Four people were transported to the hospital Saturday night following a serious injury collision near the intersection of F Street and 15th Street in Downtown San Diego, according to the San Diego Police Department.

One of the patients transported to the hospital was in critical condition following the crash.

The intersection will be shut down for an unknown period of time and police ask that drivers avoid the area.

Those traveling into downtown from the westbound SR-94 exit may be impacted, according to authorities.

The crash involved a total of three vehicles, and one person was arrested on suspicion of DUI.