As weight-loss drugs have exploded in popularity this past year, part of the craze has been members of the public wondering which celebrities are on Ozempic.
The drug is approved to treat Type 2 diabetes and has weight loss as a prominent side effect, so it’s often prescribed off-label for this reason. The active ingredient in Ozempic, semaglutide, is also approved to treat obesity under the name Wegovy. (Novo Nordisk, the maker of Ozempic, previously told TODAY.com in a statement that it does not support off-label use of its medications.)
Examples of other similar drugs include Mounjaro, approved for diabetes, and Zepbound, approved for obesity, both made by Eli Lilly.
It’s hard to escape the numerous Ozempic before-and-after photos on social media of people who have seen drastic results while using the medication. And whenever a celebrity has appeared looking slimmer as of late, the Ozempic accusations always follow.
There are a few celebrities who’ve spoken openly about taking weight-loss medications. Here’s what they’ve said.
(If you are interested in trying a weight-loss medication, talk to your doctor first.)
Chrissy Teigen
Nathan Congleton / TODAY
In Sept. 2025, Christy Teigen revealed she turned to Ozempic following her 2020 miscarriage, during an episode of her podcast Self-Conscious.
She said that, at the time, it was her response to her “deep depression of seeing this pregnant belly with no baby in it.”
“My body was completely stuck,” she said. “I really let myself indulge when I was pregnant. So, when I had lost that baby at 20 weeks, I had probably gained an extra 40 pounds that I wasn’t comfortable with.”
Teigen said she also struggled with the reduction in hunger cues often associated with medications used for weight loss. “It was frustrating for me because I know that logically you need food to have energy,” she added.
Serena Williams
Courtesy Ro
After the birth of her second child, Serena Williams turned to a GLP-1 medication to help with weight loss, she revealed exclusively to TODAY.
The tennis star said she’s proof that you can do everything right and still struggle to lose weight. Combined with her professional training, Williams would “walk for hours,” she switched to a vegetarian diet, then a vegan one and, still, she struggled to shed the pounds.
“A misconception is that (a GLP-1 is) a shortcut,” she told TODAY.com. “As an athlete and as someone that has done everything, I just couldn’t get my weight to where I needed to be at a healthy place — and believe me, I don’t take shortcuts.”
Since using a GLP-1, Williams says her blood sugar levels have improved and her joints feel lighter.
Meghan Trainor
Meghan Trainor at the Billboard Women in Music 2025 held at the YouTube Theater on March 29, 2025 in Los Angeles, California.Christopher Polk / Billboard via Getty Images
Following a big win at the 2025 Billboard Women in Music awards, Meghan Trainor noticed most of the comments were about her body rather than her accomplishment.
“…It’s a little disheartening that so many of the questions (and comments) were focused on my body instead of my music, my passion, or the decade of hard work that got me here. This is what it’s like to be a woman in the music industry,” she wrote on Instagram.
She pointed out that she’s worked with a dietitian and a trainer to be the best version of herself for her children and that process also included turning to the weight loss drug Mounjaro.
“I’ve worked with a dietician, made huge lifestyle changes, started exercising with a trainer, and yes, I used science and support (shoutout to Mounjaro!) to help me after my 2nd pregnancy. And I’m so glad I did because I feel great,” she said.
Oprah Winfrey 
Oprah WinfreyLeon Bennett / Getty Images
During an interview with People in December 2023, Winfrey revealed that she takes a weight-loss drug, but didn’t specify which one.
“I now use it as I feel I need it, as a tool to manage not yo-yoing,” she said.
The TV personality, who has spoken at length about her weight struggles throughout her career, told People the drug helps her maintain a healthy weight.
“The fact that there’s a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for. I’m absolutely done with the shaming from other people and particularly myself,” she said.
Once upon a time, Winfrey considered weight-loss drugs an “easy way out,” but she’s changed her tune since then.
“I realized I’d been blaming myself all these years for being overweight, and I have a predisposition that no amount of willpower is going to control,” she said.
Kelly Clarkson
Kelly Clarkson on May 13, 2024, in NYC.Ralph Bavaro/NBCUniversal / Getty Images
Kelly Clarkson revealed during an episode of her talk show when speaking with Whoopi Goldberg that she is taking a drug to help her lose weight, though she didn’t specify which one.
“Everyone thinks it’s Ozempic — it’s not. It’s something else,” Clarkson said. “But it’s something that aids in helping break down the sugar. Obviously my body doesn’t do it right.”
