{"id":942601,"date":"2026-05-06T23:46:53","date_gmt":"2026-05-06T23:46:53","guid":{"rendered":"https:\/\/www.europesays.com\/uk\/942601\/"},"modified":"2026-05-06T23:46:53","modified_gmt":"2026-05-06T23:46:53","slug":"the-ideal-tretinoin-skin-care-routine-approved-by-dermatologists","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/uk\/942601\/","title":{"rendered":"The Ideal Tretinoin Skin Care Routine, Approved by Dermatologists"},"content":{"rendered":"<p id=\"anchor-e6a881\" class=\"body-graf\">When my dermatologist prescribed me Tretinoin for <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-cystic-acne-treatments-ncna1303082\" target=\"_blank\" rel=\"noopener\">cystic acne<\/a> six years ago, I only had one question: How do I incorporate it into my <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-skin-care-routine-rcna105133\" target=\"_blank\" rel=\"noopener\">skin care routine<\/a>? I was brand new to the world of <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-retinol-creams-serums-acne-wrinkles-ncna1244298\" target=\"_blank\" rel=\"noopener\">retinoids<\/a> and honestly put off by them due to side effects I\u2019d heard people talk about on social media. But with some coaching from my doctor and a little trial and error, I figured out how to build a Tretinoin skin care routine. It\u2019s simple and revolves around gentle, hydrating, noncomedogenic products that support my skin while letting the medication do its thing.<\/p>\n<p id=\"anchor-0b18b9\" class=\"body-graf\">Below is the Tretinoin skin care guide I wish I had when I started using the medication. I\u2019m walking you through the best products to pair with Tretinoin, what order to use them in and how to get through the dreaded retinoid uglies. I also spoke to four dermatologists about literally everything you\u2019d want to know about Tretinoin so you can find all the answers in one place.<\/p>\n<p id=\"anchor-1320a0\" class=\"body-graf\"><strong>Want more from NBC Select? <\/strong><a href=\"https:\/\/link.nbcnews.com\/join\/5cj\/nbc-news-select-signup-pd\" target=\"_blank\" rel=\"noopener\"><strong>Sign up<\/strong><\/a><strong> for our newsletter, The Selection, and shop smarter.<\/strong><\/p>\n<p><a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-28284c\" id=\"anchor-28284c\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">What\u2019s the ideal Tretinoin skin care routine?<\/a><\/p>\n<p id=\"anchor-29aa0c\" class=\"body-graf\">To give you an idea of what a basic skin care routine looks like while on Tretinoin, I\u2019m breaking down the one I follow every morning and evening below. I talked to dermatologists to make sure it aligns with their recommendations, and I included their advice for each step (learn more about how to build a Tretinoin skin care routine below).<\/p>\n<p id=\"anchor-a880e3\" class=\"body-graf\">For context, I\u2019ve been using Tretinoin cream at a 0.025% concentration since 2020, and I\u2019m also on Sprinolactone. Prior to starting Tretinoin, I had severe cystic acne and <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-acne-scar-treatments-ncna1273575\" target=\"_blank\" rel=\"noopener\">acne scars<\/a>, and I\u2019d tried every over-the-counter product you can think of, including <a href=\"https:\/\/www.amazon.com\/Differin-Adapalene-prescription-strength-treatment\/dp\/B07ZTN5N1V\" target=\"_blank\" rel=\"noopener\">Differin<\/a>. I have <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/100-best-sensitive-skin-care-products-rcna254025\" target=\"_blank\" rel=\"noopener\">sensitive<\/a>, acne-prone, combination skin that leans dry, and I apply Tretinoin every other night. I\u2019ve done most of this skin care routine since I started the medication, and I\u2019ve added to it over the years as my skin adjusted to being on Tret. It\u2019s important to note that while this routine and these products work for me, everyone\u2019s skin is different, so consult your dermatologist for personalized recommendations.<\/p>\n<p><a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-6391b2\" id=\"anchor-6391b2\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">A.M. Tretinoin skin care routine<\/a><a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-5a4607\" id=\"anchor-5a4607\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">Step 1: cleanser<\/a><\/p>\n<p id=\"anchor-bc7bb9\" class=\"body-graf\">Washing your face in the morning gets rid of dirt, oil and debris that accumulated overnight, experts told me. It essentially wipes the slate clean, giving products the best shot at absorbing into your skin and working as effectively as possible.  Pick a <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-cleansers-dry-skin-rcna135139\" target=\"_blank\" rel=\"noopener\">cleanser<\/a> that just cleans and, if possible, hydrates skin \u2014 it shouldn\u2019t have additional <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-exfoliating-products-rcna104357\" target=\"_blank\" rel=\"noopener\">exfoliating<\/a> ingredients in it, like alpha hydroxy acids (<a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-alpha-hydroxy-acid-products-rcna248479\" target=\"_blank\" rel=\"noopener\">AHAs<\/a>) or beta hydroxy acids (<a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/bha-products-skincare-routine-ncna1281226\" target=\"_blank\" rel=\"noopener\">BHAs<\/a>).<\/p>\n<p><a href=\"https:\/\/www.amazon.com\/Bioderma-Fragrance-Free-Alcohol-Free-Technology-Sensitive\/dp\/B00AVE22XS?tag=tretinoinskincareroutinercna343135-20\" data-product-id=\"rcpd55857\" data-aps-asc-tag=\"tretinoinskincareroutinercna343135-20\" data-aps-asin=\"B00AVE22XS\" rel=\"sponsored noopener noreferrer\" target=\"_blank\" data-testid=\"product-picture-link\" class=\"w-100\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/AMAZON-Bioderma-Sensibio-H2O-Micellar-Water-Pump-Makeup-Remover-Cleanser-Gentle-for-Skin-Fragrance-F.jpeg\" alt=\"Bioderma Sensibio H2O Micellar Water\" height=\"500\" width=\"500\"\/><\/a><\/p>\n<p>What we like<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Non-drying<\/li>\n<li>No-rinse<\/li>\n<li>Convenient pump cap<\/li>\n<\/ul>\n<p>Something to note<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Not ideal w\/ waterproof makeup<\/li>\n<\/ul>\n<p id=\"anchor-2d9846\" class=\"body-graf\">I use <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-micellar-water-rcna232435\" target=\"_blank\" rel=\"noopener\">micellar water<\/a> as my morning cleanser \u2014 I\u2019d rather soak a cotton pad and wipe it across my face than lather a cleanser and rinse it off when I\u2019m still half asleep. I also find micellar water to be refreshing, hydrating and soothing. I religiously buy Bioderma\u2019s Sensibio Micellar Water because it\u2019s fragrance- and alcohol-free, and I swear I feel it lifting grime off my skin as I use it. I get the bottle with the pump cap (a jumbo size of which I add to my cart at <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/costco-membership-guide-perks-fees-rcna244782\" target=\"_blank\" rel=\"noopener\">Costco<\/a>), which helps me control how much micellar water I dispense at a time.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/bioderma-sensibio-micellar-water-8d8f0f.jpg\" alt=\"A woman applying Bioderma\u2019s Sensibio Micellar Water to her skin.