\/p>\n<p data-journey-content=\"true\" data-node-id=\"10\" class=\"css-6wxqfj emevuu60\">\u201cRegular running and higher cardiorespiratory fitness are associated with lower all\u2011cause and cardiovascular mortality,\u201d explains Dr. McCarthy. Moderate to moderately high volumes lead to the most benefits, and the risk from very extreme amounts, if present at all, is small, she says.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"11\" class=\"css-6wxqfj emevuu60\">\u201cCardiorespiratory fitness is one of the strongest predictors of survival we have. Modest, consistent cardio\u2014such as brisk walking, moderate intensity running, or cycling\u2014delivers most of the longevity benefit,\u201d she says.<\/p>\n<p>The bottom line<\/p>\n<p data-journey-content=\"true\" data-node-id=\"13\" class=\"css-6wxqfj emevuu60\">\u201cExtreme, single bout, ultra-endurance running acutely pushes red blood cells and the immune and metabolic systems into a state that looks like accelerated red blood cell aging with significant oxidative and inflammatory stress,\u201d says Dr. McCarthy. For most healthy, well-prepared athletes, this likely shows a short-term stress, followed by making it up (with nourishment and hydration).<\/p>\n<p data-journey-content=\"true\" data-node-id=\"14\" class=\"css-6wxqfj emevuu60\">Hefty data shows that moderate-to-high levels of aerobic fitness have a strong association with longer life expectancy, adds Dr. Talreja. Even endurance athletes who race often generally show positive cardiovascular patterns compared with people who lead more sedentary lifestyles.<\/p>\n<p data-journey-content=\"true\" data-node-id=\"15\" class=\"css-6wxqfj emevuu60\">Experts advise exercising caution in high-stress and high-impact physical activity. But more research is needed before making any definitive decisions. As always, consult your physician before changing up your routine. <strong data-node-id=\"15.1\"><br data-node-id=\"15.1.0\"\/><\/strong><\/p>\n<p>Related Stories<\/p>\n","protected":false},"excerpt":{"rendered":"3 min read Scientists link high-intensity, long-distance cardio (like marathon running) to red blood cell damage in a&hellip;\n","protected":false},"author":2,"featured_media":801717,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4322],"tags":[218314,218315,14774,232363,1331,1630,3989,105,1381,232364,232362,16,15],"class_list":{"0":"post-801716","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-fitness","8":"tag-collection-health-news","9":"tag-collection-health-studies","10":"tag-content-type-news-explainer","11":"tag-contentid-314bf4a8-16a0-4790-9673-07f336dbf3b7","12":"tag-displaytype-standard-article","13":"tag-fitness","14":"tag-hasproduct-true","15":"tag-health","16":"tag-locale-us","17":"tag-read_time-4","18":"tag-shorttitle-scientists-say-this-cardio-damages-red-blood-cells","19":"tag-uk","20":"tag-united-kingdom"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@uk\/116166600379124204","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/801716","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/comments?post=801716"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/801716\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media\/801717"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media?parent=801716"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/categories?post=801716"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/tags?post=801716"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}