Clarkson added that taking a weight-loss medication has been “really good” for her, even though she was hesitant to try it at first due to past health issues.
“My doctor chased me for like two years, and I was like, ‘No I’m afraid of it, I already have thyroid problems,’” she said.
She ultimately decided to try it “because my blood work got so bad,” she said.
“My heaviest, I was like 203, and I’m 5 foot 3 and a half,” Clarkson continued. “It’s funny because people assume, ‘Oh she must’ve been miserable, depressed, whatever,’ and I was like, ‘No I was not.’”
Kathy Bates
Kathy Bates in July 2024. Willy Sanjuan / AP
Kathy Bates recently shared that she lost 100 pounds over the past seven years thanks to lifestyle changes as well as Ozempic.
“There’s been a lot of talk that I just was able to do this because of Ozempic,” Bates told People. “But I have to impress upon people out there that this was hard work for me, especially during the pandemic. It’s very hard to say you’ve had enough.”
She also opened up about her weight loss journey on during an October 2024 appearance on “The Drew Barrymore Show.”
“I’ve recently gone on Ozempic and everybody said, ‘Oh, she did it with Ozempic’ but that’s not true. I started doing that about a year ago for my diabetes and that’s helped me lose the last 15 pounds or so,” she told Barrymore. “But even with the Ozempic, I still have to pay attention (to my eating.”
Harvey Fierstein
Harvey Fierstein on June 16, 2024.Mary Kouw/CBS / Getty Images
The Broadway legend shared that he lost 120 pounds using Zepbound. He tried it after reaching 310 pounds during the COVID-19 pandemic.
“What’s different is what the drug actually does for you, which is: I don’t feel like I’m dieting,” Fierstein told Page Six. “I feel like a normal person. I can go and have dinner with friends and not have to eat every piece of bread on the table, and then not go have ice cream when I’ve done with dinner.”
“People don’t understand that being fat is not a choice,” he added. “It’s something that your body is out of whack and this puts your body in whack.”
Fierstein shared that after going off the medication, he regained about 15 pounds but has stayed at around 200 pounds.
Jim Gaffigan
Jim Gaffigan on Dec. 03, 2024 in NYC.Dia Dipasupil / Getty Images
Comedian Jim Gaffigan told People in November 2024 that he lost 50 pounds using Mounjaro. He made the decision to try the medication after reaching 270 pounds.
“I had very low expectations because I did know someone that had tried it, and they were like, ‘Oh no, I was just nauseous for a week,’” he said. “And then I thought my true joy of eating would overpower anything.”
But it turned out to be an effective approach for him. “I feel good,” he told People. “I’m just grateful because it’s such a better life.”
He added that he’s sharing his experience to destigmatize weight-loss drugs.
“I almost thought it was kind of odd that people were resistant to talking about it. I don’t think there’s anything wrong with it. There’s people walking around that obviously do not have blonde hair — yet they do. I don’t think that’s weird, either. It’s just whatever gets you through,” Gaffigan said.
James Corden
James Corden on Dec. 2, 2024 in London, England.Dave Benett / Getty Images
James Corden said he tried Ozempic but it was not that effective for him in September on his podcast.
“I tried Ozempic, and it won’t be surprising to you when you look at me now, that it didn’t really work,” Corden said. “I tried it for a bit and then what I realized was I was like, ‘Oh no, nothing about my eating has anything to do with being hungry.’ All this does is make you feel not hungry.”
Kandi Burruss
Kandi Burruss on Oct. 20, 2024 in NYC.John Nacion / FilmMagic
The former Xscape member revealed that she tried a weight-loss drug on the Virtual Reali-Tea podcast in June.
“Last year, I tried it. I saw so many people who were trying it and losing weight. So I was like, ‘OK, I’m going to try this.’ And I didn’t lose any weight,” she said.
“My doctor was like, ‘I don’t know what the problem is, I’m not seeing this in other people.’ … It didn’t curb my appetite. I know some people are like, ‘Oh, I can’t eat.’ Not me. I was eating appetizers, a regular meal and dessert. It didn’t stop anything for me.”
She had mental health struggles when the drug didn’t work for her, she said: “It makes you depressed. Realistically, it makes you feel like, ‘What is wrong with me? Why is it not working for me?'”
Amy Schumer 
Amy Schumer Nathan Congleton / TODAY
While chatting with Andy Cohen in June 2023, Schumer confirmed that she did try Ozempic “like a year ago” but quickly stopped due to the side effects.