\" height=\"1200\" width=\"1200\"\/>The micellar water removes grime that built-up on my skin overnight and wakes it up first thing in the morning since it\u2019s so refreshing.Courtesy Zoe Malin<a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-add398\" id=\"anchor-add398\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">Step 2: vitamin C serum<\/a><\/p>\n<p id=\"anchor-78611c\" class=\"body-graf\">\u201cVitamin C helps counteract what we call reactive oxygen species, which are unstable free radicals found in pollution and other exposures like UV light,\u201d says Dr. <a href=\"https:\/\/nyulangone.org\/doctors\/1316300296\/emily-c-milam\" target=\"_blank\" rel=\"noopener\">Emily Milam<\/a>, a board-certified dermatologist at NYU Langone Health. Exposure to reactive oxygen species can damage skin and speed up aging by breaking down collagen and elastin, but vitamin C serums help protect skin to prevent these issues.<\/p>\n<p id=\"anchor-1d5d88\" class=\"body-graf\">Since I live in New York City, which is highly polluted (no shade \u2014 it\u2019s just the truth), and I <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-womens-running-shoes-tested-rcna255629\" target=\"_blank\" rel=\"noopener\">run<\/a> over 30 miles a week, mostly outdoors, I figured using a <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-vitamin-c-serums-rcna240620\" target=\"_blank\" rel=\"noopener\">vitamin C serum<\/a> could only benefit me. I added one to my routine about a year into my Tretinoin treatment when my skin was used to the medication. \u201cVitamin C serum can certainly be used with retinoids like Tretinoin, but some acne-prone people don\u2019t tolerate them,\u201d says Milam. Finding the right one for you might take some time \u2014 I went through a handful before finding one that I liked. Milam also recommends only applying vitamin C serum in the morning, separating it from Tretinoin application at night.<\/p>\n<p><a href=\"https:\/\/www.amazon.com\/Summer-Fridays-CC-Me-Serum\/dp\/B08ZH82P7P?tag=tretinoinskincareroutinercna343135-20\" data-product-id=\"rcpd73055\" data-aps-asc-tag=\"tretinoinskincareroutinercna343135-20\" data-aps-asin=\"B08ZH82P7P\" rel=\"sponsored noopener noreferrer\" target=\"_blank\" data-testid=\"product-picture-link\" class=\"w-100\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/AMAZON-Summer-Fridays-CC-Me-Serum-with-Vitamin-C--Niacinamide---Brightening--Hydrating-Face-Serum-to.jpeg\" alt=\"Summer Fridays CC Me Serum\" height=\"500\" width=\"500\"\/><\/a><\/p>\n<p>What we like<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Gentle on sensitive skin<\/li>\n<li>Brightens &amp; evens out tone<\/li>\n<li>Non-greasy, non-sticky feel<\/li>\n<\/ul>\n<p id=\"anchor-148cde\" class=\"body-graf\">I tried a few vitamin C serums made with L-ascorbic acid, the most effective and active type of vitamin C, but I found every single one irritating. My already sensitive skin is even more sensitive on Tret, so it just couldn\u2019t handle the strong ingredient. I eventually moved to products made with more gentle, inactive forms of vitamin C and had the most luck with Summer Fridays\u2019 vitamin C serum, so I\u2019ve stuck with it ever since. It\u2019s formulated with two types of vitamin C (3-O-ethyl ascorbic acid and ascorbyl glucoside), as well as <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-niacinamide-products-ncna1303572\" target=\"_blank\" rel=\"noopener\">niacinamide<\/a>, and I\u2019ve noticed that my skin looks brighter and has a more even tone with consistent use. The serum comes in a pump bottle, which helps me dispense a pea-sized drop every time, and it has a super smooth, non-greasy and non-sticky feel. It absorbs into my skin quickly so I can quickly layer other products on top.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/Summer-Fridays-CC-Me-serum-1b2e0e.jpg\" alt=\"A woman applying Summer Fridays\u2019 CC Me Serum.\" height=\"1200\" width=\"1200\"\/>Summer Fridays\u2019 vitamin C serum is one of the only options I\u2019ve tested that hasn\u2019t irritated my sensitive, acne-prone skin when I apply it daily in the morning.Courtesy Zoe Malin<a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-b31900\" id=\"anchor-b31900\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">Step 3: hyaluronic acid serum<\/a><\/p>\n<p id=\"anchor-f0b0e9\" class=\"body-graf\">My skin typically needs a thick, rich <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/100-best-face-moisturizers-rcna151958\" target=\"_blank\" rel=\"noopener\">moisturizer<\/a> to really prevent dryness, but lightweight options layer better under makeup, in my experience. For an extra boost of hydration, I use a <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-hyaluronic-acid-serums-creams-ncna1290282\" target=\"_blank\" rel=\"noopener\">hyaluronic acid serum<\/a> every morning and pair it with a lightweight moisturizer, which essentially gives me the benefits of a thick, rich moisturizer without actually applying one. It\u2019s a trick my dermatologist taught me, and one that comes recommended by Dr. <a href=\"https:\/\/www.monadermatology.com\/team-member\/about-mona\/\" target=\"_blank\" rel=\"noopener\">Mona Foad<\/a>, a board-certified dermatologist and founder of <a href=\"https:\/\/www.monadermatology.com\" target=\"_blank\" rel=\"noopener\">MONA Dermatology<\/a>.<\/p>\n<p><a href=\"https:\/\/www.amazon.com\/Ordinary-Hyaluronic-Acid-2-30ml\/dp\/B01MYEZPC8?tag=tretinoinskincareroutinercna343135-20\" data-product-id=\"rcpd51801\" data-aps-asc-tag=\"tretinoinskincareroutinercna343135-20\" data-aps-asin=\"B01MYEZPC8\" rel=\"sponsored noopener noreferrer\" target=\"_blank\" data-testid=\"product-picture-link\" class=\"w-100\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/AMAZON-The-Ordinary-Hyaluronic-Acid-2--B5-with-Ceramides-Multi-Depth-Hydration-Serum-for-Plumper-Smo.jpeg\" alt=\"The Ordinary Hyaluronic Acid 2% + B5 Serum\" height=\"500\" width=\"500\"\/><\/a><\/p>\n<p>What we like<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Good for sensitive skin<\/li>\n<li>Hydrating<\/li>\n<li>Very lightweight feel<\/li>\n<\/ul>\n<p id=\"anchor-cc09c3\" class=\"body-graf\">Because I constantly slather hyaluronic acid serum on my face (sometimes I\u2019ll reapply during the day or use it at night if my skin feels extra dry), I wanted a relatively affordable, yet still effective, option I wouldn\u2019t mind rebuying all the time. The Ordinary\u2019s is exactly that. It\u2019s under $10, so I toss it in my cart without hesitation \u2014 I couldn\u2019t even tell you how many bottles I\u2019ve bought at this point. When I apply the serum, which is made with five types of hyaluronic acid as well as <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/ceramides-skin-care-rcna135328\" target=\"_blank\" rel=\"noopener\">ceramides<\/a> and B5, I feel my skin drinking it up immediately. It really does feel plumper, smoother and tighter in seconds like the brand says. The serum comes in a dropper bottle, is very lightweight and it dries in less than a minute.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/The-Ordinary-Hyaluronic-Acid-Serum-85bd5a.jpg\" alt=\"A woman applying The Ordinary\u2019s Hyaluronic Acid 2% + B5.