• School of Medicine, Cardiff University, Cardiff, UK

    Matthew Bracher-Smith, Julie Williams, Nicola Denning, Alun Meggy & Valentina Escott-Price

  • Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK

    Matthew Bracher-Smith, Peter Holmans, Atahualpa Castillo, Julie Williams, Rebecca Sims & Valentina Escott-Price

  • BIO3 – Systems Medicine, Department of Human Genetics, KU Leuven, Leuven, Belgium

    Federico Melograna & Kristel Van Steen

  • Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom

    Brittany Ulm, Najaf Amin & Cornelia van Duijn

  • Centre for Artificial Intelligence in Precision Medicine, University of Oxford, Oxford, United Kingdom

    Brittany Ulm, Alejo J. Nevado & Cornelia van Duijn

  • Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ – U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France

    Céline Bellenguez, Benjamin Grenier-Boley, Philippe Amouyel & Jean-Charles Lambert

  • BIO3 – Systems Genetics, GIGA-R Molecular and Computational Biology, University of Liege, Liege, Belgium

    Federico Melograna, Diane Duroux & Kristel Van Steen

  • Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands

    Betty M. Tijms, Marc Hulsman, Sven van der Lee, Yolande A. L. Pijnenburg, Henne Holstege, Philip Scheltens, Wiesje van der Flier, Iris Jansen, Sven van der Lee, Marc Hulsman & Niccolo Tesí

  • Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije University, Amsterdam, The Netherlands

    Betty M. Tijms, Marc Hulsman, Sven van der Lee, Iris Jansen, Sven van der Lee & Danielle Posthuma

  • Research Center and Memory Clinic, ACE Alzheimer Center Barcelona. Universitat Internacional de Catalunya, Catalunya, Spain

    Itziar de Rojas

  • Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain

    Itziar de Rojas

  • Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

    Rafael Campos-Martin & Alfredo Ramirez

  • Estudios en Neurociencias y Sistemas Complejos (ENyS) CONICET-HEC-UNAJ, Buenos Aires, Argentina

    Rafael Campos-Martin

  • Complex Genetics of Alzheimer’s Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium

    Fahri Küçükali, Kristel Sleegers & Jasper Van Dongen

  • Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium

    Fahri Küçükali & Kristel Sleegers

  • German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany

    Oliver Peters & Josef Priller

  • Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Psychiatry and Psychotherapy, Hindenburgdamm 30, 12203, Berlin, Germany

    Oliver Peters

  • German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany

    Anja Schneider, Michael Wagner, Frank Jessen & Alfredo Ramirez

  • Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany

    Anja Schneider

  • Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany

    Martin Dichgans

  • German Center for Neurodegenerative Diseases (DZNE), Munich, Germany

    Martin Dichgans

  • Munich Cluster for Systems Neurology (SyNergy), Munich, Germany

    Martin Dichgans

  • Department of Psychiatry and Psychotherapy, Comprehensive Center for Clinical Neurosciences and Mental Health (C3NMH), Medical University of Vienna, Vienna, Austria

    Dan Rujescu

  • Department of Psychiatry and Psychotherapy, LVR-Klinikum Essen, University of Duisburg-Essen, Germany Medical Faculty, Essen, Germany

    Norbert Scherbaum

  • Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital of Würzburg, Würzburg, Germany

    Jürgen Deckert

  • Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, 04103, Leipzig, Germany

    Steffi Riedel-Heller

  • Department of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, Faculty Mannheim, University of Heidelberg, Heidelberg, Germany

    Lucrezia Hausner

  • Alzheimer’s Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic of Barcelona, Fundació Recerca Clinic Barcelona- Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), and University of Barcelona, Barcelona, Spain

    Laura Molina-Porcel

  • Neurological Tissue Bank – Biobank, Hospital Clinic-FRCB-IDIBAPS, Barcelona, Spain

    Laura Molina-Porcel

  • German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany

    Emrah Düzel

  • Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany

    Emrah Düzel

  • Center for Cognitive Disorders, Department of Psychiatry and Psychotherapy, Technical University of Munich, School of Medicine and Health, Klinikum rechts der Isar, Munich, Germany

    Timo Grimmer

  • Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany

    Jens Wiltfang & Jonathan Vogelgsang

  • German Center for Neurodegenerative Diseases (DZNE), Goettingen, Germany

    Jens Wiltfang

  • Medical Science Department, iBiMED, Aveiro, Portugal

    Jens Wiltfang

  • Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany

    Stefanie Heilmann-Heimbach, Per Hoffmann & Markus M. Nöthen

  • Institute for Urban Public Health, University Hospital of University Duisburg-Essen, Essen, Germany