“I was one of the people that felt like sick, I couldn’t like play with my son,” she said during an episode of “Watch What Happens Live with Andy Cohen.”
Despite the results she began to see, Schumer said it wasn’t worth it to continue taking the drug.
“You’re like, ‘OK, this isn’t livable for me,’ but I immediately invested because I’m like, ‘Everyone and their mom is going to try it,’” she said.
The comedian also encouraged other celebrities to be more honest if they are using Ozempic or similar medications.
“Everybody (is) lying, everyone’s like, ‘Oh, smaller portions,’ like shut the f— up, you’re on Ozempic or one of those things,” she said. “Just be real with the people.”
In order to “keep it 100” with her fans and social media followers, Schumer revealed she was taking Mounjaro, a prescription drug that’s approved to treat Type 2 diabetes and also commonly prescribed for weight loss. In the video, posted on Instagram March 2025, she revealed that she’d had a “really good experience” on Mounjaro. Before that, she’d also tried Wegovy which she said she couldn’t “handle.”
Whoopi Goldberg
Whoopi Goldberg on The Kelly Clarkson Show. Weiss Eubanks / NBC
Whoopi Goldberg told Kelly Clarkson that she had lost the weight of “almost two people” since starting Mounjaro, a medication approved to treat Type 2 diabetes.
“I’m doing that wonderful shot that works for folks who need some help and it’s been really good for me,” Goldberg told Clarkson after she commented on how youthful Goldberg looks. “It’s all the weight I’ve lost.”
The EGOT winner previously revealed she was taking Mounjaro on “The View” in March.
“My weight has come and gone, and up and down, but it’s never been an issue for me because I don’t listen to what other people say about me so it has never been a problem,” she said. “But I think it’s very hard for people to just know what a normal weight would be. … Everyone has something to say but no one said, ‘How you doing?’ Because it involves so many other things.”
Tracy Morgan 
Tracy Morgan Amy Sussman / Getty Images
While appearing on TODAY with Hoda & Jenna in August 2023, Morgan approached the topic of his Ozempic use in a comedic way.
“You’ve been working on your body and on your health,” Hoda Kotb said.
Morga cheekily replied: “No, that’s Ozempic. That’s how this weight got lost.”
It initially seemed like a joke, but he later confirmed it was true. “I went and got a prescription and I got Ozempic,” he said. “And I ain’t letting it go!”
In a March 2024 appearance on “The Tonight Show Starring Jimmy Fallon,” Morgan said he’s gained weight on Ozempic.
“I’ve learned to out-eat Ozempic. I out-ate Ozempic. I’ve gained 40 pounds,” Morgan quipped with a joking tone.
It’s not clear if Morgan is still taking the medication, but gaining weight after stopping a weight-loss drug is common, research shows.
Sharon Osbourne
Sharon OsbourneFrazer Harrison / Getty Images
Osbourne has been open about her weight struggles over the years and recently revealed that she had taken Ozempic to help manage her weight. However, she felt she lost too much weight and didn’t want to continue the medication.
“I lost 42 pounds now and it’s just enough,” she said during an episode of Piers Morgan’s podcast, per E! news. “I didn’t actually want to go this thin, but it just happened and I’ll probably put it all on again soon.”
She added that she experienced nausea as a side effect
“You don’t throw up physically but you’ve got that feeling,” she said. “I was about two, three weeks where I felt nauseous the whole time. You get very thirsty and you don’t want to eat. That’s it.”
Heather Gay
Heather Gay Monica Schipper / Getty Images
In November 2023, the “Real Housewives of Salt Lake City” star told People that she was “on the Ozempic train” and had been taking it “for a long time.”
“I haven’t had massive results, but enough for people to notice, which is great,” she added.
Chelsea Handler 
Chelsea Handler Axelle / Bauer-Griffin / FilmMagic
During a January 2023 appearance on the “Call Her Daddy” podcast, Chelsea Handler said that her anti-aging doctor “just hands (Ozempic) out to anybody.”
“I didn’t even know I was on it. She said, ‘If you ever want to drop 5 pounds, this is good,’” Handler recalled.
When the comedian returned from a vacation, she said decided to take an injection of the drug, not fully understanding what it was.
“I went to lunch with a girlfriend a few days later, and she was like, ‘I’m not really eating anything. I’m so nauseous, I’m on Ozempic,’” she said. “And I was like, ‘I’m kind of nauseous too.’ But I had just come back from Spain and was jet-lagged.”