\" height=\"1200\" width=\"1200\"\/>My skin starts drinking up The Ordinary\u2019s hyaluronic acid serum as soon as I apply it, and sometimes I use it multiple times a day if I\u2019m extra dry, flaky or irritated. Courtesy Zoe Malin<a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-956e06\" id=\"anchor-956e06\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">Step 4: moisturizer<\/a><\/p>\n<p id=\"anchor-bbf7ee\" class=\"body-graf\">Keeping your skin hydrated while using Tretinoin is extremely important \u2014 if it dries out too much, you can start breaking out, says Foad. In addition to using a noncomedogenic moisturizer, also make sure it\u2019s fragrance-free \u2014 fragrances can irritate the skin, especially when it\u2019s vulnerable like it is when you\u2019re on a retinoid, says Dr. <a href=\"https:\/\/dramywechsler.com\" target=\"_blank\" rel=\"noopener\">Amy Wechsler<\/a>, a board-certified dermatologist and psychiatrist who\u2019s also the co-founder and CEO of <a href=\"https:\/\/spotlessclinics.com\" target=\"_blank\" rel=\"noopener\">Spotless Clinics<\/a>. Additionally, try to buy a ceramide-based moisturizer that\u2019s sold in a tub, which tends to be more hydrating than ones sold in a pump or tube, says Milam.<\/p>\n<p><a href=\"https:\/\/www.amazon.com\/dp\/B004JVSGWU?tag=tretinoinskincareroutinercna343135-20\" data-product-id=\"rcpd61939\" data-aps-asc-tag=\"tretinoinskincareroutinercna343135-20\" data-aps-asin=\"B004JVSGWU\" rel=\"sponsored noopener noreferrer\" target=\"_blank\" data-testid=\"product-picture-link\" class=\"w-100\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/AMAZON-Kiehls-Ultra-Facial-Cream-with-45-Squalane-to-Strengthen-Skins-Moisture-Barrier-Skin-Feels-So.jpeg\" alt=\"Kiehl's Ultra Facial Cream\" height=\"500\" width=\"500\"\/><\/a><\/p>\n<p>What we like<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Lightweight<\/li>\n<li>Rich &amp; creamy, yet non-greasy<\/li>\n<li>Sits well under makeup<\/li>\n<\/ul>\n<p>Something to note<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Nothing to note at this time<\/li>\n<\/ul>\n<p id=\"anchor-6aba3b\" class=\"body-graf\">My skin was so sensitive, flaky and irritated for the first few weeks after I started Tretinoin that most moisturisers stung when I applied them. Kiehl\u2019s fragrance-free Ultra Facial Cream is one of the only ones that didn\u2019t, so I became a repeat buyer and still am today. It\u2019s made with <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-squalene-products-rcna101821\" target=\"_blank\" rel=\"noopener\">squalane<\/a>, ceramides and glacial glycoproteins, all ingredients that hydrate skin, repair the barrier and prevent water loss, according to the brand. The moisturizer is very rich and creamy, but it isn\u2019t thick or greasy, and it feels lightweight on my skin, which soaks it up in seconds. I apply makeup directly over it without issues. The cream has a slight cooling effect, too, and it soothes and softens my skin no matter what condition it\u2019s in. Once you finish a jar, you can <a href=\"https:\/\/www.amazon.com\/Kiehls-Strengthen-Long-Lasting-Hydration-Fast-Absorbing\/dp\/B0BJCVRT8K?tag=tretinoinskincareroutinercna343135-20\" rel=\"sponsored noopener\" target=\"_blank\" data-commerce-encoding=\"true\" data-seller-id=\"ncrg916911\">refill it.<\/a><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/Kiehls-Ultra-Facial-Cream-78d039.jpg\" alt=\"A woman applying Kiehl\u2019s Ultra Facial Cream.\" height=\"1200\" width=\"1200\"\/>I wear this moisturizer under makeup and it never pills or looks cakey \u2014 it\u2019s actually a great primer.Courtesy Zoe Malin<a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-bc88ad\" id=\"anchor-bc88ad\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">Step 5: sunscreen<\/a><\/p>\n<p id=\"anchor-44bf63\" class=\"body-graf\"><a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/100-best-face-sunscreens-rcna211891\" target=\"_blank\" rel=\"noopener\">Sunscreen<\/a> is a nonnegotiable part of everyone\u2019s skin care routine, but it\u2019s even more crucial to wear daily if you\u2019re on Tretinoin. The medication makes your skin extra sensitive to the sun, so your threshold to get a <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-products-treat-sunburn-ncna1272746\" target=\"_blank\" rel=\"noopener\">sunburn<\/a> is much lower, says Milam. Per the <a href=\"https:\/\/www.aad.org\/public\/everyday-care\/sun-protection\/shade-clothing-sunscreen\/practice-safe-sun\" target=\"_blank\" rel=\"noopener\">American Academy of Dermatology<\/a>, use a face sunscreen that has an SPF of at least 30 and offers broad-spectrum protection, which means it shields you from UVA and UVB rays. Also pick a formula that aligns with your skin type, be it <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-sunscreen-acne-rcna203278\" target=\"_blank\" rel=\"noopener\">acne-prone<\/a> and <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-sunscreens-for-sensitive-skin-rcna342357\" target=\"_blank\" rel=\"noopener\">sensitive<\/a> or <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-sunscreens-oily-skin-ncna1305286\" target=\"_blank\" rel=\"noopener\">oily<\/a>, for example.<\/p>\n<p><a href=\"https:\/\/www.amazon.com\/Tower-28-SunnyDays-Sunscreen-Foundation\/dp\/B0BBFWFN42?tag=tretinoinskincareroutinercna343135-20\" data-product-id=\"rcpd45501\" data-aps-asc-tag=\"tretinoinskincareroutinercna343135-20\" data-aps-asin=\"B0BBFWFN42\" rel=\"sponsored noopener noreferrer\" target=\"_blank\" data-testid=\"product-picture-link\" class=\"w-100\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/Screenshot-2025-02-28-at-10-13f76f.png\" alt=\"Tower 28 SunnyDays SPF 30 Tinted Mineral Sunscreen\" height=\"691\" width=\"688\"\/><\/a><\/p>\n<p><strong>Coverage:<\/strong> light\u00a0| <strong>Consistency:<\/strong> liquid\u00a0| <strong>Finish:<\/strong> natural\u00a0| <strong>Noncomedogenic:<\/strong> yes\u00a0| <strong>Fragrance-free:<\/strong> yes\u00a0| <strong>Shades:<\/strong> 17<\/p>\n<p>What we like<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Buildable coverage<\/li>\n<li>Gentle formula<\/li>\n<li>SPF protection, matte finish<\/li>\n<\/ul>\n<p>Something to note<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Not many shades (17 available)<\/li>\n<li>Very light coverage<\/li>\n<\/ul>\n<p id=\"anchor-3eafe3\" class=\"body-graf\">I wear <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-tinted-sunscreens-tested-rcna342301\" target=\"_blank\" rel=\"noopener\">tinted sunscreen<\/a> as a base for my makeup every day \u2014 using <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-foundations-acne-prone-skin-rcna213585#:~:text=Glossier%20Stretch%20Fluid%20Foundation,-$34.00&amp;text=Glossier%20is%20an%20NBC%20Select,husband&#039;s%20clothes%20throughout%20the%20day.&amp;text=The%20finish%20is%20very%20natural,orange%E2%80%A6%20a%20perfect%20blend.%E2%80%9D\" target=\"_blank\" rel=\"noopener\">foundation<\/a> daily is way too much makeup for my acne-prone skin, and having SPF built into the product I use to reduce redness and blur imperfections cuts out an additional step in my routine. <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/tower-28-amy-liu-favorite-products-rcna225638\" target=\"_blank\" rel=\"noopener\">Tower 28<\/a>\u2019s tinted sunscreen is one of my top picks (as is the brand\u2019s <a href=\"https:\/\/www.amazon.com\/Tower-28-All-Over-Hydrating-Concealer\/dp\/B0CFWMNJX2?tag=tretinoinskincareroutinercna343135-20\" rel=\"sponsored noopener\" target=\"_blank\" data-commerce-encoding=\"true\" data-seller-id=\"ncrg916911\">Swipe Serum Concealer<\/a>). The fragrance-free, lightweight, broad-spectrum, <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-mineral-sunscreens-rcna208347\" target=\"_blank\" rel=\"noopener\">mineral formula<\/a> has buildable coverage and a natural matte finish \u2014 one layer is usually plenty to correct my skin tone, calm down redness and cover up scarring and acne. The SPF is also specifically designed for acne-prone and sensitive skin like mine, which makes me feel extra confident that it won\u2019t irritate when I use it.