    Susanne Moebus

  • 1st Department of Neurology, Medical school, Aristotle University of Thessaloniki, Thessaloniki, Makedonia, Greece

    Thomas Tegos, Tsolaki Magda, Tsolaki Anthoula & Tegos Thomas

  • Taub Institute for Research in Alzheimer’s Disease and the Aging Brain, The Gertrude H. Sergievsky Center, Depatment of Neurology, Columbia University, New York, NY, USA

    Nikolaos Scarmeas

  • 1st Department of Neurology, Aiginition Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece

    Nikolaos Scarmeas

  • Sant Pau Memory Unit, Institut de Recerca Sant Pau, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain

    Oriol Dols-Icardo, Daniel Alcolea, Rafael Blesa, Laura Cervera-Carles, Jordi Clarimon, Juan Fortea & Alberto Lleó

  • CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain

    Oriol Dols-Icardo, Fermin Moreno, Jordi Pérez-Tur, María J. Bullido, Mercè Boada, Pablo Mir, Jose María García-Alberca, Eloy Rodriguez-Rodriguez, Pascual Sánchez-Juan, Agustín Ruiz, Victoria Fernández, Amanda Cano, Carla Abdelnour, Daniel Alcolea, Montserrat Alegret, Rafael Blesa, Mercè Boada, Dolores Buiza-Rueda, Miguel Calero, Laura Cervera-Carles, Jordi Clarimon, Josep Blázquez, Juan Fortea, Ana Frank-García, Jose Maria García-Alberca, Isabel Hernández, Carmen Lage, Alberto Lleó, Adolfo Lopez de Munain, Marta Marquié, Angel Martín Montes, Miguel Medina, Adelina Orellana, Maria Capdevila, Alberto Rábano, Maitée Rosende-Roca, Fernando García-Gutierrez, Pascual Sánchez-Juan, Lluís Tárraga, Sergi Valero & Miren Zulaica

  • Department of Neurology. Hospital Universitario Donostia, San Sebastian, Spain

    Fermin Moreno

  • Neurosciences Area, Instituto Biogipuzkoa, San Sebastian, Spain

    Fermin Moreno

  • Unitat de Genètica Molecular, Institut de Biomedicina de València-CSIC, Valencia, Spain

    Jordi Pérez-Tur

  • Centro de Biología Molecular Severo Ochoa (UAM-CSIC), Madrid, Spain

    María J. Bullido

  • Instituto de Investigacion Sanitaria ‘Hospital la Paz’ (IdIPaz), Madrid, Spain

    María J. Bullido, Ana Frank-García & Angel Martín Montes

  • Universidad Autónoma de Madrid, Madrid, Spain

    María J. Bullido

  • Fundació Docència i Recerca MútuaTerrassa, Terrassa, Barcelona, Spain

    Pau Pastor

  • Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain

    Pau Pastor, Ignacio Alvarez & Mónica Diez-Fairen

  • Alzheimer’s disease and other cognitive disorders unit. Service of Neurology. Hospital Clínic of Barcelona. Institut d’Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain

    Raquel Sánchez-Valle

  • Laboratorio de Genética. Hospital Universitario Central de Asturias, Oviedo, Spain

    Victoria Álvarez & Irene Rosas Allende

  • Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Asturias, Spain

    Victoria Álvarez & Irene Rosas Allende

  • ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain

    Mercè Boada

  • Research Center and Memory clinic. ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain

    Pablo García-González & Raquel Puerta

  • Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain

    Pablo Mir & Dolores Buiza-Rueda

  • Unidad Clínica de Enfermedades Infecciosas y Microbiología. Hospital Universitario de Valme, Sevilla, Spain

    Luis M. Real, Anaïs Corma-Gómez, Marta Fernández-Fuertes, Juan Macías & Juan A. Pineda

  • Depatamento de Especialidades Quirúrgicas, Bioquímica e Inmunología. Facultad de Medicina. Universidad de Málaga, Málaga, Spain

    Luis M. Real & Jose María García-Alberca

  • Unitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain

    Gerard Piñol-Ripoll, Alfonso Arias Pastor & Raquel Huerto Vilas

  • Institut de Recerca Biomedica de Lleida (IRBLLeida), Lleida, Spain

    Gerard Piñol-Ripoll, Alfonso Arias Pastor & Raquel Huerto Vilas

  • Alzheimer Research Center & Memory Clinic, Andalusian Institute for Neuroscience, Málaga, Spain

    Jose María García-Alberca, Jose Maria García-Alberca & Silvia Mendoza

  • Neurology Service, Marqués de Valdecilla University Hospital (University of Cantabria and IDIVAL), Santander, Spain

