Four people have been badly injured and a girl has died in a two-vehicle crash on Thursday.

A ute and a station wagon collided at the intersection of the Great Southern Hwy and Robinson Rd at Woodanilling, about three hours southeast of Perth, at 1.30pm.

The 12-year-old girl died at the scene, WA Police said.

Four other people were airlifted to Royal Perth Hospital with serious injuries.

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The ute driver only suffered minor physical injuries and was taken to Katanning Hospital.

Investigations are ongoing and anyone who saw the crash, a Mitsubishi Triton utility, or aHonda CR-V station wagon travelling in the area before the crash, are urged to contact Crime Stoppers.

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