The Indianapolis Colts (5-1) visit the Los Angeles Chargers (4-2) at SoFi Stadium in Inglewood for a Week 7 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, October 19, including live updated odds and injury report news.
Chargers vs. Colts live odds, moneyline, over/under
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Chargers vs. Colts picks against the spread
Jon Hoefling: Indianapolis Colts (+1.5)
The Chargers have looked all out of whack ever since Omarion Hampton went down. They won’t be able to keep up with the Colts. I’d take the Colts moneyline, perhaps even take them as 2.5-point favorites.
Jordan Mendoza: Indianapolis Colts (+1.5)
The way the Colts offense has been, it’s hard to envision anyone being able to stop them. The last time they were in Los Angeles, they lost a heartbreaker to the Rams. Indianapolis changes fortunes with another solid performance by Daniel Jones.
Tyler Dragon: Los Angeles Chargers (-1.5)
Is it time to start believing in the Colts? The Colts would be the top seed in the AFC if the playoffs started today. The Colts lost to the Rams in LA. I think they go 0-2 at SoFi Stadium.
Lorenzo Reyes: Indianapolis Colts (+1.5)
The Chargers are banged up at running back, but they’ve played games unnecessarily close over the past few weeks. Frankly, they lucked out against the Dolphins. The Indianapolis offense has been stellar, so I could see this being a spot for Indy on the moneyline.
Christopher Bumbaca: Los Angeles Chargers (-1.5)
The Colts should have won at SoFi last time they played there, their lone loss of the season which came against the Rams. But SoFi will be Indy’s house of horrors in 2025 with another loss.
Blake Schuster: Los Angeles Chargers (-1.5)
I finally trusted the Colts to cover last week and it came back to bite me. I can’t get fooled in consecutive weeks.
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