    Eloy Rodriguez-Rodriguez, Carmen Lage & Pascual Sánchez-Juan

  • Institute of Clinical Medicine – Neurology, University of Eastern Finland, Kuopio, Finland

    Hilkka Soininen

  • Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland

    Sami Heikkinen & Mikko Hiltunen

  • Faculty of Medicine, University of Lisbon, Lisbon, Portugal

    Alexandre de Mendonça & Catarina B. Ferreira

  • Clinic of Neurology, UH “Alexandrovska”, Medical University – Sofia, Sofia, Bulgaria

    Shima Mehrabian & Latchezar Traykov

  • Department of Neurology, Medical University – Sofia, Sofia, Bulgaria

    Latchezar Traykov

  • Memory Clinic, Department of Neurology, Charles University, Second Faculty of Medicine and Motol University Hospital, Praha, Czech Republic

    Jakub Hort

  • Memory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Praha, Czech Republic

    Martin Vyhnalek & Ondrej Lerch

  • International Clinical Research Center, St. Anne’s University Hospital Brno, Brno, Czech Republic

    Martin Vyhnalek & Ondrej Lerch

  • Department of Clinical Biochemistry, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark

    Nicolai Sandau, Jesper Qvist Thomassen, Anne Tybjærg-Hansen & Ruth Frikke-Schmidt

  • Department of Clinical Genetics, VU University Medical Centre, Amsterdam, The Netherlands

    Henne Holstege

  • Department of Neurology, ErasmusMC, Rotterdam, Netherlands

    John van Swieten, Merel Mol & Jeroen van Rooij

  • Maastricht University, Department of Psychiatry & Neuropsychologie, Alzheimer Center Limburg, Maastricht, the Netherlands

    Inez Ramakers & Frans Verhey

  • Unit for Hereditary Dementias, Theme Aging, Karolinska University Hospital-Solna, 171 64, Stockholm, Sweden

    Caroline Graff

  • Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden

    Goran Papenberg, Giulia Grande & Erika J. Laukka

  • Dept.of Public Health and Carins Sciences / Geriatrics, Uppsala University, Uppsala, Sweden

    Vilmantas Giedraitis, Lena Kilander & Malin Löwemark

  • Université Paris-Saclay, CEA, Centre National de Recherche en Génomique Humaine, 91057, Evry, France

    Anne Boland, Jean-François Deleuze, Céline Besse, Delphine Daian, Bertrand Fin & Robert Olaso

  • Univ Rouen Normandie, Normandie Univ, Inserm U1245 and CHU Rouen, Department of Genetics and CNRMAJ, F-, 76000, Rouen, France

    Gael Nicolas & Olivier Quenez

  • Inserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, CIC 1401-EC, Univ Bordeaux, Bordeaux, France

    Carole Dufouil & Geneviève Chene

  • CHU de Bordeaux, Pole santé publique, Bordeaux, France

    Carole Dufouil & Geneviève Chene

  • Univ Lille Inserm 1171, CHU Clinical and Research Memory Research Centre (CMRR) of Distalz Lille France, Lille, France

    Florence Pasquier

  • Université de Paris, EA 4468, APHP, Hôpital Broca, Paris, France

    Olivier Hanon, Henri Bailly, Emmanuelle Duron & Jean-Sebastian Vidal

  • University Bordeaux, Inserm, Bordeaux Population Health Research Center, Bordeaux, France

    Stéphanie Debette & Jean-François Dartigues

  • Department of Neurology, Bordeaux University Hospital, Bordeaux, France

    Stéphanie Debette

  • Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland

    Edna Grünblatt

  • Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland

    Edna Grünblatt

  • Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland

    Edna Grünblatt

  • CHUV, Old Age Psychiatry, Department of Psychiatry, Lausanne, Switzerland

    Julius Popp

  • Old Age Psychiatry, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland

    Julius Popp

  • Department of Geriatric Psychiatry, University Hospital of Psychiatry Zürich, Zürich, Switzerland

    Julius Popp

  • Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy

    Roberta Ghidoni, Barbara Borroni, Sonia Bellini & Silvia Fostinelli

  • Neurodegenerative Diseases Unit, Fondazione IRCCS Ca’ Granda, Ospedale Policlinico, Milan, IT, Italy

    Daniela Galimberti

  • Dept. of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, IT, Italy

    Daniela Galimberti

  • Department of Clinical Sciences and Community Health, University of Milan, 20122, Milan, Italy

    Beatrice Arosio

  • Geriatric Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, 20122, Milan, Italy