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/240617-tinted-spf-oo-inline-tower28-a912f2.jpg\" alt=\"A woman before (left) and after (right) applying the Tower 28 SunnyDays SPF 30 Tinted Sunscreen in shade 13, La Cienega.\" height=\"1200\" width=\"1200\"\/>I only need about one layer of Tower 28\u2019s tinted SPF to correct my skin tone and hide the majority of my acne scars, plus I add the brand\u2019s concealer where needed.Courtesy Zoe Malin<a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-d825f6\" id=\"anchor-d825f6\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">P.M. Tretinoin skin care routine<\/a><a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-92768e\" id=\"anchor-92768e\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">Step 1: double cleanse<\/a><\/p>\n<p id=\"anchor-cb4c8b\" class=\"body-graf\">Always apply Tretinoin to clean, dry skin, which ensures that the medication maintains its potency and will be the most effective, says Milam. I find <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/what-is-double-cleansing-rcna248008\" target=\"_blank\" rel=\"noopener\">double cleansing<\/a> to be the best way to get rid of dirt, oils, skin care products and makeup at the end of the day. It involves two steps: washing your face with an oil-based cleanser to remove surface-level products like makeup and sunscreen, and then washing your face again with a water-based cleanser that removes everything else.<\/p>\n<p><a href=\"https:\/\/www.amazon.com\/Farmacy-Natural-Makeup-Remover-Cleansing\/dp\/B0F45BYH43?tag=tretinoinskincareroutinercna343135-20\" data-product-id=\"rcpd70445\" data-aps-asc-tag=\"tretinoinskincareroutinercna343135-20\" data-aps-asin=\"B0F45BYH43\" rel=\"sponsored noopener noreferrer\" target=\"_blank\" data-testid=\"product-picture-link\" class=\"w-100\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/s2860302-main-zoom-bb0378.webp\" alt=\"Farmacy Green Clean Cleansing Balm\" height=\"700\" width=\"700\"\/><\/a><\/p>\n<p>What we like<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Removes all makeup &amp; skin care<\/li>\n<li>Soft &amp; hydrated skin post-use<\/li>\n<li>No rubbing\/scrubbing required<\/li>\n<\/ul>\n<p>Something to note<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Nothing to note at this time<\/li>\n<\/ul>\n<p id=\"anchor-2b1689\" class=\"body-graf\">Farmacy\u2019s <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-cleansing-balms-rcna123825\" target=\"_blank\" rel=\"noopener\">cleansing balm<\/a> melts even the heaviest, most caked-on makeup and skin care products off my face. I gently massage it into my skin and watch everything lift off the surface as the balm becomes milky, and then I soak a <a href=\"https:\/\/www.amazon.com\/dp\/B07PBXXNCY?tag=tretinoinskincareroutinercna343135-20\" rel=\"sponsored noopener\" target=\"_blank\" data-commerce-encoding=\"true\" data-seller-id=\"ncrg916911\">Clean Skin Club cloth<\/a> in warm water and wipe it all off. I don\u2019t need to rub or scrub \u2014 the cleansing balm does all the work and leaves my skin soft and hydrated. It has a buttery feel, but it\u2019s not greasy or pore-clogging. Farmacy also sells a scented version, but I recommend the fragrance-free one for sensitive, acne-prone skin. <\/p>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/Farmacy-Green-Clean-Cleansing-Balm-Fragrance-free-e5cd7f.jpg\" alt=\"A woman using Farmacy\u2019s Green Clean Fragrance-Free Cleansing Balm.\" height=\"1200\" width=\"1200\"\/>Nothing removes makeup and skin care products from my skin as well as this cleansing balm does, and it leaves behind a soft, hydrated feel.Courtesy Zoe Malin<a href=\"https:\/\/www.amazon.com\/CeraVe-Hydrating-Facial-Cleanser-Fragrance\/dp\/B01MSSDEPK?tag=tretinoinskincareroutinercna343135-20\" data-product-id=\"rcpd44915\" data-aps-asc-tag=\"tretinoinskincareroutinercna343135-20\" data-aps-asin=\"B01MSSDEPK\" rel=\"sponsored noopener noreferrer\" target=\"_blank\" data-testid=\"product-picture-link\" class=\"w-100\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/AMAZON-CeraVe-Hydrating-Facial-Cleanser-Moisturizing-Face-Wash-For-Dry-Skin-Hyaluronic-Acid--Ceramid.png\" alt=\"Cerave Hydrating Facial Cleanser\" height=\"500\" width=\"500\"\/><\/a><\/p>\n<p><strong>Key ingredients:<\/strong> ceramides, hyaluronic acid \u00a0| <strong>Fragrance-free:<\/strong> yes<\/p>\n<p>What we like<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Gentle formula<\/li>\n<li>Noncomedogenic<\/li>\n<li>Pump applicator<\/li>\n<\/ul>\n<p>Something to note<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>May not be good for oily skin<\/li>\n<\/ul>\n<p id=\"anchor-989e59\" class=\"body-graf\">CeraVe\u2019s <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-cleansers-dry-skin-rcna135139\" target=\"_blank\" rel=\"noopener\">cleanser<\/a> is as basic as they come, which is why I use it. It has a creamy, non-foamy feel \u2014 the brand describes it as lotion-like, which I agree with. The fragrance-free cleanser removes any grime left on my face after I wipe off the cleansing balm, and it hydrates my skin with hyaluronic acid, ceramides and glycerin. My face feels so clean that it\u2019s bare after I use it, and that\u2019s how I know I\u2019m ready to continue on with the rest of my routine.<\/p>\n<p><a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-a49bc2\" id=\"anchor-a49bc2\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">Step 2: eye cream<\/a><\/p>\n<p id=\"anchor-73bc3a\" class=\"body-graf\">Do you need to use <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-eye-creams-rcna251683\" target=\"_blank\" rel=\"noopener\">eye cream<\/a>? Absolutely not, says Milam \u2014 many of them don\u2019t add major benefits to your skin. But as long as you apply one that\u2019s purely hydrating and not made with active ingredients like retinol, it can\u2019t hurt. I mainly use eye cream at night because it creates a barrier around my under eyes, reminding me not to apply Tretinoin in that very sensitive area.<\/p>\n<p><a href=\"https:\/\/click.linksynergy.com\/deeplink?id=ucE5BarM2zo&amp;mid=2417&amp;u1=tretinoinskincareroutinercna343135&amp;murl=https%3A%2F%2Fwww.sephora.com%2Fproduct%2Fglossier-full-orbit-hydrating-brightening-smoothing-eye-cream-P509810\" data-product-id=\"rcpd14536\" rel=\"sponsored noopener noreferrer\" target=\"_blank\" data-testid=\"product-picture-link\" class=\"w-100\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/Screenshot-2024-01-19-at-11-21220b.png\" alt=\"Glossier Full Orbit Eye Cream\" height=\"982\" width=\"792\"\/><\/a><\/p>\n<p id=\"anchor-b9c5f9\" class=\"body-graf\">This is one of the only under-eye products I\u2019ve ever been loyal to. I go through multiple tubes a year and never hesitate to re-buy it because it has consistently made my under-eye area less dry, which was an issue I was struggling with after I started Tret, as well as less puffy. The brand also says the cream helps brighten <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-treatment-undereye-circles-rcna258348\" target=\"_blank\" rel=\"noopener\">dark circles<\/a> and smooth out fine lines, but I haven\u2019t noticed those effects as much. The cream has a lightweight, gel-like texture, and it\u2019s made with hydrating ingredients like hyaluronic acid and niacinamide. I apply it under my eyes and by each corner, which reminds me where to not put Tretinoin.