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Longevity has officially entered its evidence-backed era.
What was once the domain of biohackers and academic labs is now a fast-growing category of everyday wellness, driven by a simple but demanding consumer question: What actually works…and how? The answer increasingly points to cellular health, specifically the role of NAD⁺ (nicotinamide adenine dinucleotide), a molecule essential for energy production, DNA repair, and metabolic function that naturally declines with age.
NMN (nicotinamide mononucleotide) has emerged as one of the most closely studied NAD⁺ precursors, but not all NMN supplements are created equal. Differences in dosage, formulation, purity and scientific oversight matter substantially. For readers trying to navigate the space, separating marketing noise from legitimate research is the real challenge.
This is where Wonderfeel positions itself differently. Rather than treating longevity as a trend, the brand frames it as a translation problem: how to take rigorous, peer-reviewed science and turn it into something usable, understandable, and safe for everyday life.
Wonderfeel
Relevance rather than minimal compliance. The product delivers a 900 milligram dose of NMN, a level aligned with amounts studied in human clinical trials, which is an important distinction in a market where underdosed products are common.
The formulation was engineered by Andrew Salzman, a Harvard-affiliated MD, professor, and scientist with nearly three decades of research experience in NAD biology and cellular health, and more than 170 peer-reviewed publications. Under his direction, Wonderfeel Youngr pairs NMN with a targeted antioxidant matrix designed to address oxidative stress alongside NAD⁺ decline:
- Ergothioneine (from mushrooms), which is studied for cellular protection
- Hydroxytyrosol (from olive fruit), which is associated with cardiovascular and mitochondrial support
- Resveratrol, one of the most researched polyphenols in longevity science
- Vitamin D3 (100% DV) for immune and systemic health support
According to Wonderfeel’s scientific leadership, the goal is not to chase a single “miracle molecule,” but to support the broader biological systems involved in aging. In Salzman’s published work and public commentary, he consistently emphasizes that NAD⁺ metabolism, oxidative stress, and cellular resilience are interconnected processes — an approach reflected directly in the Youngr formulation.
At the top of the NMN landscape sits Wonderfeel Youngr, a patented formula designed around clinical
What to look for in a high-quality NMN supplement
Using Wonderfeel as a benchmark, several criteria stand out when evaluating the best NMN supplements on the market:
Clinically relevant dosing: Many products contain NMN, but few disclose or reach doses comparable to those used in human studies.
Formulation transparency: Ingredient sourcing, synergy, and rationale should be clear — not hidden behind proprietary blends without explanation.
Scientific leadership and accountability: Products developed with direct involvement from researchers actively publishing in the field signal a higher standard of rigor.
What’s beyond the capsule: Longevity is not just supplementation. Brands that invest in education and science communication help consumers make informed, sustainable decisions.
Wonderfeel places notable emphasis on this final point, building an educational ecosystem around its products to make complex longevity science accessible without oversimplifying it.
The verdict
NMN remains one of the most promising areas in longevity research, but effectiveness depends on how seriously a product treats the underlying science. With its high-dose, clinically informed formulation and direct oversight from a leading NAD researcher, Wonderfeel Youngr stands out as a reference point for what an evidence-driven NMN supplement can look like today.
As the longevity category continues to mature, the brands that lead will be those that respect both the science and the consumer’s intelligence. Wonderfeel’s approach suggests that the future of aging well is not about hype but about precision, transparency, and adding life to the years we already have.
This article was written by Kendall Cornish, New York Post Commerce Editor & Reporter. Kendall, who moonlights as a private chef in the Hamptons for New York elites, lends her expertise to testing and recommending cooking products – for beginners and aspiring sous chefs alike. Simmering and seasoning her way through both jobs, Kendall dishes on everything from the best cookware for your kitchen to cooking classes that will level-up your skills to new dinnerware to upgrade your holiday hosting. Prior to joining the Post’s shopping team in 2023, Kendall previously held positions at Apartment Therapy and at Dotdash Meredith’s Travel + Leisure and Departures magazines.