    Beatrice Arosio

  • Institute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, Perugia, Italy

    Patrizia Mecocci, Roberta Cecchetti & Michela Scamosci

  • Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden

    Patrizia Mecocci

  • Interdisciplinary Department of Medicine, Geriatric Medicine and Memory Unit, University of Bari “A. Moro”, Bari, Italy

    Vincenzo Solfrizzi

  • Centre for Memory Disturbances, Lab of Clinical Neurochemistry, Section of Neurology, University of Perugia, Perugia, Italy

    Lucilla Parnetti & Lucia Farotti

  • Department of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, Cagliari, Italy

    Alessio Squassina

  • Neurology Unit, “San Gerardo” hospital, Monza and University of Milano-Bicocca, Milan, Italy

    Lucio Tremolizzo

  • Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy

    Barbara Borroni

  • Cognitive and Behavioural Neurology, Department of Continuity of Care and Frailty, ASST Spedali Civili Brescia, Brescia, Italy

    Barbara Borroni

  • Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Medical Faculty, Bonn, Germany

    Michael Wagner & Alfredo Ramirez

  • Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence, Florence, Italy

    Benedetta Nacmias, Valentina Bessi & Sandro Sorbi

  • IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy

    Benedetta Nacmias & Sandro Sorbi

  • Department of Medicine and Surgery, Unit of Neurology, University-Hospital of Parma, Parma, Italy

    Marco Spallazzi

  • Department of Hematology and Stem Cell Transplant, Vito Fazzi Hospital, Lecce, Italy

    Davide Seripa

  • Department of Neuroscience “Rita Levi Montalcini”, University of Torino, Torino, Italy

    Innocenzo Rainero & Silvia Boschi

  • Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy

    Antonio Daniele, Guido Maria Giuffrè & Maria Gabriella Vita

  • Neurology Unit, IRCCS Fondazione Policlinico Universitario A. Gemelli, Rome, Italy

    Antonio Daniele

  • Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy

    Fabrizio Piras

  • Institute of Neurology, Catholic University of the Sacred Heart, Rome, Italy

    Carlo Masullo

  • Unit of Neurology V – Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy

    Giacomina Rossi

  • Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

    Frank Jessen

  • Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany

    Frank Jessen

  • Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK

    Patrick Kehoe

  • Laboratory of Genetics, Immunology and Human Pathology, Faculty of Science of Tunis, University of Tunis El Manar, 2092, Tunis, Tunisia

    Tsolaki Magda

  • Alzheimer’s Centre Reina Sofia-CIEN Foundation-ISCIII, 28031, Madrid, Spain

    Pascual Sánchez-Juan

  • Dept. of Public Health and Caring Sciences / Geriatrics, Uppsala University, Uppsala, Sweden

    Martin Ingelsson

  • Krembil Brain Institute, University Health Network, Toronto, Ontario, Canada

    Martin Ingelsson

  • Tanz Centre for Research in Neurodegenerative Diseases, Departments of Medicine and Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada

    Martin Ingelsson

  • NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway

    Ole A. Andreassen

  • Institute of Clinical Medicine, University of Oslo, Oslo, Norway

    Ole A. Andreassen, Tormod Fladby & Geir Selbæk

  • Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain

    Agustín Ruiz, Victoria Fernández, Amanda Cano, Carla Abdelnour, Emilio Alarcón-Martín, Montserrat Alegret, Mercè Boada, Josep Blázquez, Pablo García-González, Isabel Hernández, Marta Marquié, Laura Montrreal, Adelina Orellana, Maria Capdevila, Marta Martinez-Lucas, Raquel Puerta, Claudia Olivé, Maitée Rosende-Roca, Fernando García-Gutierrez, Oscar Sotolongo-Grau, Andrea Miguel, Lluís Tárraga & Sergi Valero

  • Biggs Institute for Alzheimer’s and Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, Texas, USA

    Agustín Ruiz

  • Department of Psychiatry & Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases, San Antonio, TX, USA

    Alfredo Ramirez

  • Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Disease (CECAD), University of Cologne, Cologne, Germany

    Alfredo Ramirez

  • Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

    Børge G. Nordestgaard, Anne Tybjærg-Hansen & Ruth Frikke-Schmidt

  • Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands

    Gennady Roshchupkin

  • Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands

    Gennady Roshchupkin

  • Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands

    Shahzad Ahmad, Mohsen Ghanbari & Cornelia van Duijn

  • Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany

    Victor Andrade

  • Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany

    Victor Andrade & Wolfgang Maier

  • Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, 50937, Cologne, Germany

    Maria-Carolina Dalmasso & Luca Kleineidam

  • Department of Cognitive Disorders and Old Age Psychiatry, University of Bonn, Bonn, Germany

