At least one person was killed when a gas explosion sparked a massive, four-alarm blaze on the top floors of a high-rise apartment building in the Bronx early Saturday morning.

Flames shot out of the 16th floor of the NYCHA building at 3485 Bivonia Street shortly after midnight as firefighters worked to evacuate over 150 homes in the building, officials told reporters.

A civilian, who has not been identified, was pronounced dead and 14 others were wounded, including one in critical condition, FDNY Chief Kathleen Knuth said.

Firefighters battled a blaze early Saturday on the top two floors of a high-rise apartment in New York City, according to fire officials. Christopher Sadowski

All injured victims were transported to area hospitals.

Flames and thick smoke were captured spewing out of multiple windows on the top floors of the building, according to video captured by The Post.

Another haunting image captured a resident hanging out of a window on the top floor waving a bed sheet.

Over 230 first responders from 75 units responded to the multi-alarm blaze as temperatures dropped to the low teens and below around New York City.

A person holding onto a bed sheet hangs out a window on the top floor of the building. Christopher Sadowski

The 4-alarm fire in the Bronx started shortly after midnight and spread to multiple apartments in the 17-story building, according to a statement from the New York City Fire Department. Christopher Sadowski

Smoke billows out of the building as firefighters battle the deadly blaze. Christopher Sadowski

“It was a very, very difficult night, on a very cold night, which caused even more difficulty. The men and women of the fire department and all the first responders of our department did a terrific job putting these fires out, couldn’t have thanked them more,” FDNY Commissioner Lillian Bonsignore told reporters.

Bonsignore said there was an investigation into the smell of gas in the building 15 minutes before the explosion occurred.

“It’s a terrible tragedy, we are sending our thoughts to everyone involved,” Leila Bozorg, deputy mayor for housing and planning, said.

Over 230 first responders from 75 units responded to the multi-alarm blaze as temperatures dropped to the low teens and below around New York City. Christopher Sadowski

Smoke pours out of a window after a fire in the Bronx. Christopher Sadowski

New York City Emergency Management Commissioner Zach Iscol warned of the importance of fire safety, especially with an impending catastrophic blizzard from Winter Storm Fern.

“If this happened tomorrow during the snowstorm it would’ve been a much, much different event,” Iscol said.

The cause of the gas explosion was still under investigation, according to officials.