Detectives found prescription medication for depression and epilepsy in the Las Vegas home of Midtown mass shooter Shane Tamura, sources tell The Post.

The discovery was made while executing a search warrant at his Sin City apartment Tuesday, a day after he stormed a New York skyscraper with an AR-style rifle, killing four people and wounding one before turning the gun on himself.

Also found in the home was a note in which Tamura, 27, revealed he felt like a “complete disappointment” to his parents, including his retired cop father, sources told The Post.

Shane Tamura killed four people and wounded one before turning the gun on himself in a New York City skyscraper. AP

Prescription medication for depression and epilepsy were found in Tamura’s Las Vegas home, sources tell The Post. Toby Canham for NYPost.com

David Becker

Note found on Shane Tamura’s body. Obtained by NY Post

Blood-stained AR-15 rifle. Obtained by the NY Post

While previously searching his car, investigators found a Colt Python .357-caliber handgun, along with a rifle case, ammunition and the migraine medication Sumatriptan.

Also found was a note in which Tamura, 27, revealed he felt like a “complete disappointment” to his parents, including his retired cop father, sources told The Post.

Tamura had been targeting the NFL, which has its headquarters at 345 Park Avenue in Manhattan, blaming the league for what he alleges is CTE — a degenerative brain disease brought on by repeated blows to the head.

A note found on his body after the shooting expressed admiration for doctors specializing in CTE as well as a documentary linking the NFL to the prevalence of the disease among its players.

Tamura was a star running back in high school, but never played football at the collegiate or professional level.

A suicide note found on Tamura after the rampage also included a plea to “study my brain” after his death, as CTE can only be diagnosed post-mortem.

While previously searching his car, investigators found a Colt Python .357-caliber handgun, along with a rifle case, ammunition and the migraine medication Sumatriptan. Obtained by the NY Post

Notes found on Shane Tamura’s body, including apologies and a computer password. Obtained by NY Post

Also found was a note in which Tamura, 27, revealed he felt like a “complete disappointment” to his parents, including his retired cop father, sources told The Post. Xinhua/Shutterstock

The mad killer’s brain will in fact be examined as part of his autopsy, NYC chief medical examiner Dr. Jason Graham said at a press briefing that a neuropathology expert was in the process of carrying out “additional testing” on the gunman’s gray matter.

Tamura’s former high school football coach, Walter Roby, told The Post that he couldn’t recall the shooter sustaining any head injuries on the field.