Diane Ladd’s cause of death was acute on chronic hypoxic respiratory failure, PEOPLE reported Monday.
The Academy Award-nominated actress died Nov. 3, her daughter Laura Dern announced.
On Monday, PEOPLE obtained a death certificate, which notes notes she had interstitial lung disease, which had been going on for years. Esophageal dysmotility was listed as another significant contributing condition.
Dern released a statement earlier this month, announcing the death.
“My amazing hero and my profound gift of a mother passed with me beside her this morning at her home in Ojai, California,” Dern said in a statement. “She was the greatest daughter, mother, grandmother, actress, artist and empathetic spirit that only dreams could have seemingly created. We were blessed to have her. She is flying with her angels now.”
Ladd’s breakout role came as Flo, blunt waitress, in Martin Scorsese‘s 1974 movie “Alice Doesn’t Live Here Anymore.” The role earned her an Academy Award nomination. Oscar nominations also came with her roles in She also received supporting actress nods in the early 1990s for David Lynch’s “Wild at Heart” and Martha Coolidge’s “Rambling Rose,” both of which co-starred Dern.
Per the Cleveland Clinic, hypoxic respiratory failure occurs when there isn’t enough oxygen in the blood, which is often caused by a lung condition.
A native of Laurel, Mississippi, Ladd was born Rose Diane Ladner and was apparently destined to stand out. In her 2006 memoir, “Spiraling Through the School of Life,” she remembered being told by her great-grandmother that she would one day in “front of a screen” and would “command” her own audiences. Before “Alice Doesn’t Live Here Anymore,” she had been working in television since the 1950s, when she was in her early 20s, with shows including “Perry Mason,” “Gunsmoke” and “The Big Valley.”
By the mid-1970s, she had lived out her fate well enough to tell The New York Times that no longer denied herself the right to call herself great.
Ladd was married three times, and divorced twice — from Bruce Dern and from William A. Shea, Jr. In 1976, around the time her second marriage ended, she told the Times that neither of her husbands knew “how to show love.”
The Associated Press contributed to this report.
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