A woman was killed in a hit-and-run in Brooklyn, a man was left in critical condition after being mowed down by a driver in the Bronx and a motorcycle rider died after crashing on the Lower East Side, all within an eight-hour span in the city, police said.

On Saturday around 7:30 a.m., a 28-year-old woman was walking in the crosswalk at 55th St. at Third Ave. in Sunset Park when she was struck by a Cadillac Escalade heading southbound on Third Ave., cops said. She suffered severe head and body trauma. EMS removed her to NYU Langone Hospital — Brooklyn in critical condition, where she was later pronounced dead.

The NYPD Highway Patrol investigates after a woman was fatally struck by a Cadillac Escalade on Third Ave. in Sunset Park on Saturday.

Theodore Parisienne / New York Daily News

The NYPD Highway Patrol investigates after a woman was fatally struck by a Cadillac Escalade on Third Ave. in Sunset Park on Saturday. (Theodore Parisienne / New York Daily News)

Police are withholding the victim’s name pending family notification.

The driver did not stay at the scene and there has been no arrest. The NYPD Highway Collision Investigation Squad is investigating.

Earlier Saturday, around 2:20 a.m., a motorcycle rider fatally crashed on the southbound FDR Drive’s Exit 2 at the Brooklyn Bridge. Police said Hasan Ibrahim, 25, of Bath Beach, Brooklyn, was riding a Honda CBR500R when he failed to navigate the roadway and slammed into a concrete barrier. EMS transported him to Bellevue Hospital in critical condition, but he could not be saved.

A motorcycle rider fatally crashed on the southbound FDR near the Brooklyn Bridge early Saturday.

Theodore Parisienne / New York Daily News

A motorcycle rider fatally crashed on the southbound FDR near the Brooklyn Bridge early Saturday. (Theodore Parisienne / New York Daily News)

In addition, on Friday just before midnight, a 53-year-old man was grievously injured when he was hit by a 31-year-old woman driving a Nissan Altima at Boston Road and Corsa Ave. in Williamsbridge in the Bronx, police said. Cops said the driver was heading eastbound with the green light on Boston Road as she approached the intersection as the pedestrian was attempting to cross the street.

Blood is seen on the road after a 53-year-old man was grievously injured when he was hit by the driver of a Nissan Altima at Boston Road and Corsa Ave. in the Bronx on Friday.

Theodore Parisienne / New York Daily News

Blood is seen on the road after a 53-year-old man was critically injured when he was hit by the driver of a Nissan Altima at Boston Road and Corsa Ave. in the Bronx on Friday. (Theodore Parisienne / New York Daily News)

The man, suffering head and body trauma, was taken to Jacobi Hospital, where he was in critical condition. The driver stayed at the scene and was not arrested.