    Luca Kleineidam

  • German Center for Neurodegenerative Diseases (DZNE Bonn), Bonn, Germany

    Luca Kleineidam, Klaus Fließbach & Wolfgang Maier

  • LACDR, Leiden, The Netherlands

    Shahzad Ahmad

  • Centre of Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway

    Dag Aarsland

  • Institute of Psychiatry, Psychology & Neuroscience, PO 70, 16 De Crespigny Park, London, SE58AF, UK

    Dag Aarsland

  • Department of Surgery, Biochemistry and Molecular Biology, School of Medicine, University of Málaga, Málaga, Spain

    Emilio Alarcón-Martín

  • Fundació Docència i Recerca MútuaTerrassa and Movement Disorders Unit, Department of Neurology, University Hospital MútuaTerrassa, Terrassa, 08221, Barcelona, Spain

    Ignacio Alvarez & Mónica Diez-Fairen

  • Centre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, Australia

    Nicola J. Armstrong, Henry Brodaty, Anbupalam Thalamuthu, Perminder Sachdev & Karen Mather

  • Alzheimer Hellas, Thessaloniki, Makedonia, Greece

    Tsolaki Anthoula

  • School of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy

    Ildebrando Appollonio & Elisa Conti

  • Neurology Unit, “San Gerardo” hospital, Monza, Italy

    Ildebrando Appollonio

  • Fondazione IRCCS Ca’ Granda, Ospedale Policlinico, Milan, Italy

    Marina Arcaro & Elio Scarpini

  • Department of Laboratory Diagnostics, III Laboratory of Analysis, Brescia Hospital, Brescia, Italy

    Silvana Archetti

  • NORMENT Centre, University of Oslo, Oslo, Norway

    Lavinia Athanasiu, Srdjan Djurovic & Alexey A. Shadrin

  • Laboratory of Neuropsychiatry, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy

    Nerisa Banaj

  • Servei de Neurologia, Hospital Universitari i Politècnic La Fe, Valencia, Spain

    Miquel Baquero

  • CIEN Foundation/Queen Sofia Foundation Alzheimer Center, Madrid, Spain

    Ana Belén Pastor, Miguel Calero, Miguel Medina & Alberto Rábano

  • Univ. Montpellier, Inserm U1061, Neuropsychiatry: epidemiological and clinical research, PSNREC, Montpellier, France

    Claudine Berr

  • Azienda Ospedaliero-Universitaria Careggi, Florence, Italy

    Valentina Bessi

  • MAC-Memory Clinic and Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy

    Giuliano Binetti & Silvia Fostinelli

  • Geriatrics Unit Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy

    Alessandra Bizarro & Alessandra Lauria

  • Experimental Neuro-psychobiology Laboratory,Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy

    Paola Bossù

  • Department of Neurology and Clinical Neurophysiology, University Hospital of Trondheim, Trondheim, Norway

    Geir Bråthen & Sigrid B. Sando

  • Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway

    Geir Bråthen, Ingvild Saltvedt & Sigrid B. Sando

  • MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK

    Catherine Bresner, Ganna Leonenko, Janet Harwood, Lauren Luckcuck & Rachel Marshall

  • Dementia Centre for Research Collaboration, School of Psychiatry, University of New South Wales, Sydney, Australia

    Henry Brodaty

  • Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham, UK

    Keeley J. Brookes

  • Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany

    Katharina Bûrger & Michael Ewers

  • German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany

    Katharina Bûrger & Michael Ewers

  • Faculty of Medical & Health Sciences, University of Auckland, Auckland, New Zealand

    Vanessa Burholt

  • Wales Centre for Ageing & Dementia Research, Swansea University, Wales, New Zealand

    Vanessa Burholt

  • UFIEC, Instituto de Salud Carlos III, Madrid, Spain

    Miguel Calero

  • Grupo de Medicina Xenómica, Centro Nacional de Genotipado (CEGEN-PRB3-ISCIII). Universidade de Santiago de Compostela, Santiago de Compostela, Spain

    Ángel Carracedo & Inés Quintela

  • Fundación Pública Galega de Medicina Xenómica- CIBERER-IDIS, University of Santiago de Compostela, Santiago de Compostela, Spain

    Ángel Carracedo

  • Univ Rouen Normandie, Normandie Univ, Inserm U1245 and CHU Rouen, Department of Biostatistics and CNRMAJ, F-76000, Rouen, France

    Camille Charbonnier

  • Unit of Clinical Pharmacology, University Hospital of Cagliari, Cagliari, Italy