<\/p>\n<p><a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-2d6ff6\" id=\"anchor-2d6ff6\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">Step 3: Tretinoin (plus an optional chemical exfoliant on alternate nights)<\/a><\/p>\n<p id=\"anchor-ca9a78\" class=\"body-graf\">It\u2019s best to use a retinoid like Tretinoin at night because sunlight can deactivate it and make it less effective, says Milam. To properly apply Tretinoin, use a pea-size amount and place tiny dots across your face to evenly distribute it, then rub the thin layer into your skin. Avoid sensitive areas that tend to get dry, like the corners of the mouth, nose and lips, as well as too close to the eye. Using too much of Tretinoin makes irritation more likely, so don\u2019t overdo it.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/tretinoin-cream-f34d6e.jpg\" alt=\"A woman applying Tretinoin cream in small dots across her face.\" height=\"1200\" width=\"1200\"\/>Before rubbing in my Tretinoin cream, I put tiny dots all over my face, which ensures that I evenly distribute it.Courtesy Zoe Malin<\/p>\n<p id=\"anchor-872273\" class=\"body-graf\">While they don\u2019t work the same way, Tretinoin and chemical exfoliants lead to similar results, like acne management, improved texture and a brighter tone. Because of this, you don\u2019t necessarily need to use an additional chemical exfoliant if you\u2019re on the medication, says Wechsler. That said, you can add one to your routine on non-Tretinoin nights to help get rid of dead skin cells and reduce flakiness, further unclog pores and enhance radiance, experts told me.  But only do so once your skin builds up a tolerance to the retinoid, and so long as the chemical exfoliant doesn\u2019t cause irritation.<\/p>\n<p><a href=\"https:\/\/www.amazon.com\/Ordinary-Mandelic-Acid-Hyaluronic-30ml\/dp\/B07BGJMNYL?tag=tretinoinskincareroutinercna343135-20\" data-product-id=\"rcpd51903\" data-aps-asc-tag=\"tretinoinskincareroutinercna343135-20\" data-aps-asin=\"B07BGJMNYL\" rel=\"sponsored noopener noreferrer\" target=\"_blank\" data-testid=\"product-picture-link\" class=\"w-100\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/AMAZON-The-Ordinary-Mandelic-Acid-10--Hyaluronic-Acid-Gentle-Exfoliating-Serum-for-Clarity-and-Hydra.jpeg\" alt=\"The Ordinary Mandelic Acid 10% + Hyaluronic Acid\" height=\"500\" width=\"500\"\/><\/a><\/p>\n<p>What we like<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Gently exfoliates<\/li>\n<li>Smooths out skin texture<\/li>\n<li>Hydrating ingredients<\/li>\n<\/ul>\n<p>Something to note<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>May be irritating for some<\/li>\n<li>Not for new Tretinoin users<\/li>\n<\/ul>\n<p id=\"anchor-96e182\" class=\"body-graf\">After five years of being on Tretinoin, I was still getting what I felt like were too many <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-blackhead-treatments-ncna1269989\" target=\"_blank\" rel=\"noopener\">blackheads<\/a> in my T-zone, and my dermatologist gave me two options: upping my Tret concentration or using a gentle chemical exfoliant every other night. I opted for the latter since my skin has responded so well to the medication otherwise. I now use The Ordinary\u2019s mandelic acid serum on nights when I don\u2019t apply Tretinoin, and it\u2019s made a big difference. The lightweight serum is gentle enough that it has never irritated, but effective enough that I don\u2019t notice as many blackheads anymore, and my skin texture is even smoother now. The fragrance-free, fast-absorbing serum is formulated with 10% mandelic acid, which is an AHA, as well as hydrating hyaluronic acid. It has a barely-there feel.<\/p>\n<p><a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-8e7a3d\" id=\"anchor-8e7a3d\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">Step 4: moisturizer<\/a><\/p>\n<p id=\"anchor-0e77e7\" class=\"body-graf\">Like I do in the morning, I apply Kiehl\u2019s Ultra Facial Cream at night to prevent dryness.<\/p>\n<p><a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-364028\" id=\"anchor-364028\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">How to reset your skin barrier while on Tretinoin<\/a><\/p>\n<p id=\"anchor-674f60\" class=\"body-graf\">If your skin ever gets excessively dry, flaky and irritated, you likely need to pause using Tretinoin, as well as products with other strong active ingredients, for a few days. As Foad mentioned above, super dry, irritated skin can lead to breakouts, so don\u2019t push it. Strip back your skin care routine to just the basics: gentle cleanser and moisturizer. Let the skin barrier reset and get back to its baseline, and then slowly reintroduce the retinoid and other products in your regimen.<\/p>\n<p><a href=\"https:\/\/click.linksynergy.com\/deeplink?id=ucE5BarM2zo&amp;mid=2417&amp;u1=tretinoinskincareroutinercna343135&amp;murl=https%3A%2F%2Fwww.sephora.com%2Fproduct%2Fglossier-after-baume-moisture-barrier-recovery-cream-P504794\" data-product-id=\"rcpd25316\" rel=\"sponsored noopener noreferrer\" target=\"_blank\" data-testid=\"product-picture-link\" class=\"w-100\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/Screenshot-2024-06-07-at-11-0a0bdd.png\" alt=\"Glossier After Baume\" height=\"1223\" width=\"1346\"\/><\/a><\/p>\n<p><strong>Volume:<\/strong> 1.7 oz\u00a0| <strong>Lasts for:<\/strong> ~4 months<\/p>\n<p>What we like<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Great for dry skin<\/li>\n<li>Buttery texture<\/li>\n<li>Softens skin<\/li>\n<\/ul>\n<p>Something to note<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>May be greasy for oily skin<\/li>\n<li>Best for overnight use<\/li>\n<\/ul>\n<p id=\"anchor-6f8da5\" class=\"body-graf\">Consider swapping out your usual nighttime moisturizer for a thick <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-barrier-creams-rcna118121\" target=\"_blank\" rel=\"noopener\">barrier cream<\/a> if you\u2019re dealing with Tretinoin-related irritation, says Dr. <a href=\"https:\/\/www.instagram.com\/draegeanchan\/?hl=en\" target=\"_blank\" rel=\"noopener\">Aegean Chan<\/a>, a board-certified dermatologist and dermatopathologist. I reach for Glossier\u2019s fragrance-free After Baume in that situation. It\u2019s so thick and buttery that it\u2019s essentially a paste, and <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-long-lasting-beauty-rcna266025\" target=\"_blank\" rel=\"noopener\">a little goes a long way<\/a> in terms of application \u2014 as it warms up on my skin, it thins out, making it easy to spread across my face. It\u2019s rich and luxurious, and it leaves my skin super dewy, which always makes me feel like there\u2019s a moisturizing shield over it. Because I\u2019m so shiny after I use the After Baume (yes, like a glazed donut), I only apply it at night. When I wake up the next morning, my skin is always much softer, less flaky and more hydrated. <\/p>\n<p><a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-e98449\" id=\"anchor-e98449\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">How