At that point, Handler stopped using the medication.
“I’m an irresponsible drug user, but I’m not gonna take a diabetic drug,” she said. “I tried it, and I’m not going to do that. That’s not for me. That’s not right for me.”
Remi Bader 
Remi Bader Roy Rochlin / Getty Images
When she was pre-diabetic and gaining weight in 2020, Bader’s doctor recommended that she try Ozempic.
“They said I need this. And I had a lot of mixed feelings,” she told People in January 2023. “A few months later, I went off it and got into the bad binging.”
“It was making me think I wasn’t hungry for so long, I lost some weight,” she continued. “I didn’t want to be obsessed with being on it long term. I was like, I bet the second I got off I’m going get starving again. I did, and my binging got so much worse.”
Claudia Oshry 
Claudia OshryWWD via Getty Images
The social media personality was frank about her use of Ozempic in August 2023.
“You thought they were going to make a weight-loss drug and I wasn’t going to take it?” she said during an episode of her podcast, per People. “You’re dumb. Of course, I’m f—ing taking it.”
Oshry acknowledged that she was a “little embarrassed” when she first went on the drug.
“Like, ‘Oh my God, I have to inject myself with something just to get my fat a– to stop eating. Other people can do it without, why can’t I?’ In the beginning, my decision to not share was rooted in a little bit of shame,” she said.
Although she had success with Ozempic, Oshry was clear that she wasn’t trying to offer medical advice to anyone.
“It’s what’s working for me now. That’s the only reason I’ve been kind of hesitant to talk about it because I don’t want to be like, ‘I’ve figured it out. I’ve solved the problem for life.’ I have not,” she said.
She’s since revealed that she’s no longer on the medication and has since noticed some surprising changes in her body.
“I’m so hungry all the … time and I’m always looking for good treats because I’m still trying to lose weight but on my own,” she said in a March 2024 TikTok. “I’m always looking for snacks and things to fill me up.”
“I cannot stay full. It’s impossible,” she continued. “I just had a 12-ounce steak, and I’m starving so I’m eating popcorn. How are we staying full?”
Patti Stanger
Patti Stanger Vivien Killilea / Getty Images
In February 2023, “Millionaire Matchmaker” star Patti Stanger said that she has tried several medications for weight loss.
“I’m on the shot,” she said during an episode of the “Behind the Velvet Rope” podcast. “I’m going to tell you the truth. I went on semaglutide, which is the ingredient in Ozempic.”
Afterward, she experienced side effects and stopped taking the drug after three weeks. Then, Stanger tried Mounjaro. She didn’t experience the same side effects while taking this medication.
“I am not nauseous like everybody else,” she said.
Emily Simpson
Emily SimpsonTrae Patton / Bravo via Getty Images
Over the summer, the star of “The Real Housewives of Orange County” said she started taking Ozempic after learning that she was pre-diabetic and had high cholesterol.
“I (took Ozempic) in December for one month,” Simpson said, adding that it was a “great kickstart” and “worked amazing.”
The reality star lost between 5 and 7 pounds and said the drug made her “more conscientious of what I was eating.” But she stopped using it because of the side effects.
“It made me feel lethargic, and it made me just not have a lot of energy, which was hard with three little kids,” she said.
Dolores Catania
Dolores Catania Gabe Ginsberg / Getty Images
While chatting with Andy Cohen in April 2023, the star of “The Real Housewives of New Jersey” said she had been taking Ozempic.
“What housewife isn’t on Ozempic?” Cohen mused, per People.
“Not one … I wasn’t going to come to (the) reunion looking bigger than anyone else, so I got on the bandwagon,” she said.
Catania said she hadn’t experienced any negative side effects.
Lauren Manzo 
Lauren Manzo Matthew Eisman / Getty Images
After she was considered “morbidly obese” by a doctor, the “Real Housewives of New Jersey” alum said started taking Mounjaro. Per People, the reality star lost a significant amount of weight while taking the drug.
“Since February, I’ve lost 30 pounds from Mounjaro,” she said in May 2023 during a podcast episode. “And I get it — people don’t like it, people don’t applaud it, people aren’t whatever, but it’s a shot in your stomach once a week. … You guys have seen the struggle with this since I’m 20 years old, and it’s been really hard for me.”
Manzo said the drug has helped her more than other weight-loss methods.