    Caterina Chillotti

  • Geriatic Unit, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy

    Simona Ciccone, Paolo Dionigi Rossi & Evelyn Ferri

  • Radboudumc Alzheimer Center, Department of Geriatrics, Radboud University Medical Center, Nijmegen, the Netherlands

    Jurgen A. H. R. Claassen

  • Institute for Regenerative Medicine, University of Zürich, Schlieren, Switzerland

    Christopher Clark

  • University of Bari, “A. Moro”, Bari, Italy

    Carlo Custodero

  • School of Medicine, University of Thessaly, Larissa, Greece

    Efthimios Dardiotis

  • Department of Neurology, University Medical Center Groningen, Groningen, the Netherlands

    Peter Paul de Deyn

  • Department of Neurology/CIEN Foundation/Queen Sofia Foundation Alzheimer Center, Madrid, Spain

    Teodoro del Ser

  • Technical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Psychiatry and Psychotherapy, Munich, Germany

    Janine Diehl-Schmid & Oliver Goldhardt

  • Center for Neurosciences, Vrije Universiteit Brussel (VUB), Brussels, Belgium

    Sebastiaan Engelborghs

  • Reference Center for Biological Markers of Dementia (BIODEM), Institute Born-Bunge, University of Antwerp, Antwerp, Belgium

    Sebastiaan Engelborghs

  • Institute Born-Bunge, University of Antwerp, Antwerp, Belgium

    Sebastiaan Engelborghs

  • Department of Neurology, UZ Brussel, Brussels, Belgium

    Sebastiaan Engelborghs

  • Fondazione IRCCS, Istituto Neurologico Carlo Besta, Milan, Italy

    Tagliavini Fabrizio & Giaccone Giorgio

  • Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Herlev, Denmark

    Sune Fallgaard Nielsen

  • University of Milan, Milan, Italy

    Chiara Fenoglio & Elio Scarpini

  • Department of Psychiatry, Social Medicine Center East- Donauspital, Vienna, Austria

    Peter Fischer

  • Department of Neurodegeneration and Geriatric Psychiatry, University of Bonn, 53127, Bonn, Germany

    Klaus Fließbach & Michael Wagner

  • Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana, USA

    Tatiana M. Foroud

  • Dementia Research Centre, UCL Queen Square Institute of Neurology, London, United Kingdom

    Nick C. Fox & Jonathan M. Schott

  • Unidad de Demencias, Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain

    Emlio Franco-Macías & María Bernal Sánchez-Arjona

  • Hospital Universitario la Paz, Madrid, Spain

    Ana Frank-García & Angel Martín Montes

  • Department of geriatric Psychiatry, Central Institute for Mental Health, Mannheim, University of Heidelberg, Mannheim, Germany

    Lutz Froelich

  • Hospital Universitario Ramon y Cajal, IRYCIS, Madrid, Spain

    Sebastian Garcia-Madrona & Guillermo Garcia-Ribas

  • Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria

    Ina Giegling & Annette M. Hartmann

  • CAEBI, Centro Andaluz de Estudios Bioinformáticos, Sevilla, Spain

    Antonio González-Pérez & María Eugenia Sáez

  • Institute of Public Health, University of Cambridge, Cambridge, UK

    Emma Green

  • Human Genetics, School of Life Sciences, Life Sciences Building, University Park, University of Nottingham, Nottingham, UK

    Tamar Guetta-Baranes

  • A.I Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland

    Annakaisa Haapasalo

  • Department of Neurology, Medical School, University of Cyprus, Nicosia, Cyprus

    Georgios Hadjigeorgiou

  • Sorbonne University, GRC n° 21, Alzheimer Precision Medicine Initiative (APMI), AP-HP, Pitié-Salpêtrière Hospital, Boulevard de l’hôpital, F-, 75013, Paris, France

    Harald Hampel

  • Eisai Inc., Neurology Business Group, 100 Tice Blvd, Woodcliff Lake, NJ, 07677, USA

    Harald Hampel

  • Reta Lila Weston Research Laboratories, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK

    John Hardy

  • Insitute of Clinical Medicine – Neurology, University of Eastern, Kuopio, Finland

    Seppo Helisalmi, Anne Koivisto, Jenni Lehtisalo & Alina Solomon

  • Institute of Clinical Medicine – Internal Medicine, University of Eastern Finland, Kuopio, Finland

    Seppo Helisalmi

  • Department of Neurodegeneration and Geriatric Psychiatry, University of Bonn, Bonn, Germany