to spot treat acne while on Tretinoin<\/a><\/p>\n<p id=\"anchor-01829d\" class=\"body-graf\">The goal of Tretinoin is to ultimately prevent you from getting acne, but you might get a pimple from time to time, or go through a <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/skin-purging-vs-breakouts-rcna261398\" target=\"_blank\" rel=\"noopener\">purge<\/a> when you first start using it (read more about \u201cthe purge\u201d in the FAQ section below). In those cases, don\u2019t throw the kitchen sink at active breakouts. Instead, rely on <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-pimple-patches-rcna248234\" target=\"_blank\" rel=\"noopener\">pimple patches<\/a> and over-the-counter <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-salicylic-acid-products-acne-ncna1274542\" target=\"_blank\" rel=\"noopener\">salicylic acid<\/a> <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-acne-spot-treatments-rcna224753\" target=\"_blank\" rel=\"noopener\">spot treatments<\/a> to calm down the lesions, says Wechsler. Use the spot treatments on nights you\u2019re not using Tretinoin, and only apply a small dot to the pimple, not your whole face. If you\u2019re breaking out very badly, consult your dermatologist, who may prescribe an antibiotic or inject a low-dose steroid into large cysts, says Milam.<\/p>\n<p><a href=\"https:\/\/www.amazon.com\/Mighty-Patch-Hydrocolloid-Absorbing-Pimple\/dp\/B07B4KQVK6?tag=tretinoinskincareroutinercna343135-20\" data-product-id=\"rcpd73057\" data-aps-asc-tag=\"tretinoinskincareroutinercna343135-20\" data-aps-asin=\"B07B4KQVK6\" rel=\"sponsored noopener noreferrer\" target=\"_blank\" data-testid=\"product-picture-link\" class=\"w-100\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/AMAZON-Mighty-Patch-Original-patch-from-Hero-Cosmetics--The-1-Hydrocolloid-Acne-Pimple-Patch-for-Shr.jpeg\" alt=\"Hero Cosmetics The Original Mighty Patch\" height=\"500\" width=\"500\"\/><\/a><\/p>\n<p>What we like<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Successfully sticks on skin<\/li>\n<li>Reduces zit size and height<\/li>\n<li>Prevents picking &amp; popping<\/li>\n<\/ul>\n<p>Something to note<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Visible on skin during wear<\/li>\n<\/ul>\n<p id=\"anchor-8a43e1\" class=\"body-graf\">As someone who had severe cystic acne for years, I\u2019ve covered my face in hundreds of pimple patches at this point, so I\u2019ve tested them all. Hero Cosmetics\u2019 hydrocolloid Mighty Patch is hands-down the best of the best. Once I stick them to my face, they don\u2019t move whatsoever, whether I\u2019m going about my day-to-day life, doing <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-pilates-equipment-apparel-rcna133536\" target=\"_blank\" rel=\"noopener\">Pilates<\/a> or sleeping. They shrink the size and height of inflamed zits by sucking gunk out of them, but most importantly, they prevent me from picking at and <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/is-it-bad-to-pop-your-pimples-rcna155441\" target=\"_blank\" rel=\"noopener\">popping pimples<\/a>, which I\u2019m definitely guilty of. I find <a href=\"https:\/\/www.amazon.com\/Mighty-Patch-Hydrocolloid-Absorbing-Pimple\/dp\/B07B4KQVK6?tag=tretinoinskincareroutinercna343135-20\" rel=\"sponsored noopener\" target=\"_blank\" data-commerce-encoding=\"true\" data-seller-id=\"ncrg916911\">The Original Mighty Patch<\/a> to work best, but if you feel like those are too noticeable during the day, the <a href=\"https:\/\/www.amazon.com\/Mighty-Patch-Invisible-Best-Selling-Award-Winning\/dp\/B07KJS13PK?tag=tretinoinskincareroutinercna343135-20\" rel=\"sponsored noopener\" target=\"_blank\" data-commerce-encoding=\"true\" data-seller-id=\"ncrg916911\">Invisible+ Mighty Patch<\/a> is great, too. <\/p>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/Hero-Cosmetics-The-Original-VS-Invisible-Mighty-Patch-362351.jpg\" alt=\"A woman wearing Hero Cosmetics\u2019 The Original Mighty Patch (right) and the Invisible+ Mighty Patch (left).\" height=\"1200\" width=\"1200\"\/>Hero Cosmetics\u2019 The Original Mighty Patch (right) is more noticeable on my skin compared to the Invisible+ patch (left), but it works better, so I don\u2019t mind wearing it out and about. Courtesy Zoe Malin<a href=\"https:\/\/www.amazon.com\/Mario-Badescu-Drying-Lotion-fl\/dp\/B0017SWIU4?tag=tretinoinskincareroutinercna343135-20\" data-product-id=\"rcpd25054\" data-aps-asc-tag=\"tretinoinskincareroutinercna343135-20\" data-aps-asin=\"B0017SWIU4\" rel=\"sponsored noopener noreferrer\" target=\"_blank\" data-testid=\"product-picture-link\" class=\"w-100\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.europesays.com\/uk\/wp-content\/uploads\/2026\/05\/AMAZON-48ec25.jpg\" alt=\"Mario Badescu Drying Lotion\" height=\"500\" width=\"500\"\/><\/a><\/p>\n<p><strong>Formula type:<\/strong> lotion<\/p>\n<p>What we like<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Easy to apply to small areas<\/li>\n<li>Shrinks zits<\/li>\n<li>Calms inflammation<\/li>\n<\/ul>\n<p>Something to note<\/p>\n<ul class=\"styles_prosConsItems__rVNhO\">\n<li>Pink and chalky lotion<\/li>\n<li>Best for overnight use<\/li>\n<li>Don\u2019t shake bottle<\/li>\n<\/ul>\n<p id=\"anchor-381f01\" class=\"body-graf\">I always keep a bottle of this spot treatment at home in case I need it. On nights I\u2019m not using Tretinoin, I\u2019ll skip my chemical exfoliator and instead put <a href=\"https:\/\/www.amazon.com\/Mario-Badescu-Drying-Lotion-fl\/dp\/B0017SWIU4?tag=tretinoinskincareroutinercna343135-20\" rel=\"sponsored noopener\" target=\"_blank\" data-commerce-encoding=\"true\" data-seller-id=\"ncrg916911\">Mario Badescu\u2019s Drying Lotion<\/a> on any pimples that really need help drying up. It\u2019s made with salicylic acid and sulfur, ingredients that exfoliate and cleanse pores while absorbing excess oil, according to the brand. The treatment also has soothing calamine in it, which is why the lotion is pink and slightly chalky on your skin (another reason I use it at night). I drip a cotton swap in the bottle, making sure it reaches the bottom, and I dab the lotion on each pimple. Overnight, my blemishes always get smaller and less angry.<\/p>\n<p id=\"anchor-572aec\" class=\"body-graf\">There\u2019s a few key rules to abide by while building a skin care routine if you\u2019re on Tretinoin:<\/p>\n<ul id=\"anchor-f32c78\" class=\"break-above body-ul body-list-el\">\n<li><strong>Strip it back when you\u2019re starting the medication: <\/strong>\u201cTretinoin on its own can irritate your skin, so you want to take out all other confounding factors and anything that could make your skin more sensitive,\u201d says Chan. \u201cYou also want to know how well your skin is responding to it without anything else getting in the way.\u201d<\/li>\n<li><strong>Keep it simple: <\/strong>Using too many products at once can cause irritation, so don\u2019t overdo it, says Milam. The less steps your skin care routine has, the better.<\/li>\n<li><strong>Prioritize hydrating, gentle, noncomedogenic products<\/strong>: Dryness is one of the main Tretinoin side effects, so pair the medication with non-irritating products that help restore hydration to the skin using ingredients like ceramides, hyaluronic acid, glycerin and squalane, says Milam. Also, make sure everything you use is noncomedogenic, which means it\u2019s less likely to clog pores and cause breakouts.