TAMPA, Fla. (WFLA)— These drugs fall into a class known as GLP-1s, mimicking a natural hormone that helps regulate blood sugar, slows how quickly food leaves the stomach, and signals the brain that you’re full.
“I would say in this practice, probably 70% of my patients are on this medication in some way or form,” said Dr. Luke Williams.
Now, a newer medication, tirzepatide, is gaining momentum. Unlike earlier options, it targets two hormones instead of one.
“It works on the gut… slowing motility. But it also works in the brain for satiety—so you feel full and calm down the food chatter,” Williams explained.
Doctors say the impact can go beyond the scale. Some patients are seeing long-term success, including improved blood sugar levels and reduced reliance on medications like insulin or metformin.
Once patients reach their goal weight, the journey doesn’t necessarily end.
“You kind of go on a maintenance dose,” Williams said, noting some patients transition to lower doses to help sustain results. Research suggests many people may need to stay on the medication for at least a year to maintain weight loss.
But there are risks, especially at higher doses.
“At higher doses, you can have extreme side effects like bowel obstructions,” Williams warned.
That’s why medical supervision is critical. Experts caution against turning to unregulated online sources, which can pose serious health risks.
Most of these medications are taken as a weekly injection just under the skin. There are also pill versions available, though doctors say they may work slightly differently in how they’re absorbed.
Bottom line: while these drugs can be highly effective, and even life-changing, they’re not a quick fix. Doctors say safe, long-term success depends on proper dosing, monitoring, and ongoing medical care.