    Michael T. Heneka

  • German Center for Neurodegenerative Diseases (DZNE, Bonn), Bonn, Germany

    Michael T. Heneka, Matthias Schmid, Annika Spottke & Michael Wagner

  • Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital, Wuerzburg, Germany

    Martin J. Herrmann & Thomas Polak

  • Clinical and Experimental Science, Faculty of Medicine, University of Southampton, Southampton, UK

    Clive Holmes

  • Section Genomics of Neurdegenerative Diseases and Aging, Department of Human Genetics Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands

    Marc Hulsman & Niccolo Tesí

  • Department of Neurology, UMC Utrecht Brain Center, Utrecht, the Netherlands

    Geert Jan Biessels

  • Karolinska Institutet, Center for Alzheimer Research, Department NVS, Division of Neurogeriatrics, Stockholm, Sweden

    Charlotte Johansson, Anne Kinhult Ståhlbom & Abbe Ullgren

  • Unit for Hereditary dementias, Karolinska University Hospital-Solna, Stockholm, Sweden

    Charlotte Johansson & Anne Kinhult Ståhlbom

  • Division of Clinical Geriatrics, Center for Alzheimer Research, Care Sciences and Society (NVS), Karolinska Institutet, Stockholm, Sweden

    Miia Kivipelto, Francesca Mangialasche & Alina Solomon

  • Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland

    Miia Kivipelto

  • Neuroepidemiology and Ageing Research Unit, School of Public Health, Imperial College London, London, United Kingdom

    Miia Kivipelto

  • Stockholms Sjukhem, Research & Development Unit, Stockholm, Sweden

    Miia Kivipelto

  • Department of Neurology, Kuopio University Hospital, Kuopio, Finland

    Anne Koivisto

  • Department of Neurosciences, University of Helsinki and Department of Geriatrics, Helsinki University Hospital, Helsinki, Finland

    Anne Koivisto

  • Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany

    Johannes Kornhuber

  • Laboratory of Cognitive Neuroscience, School of Psychology, Aristotle University of Thessaloniki, Thessaloniki, Greece

    Mary H. Kosmidis

  • Stockholm Gerontology Research Center, Stockholm, Sweden

    Erika J. Laukka

  • Public Health Promotion Unit, Finnish Institute for Health and Welfare, Helsinki, Finland

    Jenni Lehtisalo & Tiia Ngandu

  • Department of Neurology. Hospital Universitario Donostia. OSAKIDETZA-Servicio Vasco de Salud, San Sebastian, Spain

    Adolfo Lopez de Munain

  • Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS16 1LE, UK

    Seth Love & Olivia Skrobot

  • School of Health Sciences, Bangor University, Bangor, UK

    Catherine A. MacLeod, Gill Windle & Bob Woods

  • Unit of Neurology, University of Parma and AOU, Parma, Italy

    Spallazzi Marco

  • Servicio de Neurología HOspital Universitario Central de Asturias- Oviedo and Instituto de Investigación Biosanitaria del Principado de Asturias, Oviedo, Spain

    Carmen Martínez Rodríguez & Manuel Menéndez-González

  • MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, W1W 7FF, UK

    Simon Mead

  • Human Genetics, School of Life Sciences, University of Nottingham, NG7 2UH, Nottingham, UK

    Kevin Morgan

  • Department of Clinical Biochemistry, Copenhagen University Hospital – Herlev and Gentofte, Herlev, Denmark

    Børge G. Nordestgaard

  • Department of Neuroscience, Catholic University of Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

    Michela Orsini

  • Centre for Neurodegenerative Disorders, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy

    Alessandro Padovani

  • DIMEC, University of Parma, Parma, Italy

    Caffarra Paolo

  • Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41-UMS 2014-PLBS, bilille, Lille, France

    Pierre Pericard

  • Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy

    Claudia Pisanu

  • Department of Neuropsychiatry and Laboratory of Molecular Psychiatry, Charité, Charitéplatz 1, 10117, Berlin, Germany

    Josef Priller

  • BT-CIEN, Madrid, Spain

    Alberto Rábano

  • Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands

    Marcel J. T. Reinders

  • Center of Mental Health, Clinic and Policlinic of Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg, Wuerzburg, Germany

    Peter Riederer

  • Department of Research and Innovation, Helse Fonna, Haugesund Hospital, Haugesund, Norway

    Arvid Rongve

  • The University of Bergen, Institute of Clinical Medicine (K1), Bergen, Norway

    Arvid Rongve

  • Departamento de Especialidades Quirúrgicas, Bioquímicas e Inmunología, School of Medicine, University of Málaga, Málaga, Spain

    Jose Luis Royo

  • Department of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino, Torino, Italy