<\/li>\n<li><strong>Don\u2019t directly combine Tretinoin with other strong active ingredients<\/strong>: Once your skin builds up a tolerance to Tretinoin and you\u2019re not experiencing constant dryness, breakouts and irritation (read more about that in the FAQ section below), you can reintroduce other active ingredients into your routine, like chemical exfoliants, <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-peptides-in-skin-care-rcna257810\" target=\"_blank\" rel=\"noopener\">peptides<\/a> and antioxidants. Just be careful about when and how often you apply them to avoid excess dryness and irritation. For example, if you want to use a vitamin C serum, do so in the morning and apply Tretinoin at night, says Foad. Or if you want to use chemical exfoliants like AHAs and BHAs, do so every other night and alternate with Tretinoin. <\/li>\n<\/ul>\n<p>Frequently asked questions<\/p>\n<p>What is Tretinoin?<\/p>\n<p>Tretinoin (all-trans retinoic acid, to be technical) is a prescription-strength topical retinoid that falls in the vitamin A family, says Chan. It\u2019s one of the most potent and directly active forms of a retinoid \u2014 the skin doesn\u2019t need to convert it into a purer form before using it, which means it works faster and more intensely than over-the-counter retinoids, says Foad. <\/p>\n<p>Tretinoin typically comes in three concentrations: 0.025 percent, 0.05 percent and 0.1 percent, says Foad. Your dermatologist will likely start you on the lowest one, gauge your progress for a few months and adjust from there. The medication is also available in several bases, like a water-based cream and an alcohol-based gel, letting your doctor further customize it to your skin type. For example, cream bases have more moisture than gels, making them best for people with dry skin, says Foad. On the other hand, gels are more drying, so they\u2019re ideal for people with oily skin.<\/p>\n<p>The U.S. Food and Drug Administration approved Tretinoin as an acne treatment in the early 70s, and it was invented even before that, so dermatologists have the largest body of evidence behind it, says Chan. That\u2019s why it\u2019s the gold standard in terms of treating acne, as well as addressing signs of aging. \u201cAny time a new molecule gets developed, its efficacy gets determined by studying it against Tretinoin since there\u2019s the most research around it,\u201d she says.<\/p>\n<p>How does Tretinoin work?<\/p>\n<p>The actual Tretinoin molecule works by binding with retinoic acid receptors inside skin cells and adjusting how they function, says Chan. \u201cTretinoin is resetting the instruction manual for your skin cells or changing out the machinery,\u201d she says. \u201cYou\u2019re not going to get overnight results \u2014 this is a gradual process with long-term benefits.\u201d<\/p>\n<p>Over time, Tretinoin speeds up skin cell turnover and decreases sebum (an oily substance) production to help prevent clogged pores that can lead to acne; gently exfoliates the skin\u2019s surface; and corrects <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/hyperpigmentation-products-for-dark-skin-rcna173674\" target=\"_blank\" rel=\"noopener\">hyperpigmentation<\/a> from acne scars, <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-melasma-treatments-rcna98546\" target=\"_blank\" rel=\"noopener\">melasma<\/a>, sun damage and more, says Wechsler. It also has anti-aging benefits. There\u2019s an enzyme in skin cells called metalloproteinase, which is responsible for collagen breakdown, says Foad. Tretinoin inhibits that enzyme, slowing down collagen breakdown to keep skin supple and improve the appearance of fine lines and wrinkles.<\/p>\n<p>What does Tretinoin treat?<\/p>\n<p data-element-id=\"0855d7\">Dermatologists mainly use Tretinoin to treat acne and address signs of aging like fine lines and wrinkles, but it\u2019s a workhorse, says Chan. It can also treat pseudofolliculitis barbae (a condition that occurs when hair curls back into skin), <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-keratosis-pilaris-treatments-ncna1303451\" target=\"_blank\" rel=\"noopener\">keratosis pilaris<\/a> (small bumps that occur due to keratin buildup) and hyperpigmentation, including melasma, sun damage and acne scars, for example.<\/p>\n<p>What are the most common side effects of Tretinoin?<\/p>\n<p>Below are some of the most common side effects of Tretinoin, a combination of which people often refer to as the \u201cretinoid uglies,\u201d says Chan. Everyone\u2019s experience with the medication is different, so there\u2019s no guarantee you\u2019ll deal with the below, but it\u2019s helpful to know what to expect.<\/p>\n<ul>\n<li>Dryness, since Tretinoin reduces oil production, says Wechsler. Chan says some of her patients get what she calls the \u201cTretinoin beard,\u201d which is dry, flakey skin around the mouth.<\/li>\n<li>Increased skin sensitivity, redness and irritation, which may temporarily make it feel slightly stingy.<\/li>\n<li>Purging, a.k.a. a temporary increase in breakouts that may make you feel like Tretinoin is making your acne worse. That\u2019s totally normal and temporary. \u201cAny pre-acne lesions from clogged pores that are waiting in the wings suddenly speed up and come out at once when you start using Tretinoin,\u201d says Chan. The purge doesn\u2019t happen to everyone, despite what you may see on social media  \u2014 Chan says about 40 to 50 percent of her patients experience it. If you slowly introduce Tretinoin into your skin care routine, you have a lower chance of it happening. <\/li>\n<\/ul>\n<p>Where can you get Tretinoin?<\/p>\n<p>Tretinoin is only available through a prescription. You\u2019ll have to visit a dermatologist in-person or meet with a dermatologist through telemedicine platforms like Walgreens Virtual Healthcare, Goodrx and Amazon One Medical to get the medication.<\/p>\n<p>How often should you use Tretinoin?<\/p>\n<p>If your skin tolerates it, you should use Tretinoin every night and build up to doing so over time, according to the dermatologists I spoke to. But that\u2019s not realistic for everyone: Frequency depends on how long you\u2019ve been using the medication for, your skin type and even the weather. For example, some people need to use Tretinoin less often in the cold, dry winter, or during the summer when they\u2019re constantly exposed to strong sun.<\/p>\n<p>Because irritation is so common, starting slow and building up a tolerance to Tretinoin is important when you first add it to your skin care routine, says Wechsler. She usually has her patients use it one to two nights a week, and, so long as their skin reacts positively, gradually increasing the frequency to every other night or every night. However, you don\u2019t need to use Tretinoin every night for it to be effective, and you should not apply it more than once a day.<\/p>\n<p>How long does it take for Tretinoin to work?<\/p>\n<p>If you\u2019re using Tretinoin to treat acne, it usually takes about six to eight weeks to see results, at which point you\u2019ll likely begin noticing a reduction in breakouts, says Wechsler. If you\u2019re using Tretinoin for anti-aging, it usually takes about six to 12 months to see results, says Chan. \u201cWhen you start Tretinoin, you have to have a no pain, no gain mentality,\u201d she says. \u201cIt\u2019s a long-term investment and a very effective medication, but you\u2019re going to feel like it doesn\u2019t work at first. Then, all of a sudden, the clouds part and the angels sing.