“I mean, I’m not going lie, I feel like there have been times that I’ve been on the brink of an eating disorder or had issues myself. And this is the one thing — even above weight loss surgery — that has helped me a lot and cured me and mentally made me so much better. And I’m really grateful for it,” she said.
Golnesa ‘GG’ Gharachedaghi
Golnesa ‘GG’ Gharachedaghi
Greg Doherty / Bravo via Getty Images
In June 2023, the “Shahs of Sunset” star told her social media followers that she’d lost more weight than she intended to while taking Ozempic.
Per People, the star started off at 138 pounds and got down to 110 pounds after using the drug.
“Will I come off of it? Maybe. Will I gain it all back? Maybe. But for now, I’m enjoying the way I look. I’m enjoying what it’s doing for me,” she said. “I encourage it to anybody who’s having a hard time losing weight and wants the ‘easy route.’ Summer’s around the corner. I’m not trying to stress that being skinny is what you should do, but truth is, some of y’all want to do it. So I’m talking to you guys… not the f—ing haters.”
Luckily, Gharachedaghi said, she didn’t experience side effects, such as Ozempic face, from the rapid weight loss.
“As you can see, it did not affect my face. Yes, I do get fillers and Botox and all that but I haven’t gotten anything (recently). So just so you can see, it’s not sagging,” she said.
Charles Barkley 
Charles BarkleyRich Fury / Getty Images
The former NBA star shared on his CNN show “King Charles” that he lost 65 pounds while taking Mounjaro. But he’s been off it for about four months and has since gained 12 pounds back.
“There’s so many different ways to lose weight,” he said. “There’s no shoe size that fits all. But I gained 105 pounds … and a friend of mine says, ‘Yo, man, I want you to go to this doctor,’ because I can’t eat less and work out enough to lose 100 pounds.”
“And he says, try this drug. And I started taking Mounjaro. And I have lost 65 pounds. I started my journey at 355 pounds. I played at 250. … I’m down to 285.”
While Barkley said his doctor told him he’s now at a “good, healthy weight,” he’s hoping to go back on Mounjaro and lose another 15 pounds.
Billie Jean King
Billie Jean KingTim Clayton – Corbis / Corbis via Getty Images
During an April 2024 appearance on the “Wiser Than Me” podcast with Julia Louis-Dreyfus, the 80-year-old tennis great shared that she started taking Ozempic because she hoped it would help manage her eating disorder. She’s taken a few injections so far, she said.
“I’m a binge eater. Every morning I wake up, I tell myself, ‘I have an eating disorder,’” King explained. “I still go to therapy. I still think about it.”
“It’s two sides. Let’s say I want a quart of ice cream. One side will say, ‘Yeah, baby, I’m going to have that ice cream no matter what!’” she continued. “The other side says, ‘No, don’t do that. It’s not healthy. You know you don’t need it.’”
King shared that she started using Ozempic on her physician’s recommendation. Some people on the weight loss medication have reported that they think about food much less.
“If (weight-loss medication) does quiet the voices — if that’s a part of it — now I’m (interested in) it because that would be really great, because that gets exhausting and tiring. And I don’t want to fight over these things.”
She added that her goal for taking Ozempic is not to lose weight fast because “I think it looks horrible. … I would like to lose it slowly.”
Jon Gosselin
Jon GosselinPaul Archuleta / Getty Images
The “Jon & Kate Plus 8” alum spoke to Page Six on April 26, 2024 about his experience taking weight-loss medication.
Gosselin told the outlet that he only had one “regret” about the experience, explaining, “You know what’s annoying? The regret of not starting it 10 years ago.”
In February 2024, Gosselin began taking semaglutide in addition to undergoing testosterone replacement therapy. He told Page Six that since he started taking the drug, he has been able to lose 32 pounds in just two months.
“I feel amazing! Like, why didn’t I do this sooner? Maybe it wasn’t the right time,” Gosselin explained, before noting several factors in his personal life that may have affected his previous decisions.
He added, “A lot of things were going on emotionally and I went to court a lot, which was super expensive. It just wasn’t a good time in my life. But now I finally have time to focus on myself.”
In addition to aiding in Gosselin’s weight loss, he told the outlet that the drug helped with other aspects of his life, including forming better eating habits as well as giving up alcohol.
“It’s really nice because it helped me stop drinking and it helped me get my appetite under control with less eating,” he said. “I was able to really refocus my diet that way. I just focused on consuming what I need to consume in a healthy manner.”