    Elisa Rubino

  • Athens Association of Alzheimer’s disease and Related Disorders, Athens, Greece

    Paraskevi Sakka

  • Department of Geriatrics, St. Olav’s Hospital, Trondheim University Hospital, Trondheim, Norway

    Ingvild Saltvedt

  • Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Las Palmas, Spain

    Florentino Sanchez-Garcia

  • Neurology department-Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain

    Raquel Sánchez-Valle

  • Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, 20246, Hamburg, Germany

    Martin Scherer

  • Institute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany

    Matthias Schmid & Leonie Weinhold

  • Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway

    Geir Selbæk & Ingun Ulstein

  • Department of Neurology, University of Bonn, Bonn, Germany

    Annika Spottke

  • Department of Psychiatry, Namsos Hospital, Namsos, Norway

    Eystein Stordal

  • Department of Internal medicine and Biostatistics, ErasmusMC, Rotterdam, The Netherlands

    Andre Uitterlinden

  • Laboratory of Neurogenetics, Institute Born – Bunge, Antwerp, Belgium

    Christine Van Broeckhoven & Jasper Van Dongen

  • Department of Biomedical Sciences, University of Antwerp, Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Antwerp, Belgium

    Christine Van Broeckhoven & Jasper Van Dongen

  • Neurodegenerative Brain Diseases Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium

    Christine Van Broeckhoven

  • Department of Internal Medicine, ErasmusMC, Rotterdam, The Netherlands

    Jeroen van Rooij

  • Laboratory for Cognitive Neurology, Department of Neurosciences, University of Leuven, Leuven, Belgium

    Rik Vandenberghe

  • Neurology Department, University Hospitals Leuven, Leuven, Belgium

    Rik Vandenberghe

  • Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, MA, USA

    Jonathan Vogelgsang

  • Univ Rouen Normandie, Normandie Univ, Inserm U1245 and CHU Rouen, Department of Neurology and CNRMAJ, F-76000, Rouen, France

    David Wallon

  • Department of Nutrition and Diatetics, Harokopio University, Athens, Greece

    Mary Yannakoulia

  • Neurosciences Area. Instituto Biodonostia, San Sebastian, Spain

    Miren Zulaica

  • Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia

    Perminder Sachdev

  • Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands

    Mohammad Arfan Ikram

    • M.B.S., F.M. (Federico Melograna) and B.U. contributed equally to the study conception and design, analysis and interpretation of data, creation of code for analysis and primary drafting and revision of the manuscript. C.B., B.G.B., D.D., A.J.N., P.H., B.M.T., M.H. (Marc Hulsman), I.D.R., R.C.M., A.R. (Agustín Ruiz), R.F.S., N.A., G.R. (Gennady Roshchupkin) and J.C. contributed to the study design, interpretation of data or substantial revisions. K.V.S., C.V.D. and V.E.P. contributed equally to the study conception, interpretation of data, manuscript drafting and substantial revisions. All remaining authors—S.V.D.L., A.C., F.K., O.P., A.S. (Anja Schneider), M.D., D.R., N.S. (Norbert Scherbaum), J.D., S.R.H., L.H., L.M.P., E.D., T.G., J.W. (Jens Wiltfang), S.H.H., S.M. (Susanne Moebus), T.T., N.S. (Nikolaos Scarmeas), O.D.I., F.M. (Fermin Moreno), J.P.T., M.J.B., P.P., R.S.V., V.A., M.B., P.G.G., R.P., P.M. (Pablo Mir), L.M.R., G.P.R., J.M.G.A., E.R.R., H.S., S.H., A.D.M., S.M. (Shima Mehrabian), L.T. (Latchezar Traykov), J.H., M.V., N.S. (Nicolai Sandau), J.Q.T., Y.A.P., H.H., J.V.S., I.R. (Inez Ramakers), F.V., P.S., C.G., G.P., V.G., J.W. (Julie Williams), P.A., A.B., J.F.D., G.N., C.D., F.P. (Florence Pasquier), O.H., S.D., E.G., J.P., R.G., D.G., B.A., P.M. (Patrizia Mecocci), V.S., L.P., A.S. (Alessio Squassina), L.T. (Lucio Tremolizzo), B.B., M.W., B.N., M.S., D.S., I.R. (Innocenzo Rainero), A.D., F.P. (Fabrizio Piras), C.M., G.R., F.J., P.K., T.M., P.S.J., K.S., M.I., M.H. (Mikko Hiltunen), R.S., W.V.D.F., O.A.A., A.R. (Alfredo Ramirez), and those in the EADB umbrella group (see Supplementary)—contributed to data acquisition and/or minor revisions.