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Five NFL games we can’t wait to watch in the 2025 season

The schedule for the 2025 NFL season has been released. Here are a few games on our must-watch list.

The NFL Week 1 schedule (and the 2025 NFL season) kicks off with a Thursday Night Football game between the Philadelphia Eagles and Dallas Cowboys at Lincoln Financial Field in Philadelphia.

Here’s what you need to know before the NFL Week 1 Thursday Night Football matchup, including time, TV channel, streaming information, NFL Week 1 announcers, NFL Week 1 odds, NFL Week 1 picks and NFL Week 1 predictions for the game on Sept. 4.

The Eagles are the defending Super Bowl Champions and are considered among the favorites in early Super Bowl odds for the 2025-2026 season, but the Cowboys hope to challenge Philadelphia in the NFC East and NFC this season.

NFL Week 1 picks: Cowboys vs Eagles | Chiefs vs Chargers | Buccaneers vs Falcons | Bengals vs Browns | Dolphins vs Colts | Panthers vs Jaguars | Raiders vs Patriots | Cardinals vs Saints | Steelers vs Jets | Giants vs Commanders | Titans vs Broncos | 49ers vs Seahawks | Lions vs Packers | Texans vs Rams | Ravens vs Bills | Vikings vs Bears | The Republic’s score predictions

Watch Cowboys at Eagles with FUBO (free trial)

What time is Thursday Night Football?

The Cowboys vs Eagles game is scheduled to begin at 5:20 p.m. MST, 8:20 p.m. ET.

What channel is Thursday Night Football on?

While Thursday Night Football usually streams exclusively on Amazon, the NFL Week 1 matchup between the Cowboys and Eagles will be shown on NBC.

How can I stream Thursday Night Football?

Cowboys at Eagles can be streamed on Peacock, NBC’s streaming service, as well as other streaming services that carry NBC, including FUBO (free trial).

Who are the announcers for Thursday Night Football?

Mike Tirico will have the play-by-play call for the Eagles-Cowboys game, with Cris Collinsworth as the analyst.

Who is the favorite in Thursday Night Football odds?

The Eagles are a 7-point favorite over the Cowboys in NFL Week 1 odds for the game, courtesy of BetMGM Sportsbook.

Philadelphia is -300 on the moneyline, while Dallas is +240.

The over/under (point total) is set at 46 points.

Who will win on Thursday Night Football?

The Arizona Republic is predicting a 24-21 win for the Eagles over the Cowboys in the Thursday Night Football showdown.

Other sites’ NFL Week 1 picks and NFL Week 1 predictions also seem to favor the Eagles winning the TNF game over the Cowboys tonight, but some are taking Dallas with the points over Philadelphia in the first game on the Week 1 NFL schedule.

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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