\u201d<\/p>\n<p>How long should you use Tretinoin for?<\/p>\n<p>How long you should use Tretinoin varies per person, says Wechsler. The only time you absolutely can\u2019t use it is while <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-pregnancy-safe-skin-care-rcna100065\" target=\"_blank\" rel=\"noopener\">pregnant<\/a>. \u201cThere\u2019s a lot of people who will fall in love with it for its anti-acne properties, and then consistently stay with it for its anti-aging properties,\u201d says Wechsler. But there\u2019s also people who only use it to get through a specific period of their life, or start and stop it depending on their skin issues and goals. Discuss your personal Tretinoin timeline with a dermatologist.<\/p>\n<p>Should you stop using Tretinoin before cosmetic procedures?<\/p>\n<p>Yes, you should stop using Tretinoin about five days before any sort of cosmetic procedure, including exfoliating facials, chemical peels, microneedling and laser treatments, says Foad. Waxing also falls into this category. If you\u2019re getting your eyebrows or lip waxed, for example, don\u2019t use Tretinoin for five days prior \u2014 the medication makes your skin barrier thinner since it increases cell turnover, and hot wax could leave a burn, says Foad.<\/p>\n<p>Can you use the retinol sandwich method with Tretinoin?<\/p>\n<p>Yes, you can use the <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/retinol-sandwiching-asked-derms-viral-trend-rcna202424\" target=\"_blank\" rel=\"noopener\">retinol sandwich method<\/a> with Tretinoin, says Foad. That involves applying a thin layer of moisturizer and layering Tretinoin on top \u2014 the moisturizer creates a barrier between the skin and the medication, which essentially makes it less strong and reduces the potential for irritation. It\u2019s best to use the retinol sandwich method when your skin is building up a tolerance to Tretinoin and slowly eliminating it afterward.<\/p>\n<p>Can you use Tretinon while pregnant and breastfeeding?<\/p>\n<p>No, you cannot use Tretinoin (or any other retinoid) while pregnant, says Chan. You can, however, use it while breastfeeding, says Milam.<\/p>\n<p><a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-fbac71\" id=\"anchor-fbac71\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">Meet our dermatology experts<\/a><\/p>\n<p id=\"anchor-85ed24\" class=\"body-graf\">At NBC Select, we work with experts who have specialized knowledge and authority based on relevant training and\/or experience. We also ensure that all expert advice and recommendations are made independently and with no undisclosed financial conflicts of interest.<\/p>\n<ul id=\"anchor-60dadd\" class=\"break-above body-ul body-list-el\">\n<li>Dr. <a href=\"https:\/\/nyulangone.org\/doctors\/1316300296\/emily-c-milam\" target=\"_blank\" rel=\"noopener\"><strong>Emily Milam<\/strong><\/a> is a board-certified dermatologist at NYU Langone Health.<\/li>\n<li>Dr. <a href=\"https:\/\/www.monadermatology.com\/team-member\/about-mona\/\" target=\"_blank\" rel=\"noopener\"><strong>Mona Foad<\/strong><\/a> is a board-certified dermatologist and founder of <a href=\"https:\/\/www.monadermatology.com\" target=\"_blank\" rel=\"noopener\">MONA Dermatology<\/a>.<\/li>\n<li>Dr. <a href=\"https:\/\/dramywechsler.com\" target=\"_blank\" rel=\"noopener\"><strong>Amy Wechsler<\/strong><\/a> is a board-certified dermatologist and psychiatrist who\u2019s also the co-founder and CEO of <a href=\"https:\/\/spotlessclinics.com\" target=\"_blank\" rel=\"noopener\">Spotless Clinics<\/a>.<\/li>\n<li>Dr. <a href=\"https:\/\/www.instagram.com\/draegeanchan\/?hl=en\" target=\"_blank\" rel=\"noopener\"><strong>Aegean Chan<\/strong><\/a> is a board-certified dermatologist and dermatopathologist.<\/li>\n<\/ul>\n<p><a href=\"http:\/\/www.nbcnews.com\/select\/shopping\/tretinoin-skin-care-routine-rcna343135#anchor-fa82b3\" id=\"anchor-fa82b3\" class=\"scrollLink\" target=\"_blank\" rel=\"noopener\">Why trust NBC Select?<\/a><\/p>\n<p id=\"anchor-ff46dd\" class=\"body-graf\">I\u2019m a <a href=\"https:\/\/www.nbcnews.com\/author\/zoe-malin-ncpn1232165\" target=\"_blank\" rel=\"noopener\">reporter at NBC Select<\/a> who has covered skin care for over five years, including topics like <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-ingrown-hair-treatments-prevention-rcna101598\" target=\"_blank\" rel=\"noopener\">ingrown hair<\/a>, sunburns, <a href=\"https:\/\/www.nbcnews.com\/select\/shopping\/best-products-razor-burns-rcna245058\" target=\"_blank\" rel=\"noopener\">razor burn<\/a>, tinted sunscreen and sunscreen for acne-prone skin. For this article, I interviewed four dermatologists about how to properly incorporate Tretinoin into your skin care routine, as well as side effects, benefits and other important information about the retinoid. I\u2019ve been using Tretinoin for six years, so I also shared my personal experience with the medication and what products support my acne-prone, sensitive skin.<\/p>\n<p id=\"anchor-fa51c0\" class=\"endmark body-graf\"><strong>Catch up on NBC Select\u2019s in-depth coverage of <\/strong><a href=\"https:\/\/www.nbcnews.com\/select\/tech-tools\" target=\"_blank\" rel=\"noopener\"><strong>tech and tools<\/strong><\/a><strong>, <\/strong><a href=\"https:\/\/www.nbcnews.com\/select\/wellness\" target=\"_blank\" rel=\"noopener\"><strong>wellness<\/strong><\/a><strong> and more, and follow us on <\/strong><a href=\"https:\/\/www.facebook.com\/NBCSelect\" target=\"_blank\" rel=\"noopener\"><strong>Facebook<\/strong><\/a><strong>, <\/strong><a href=\"https:\/\/www.instagram.com\/nbcselect\/\" target=\"_blank\" rel=\"noopener\"><strong>Instagram<\/strong><\/a><strong>, <\/strong><a href=\"https:\/\/twitter.com\/nbcselect\" target=\"_blank\" rel=\"noopener\"><strong>Twitter<\/strong><\/a><strong> and <\/strong><a href=\"https:\/\/www.tiktok.com\/@nbcselect\" target=\"_blank\" rel=\"noopener\"><strong>TikTok<\/strong><\/a><strong> to stay up to date.<\/strong> <\/p>\n<p><script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script><script async src=\"\/\/www.instagram.com\/embed.js\"><\/script><script async src=\"\/\/www.tiktok.com\/embed.js\"><\/script><\/p>\n","protected":false},"excerpt":{"rendered":"When my dermatologist prescribed me Tretinoin for cystic acne six years ago, I only had one question: How&hellip;\n","protected":false},"author":2,"featured_media":942602,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4315],"tags":[105,4326,16,15],"class_list":{"0":"post-942601","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-medication","8":"tag-health","9":"tag-medication","10":"tag-uk","11":"tag-united-kingdom"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@uk\/116530306473569027","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/942601","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/comments?post=942601"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/posts\/942601\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media\/942602"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/media?parent=942601"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/categories?post=942601"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/uk\/wp-json\/wp\/v2\/tags?post=942601"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}