Through three games, Arizona has been one of the best bets in college football. The Wildcats are 3-0 against the spread (ATS) and are covering by an average 13 points.
Will that trend continue this week when the Wildcats open Big 12 play on the road?
Arizona has opened as a 6.5-point underdog at Iowa State, according to FanDuel Sportsbook. Arizona and No. 12 Iowa State kick off at 4 p.m. PST Saturday on ESPN.
Arizona is coming off a 23-17 home victory over Kansas State in a game it entered as a slight underdog. Both Arizona and Iowa State had bye weeks this weekend.
Arizona is 6-3-1 ATS in its last 10 games coming off a bye week, dating back to to 2014. Last year Arizona covered only two games all season and both were after byes: The UA beat Utah 23-10 as a 7.5-point underdog and defeated Houston 27-3 as a 1.5-point favorite.
The Wildcats went 1-3 ATS last season as road underdogs of at least six points, with the one cover coming against Utah.
Arizona faces an Iowa State program that is 2-1-1 ATS in 2025. The Cyclones were three-touchdown favorites last week at Arkansas State and failed to cover, winning 24-16. Iowa State is 5-5 in its last 10 games coming off a bye.
Arizona and Iowa State are playing for the first time since 1968. Arizona defeated the Cyclones in Ames 21-12 that year. Arizona is 4-1-1 all time in the series.