Brock Purdy is “getting closer” to returning, says San Francisco 49ers head coach Kyle Shanahan, but it likely won’t be this week. The quarterback remained limited in practice this week having not played since Week 4 after aggravating a toe injury.
“I think we’re definitely being more aggressive with him as we go this week, more aggressive than last week,” Shanahan said, via David Bonilla of 49erswebzone.com. “He’s definitely getting better each week, heading in the right direction. Still haven’t decided this week whether we’d rule him out or not. We’ll probably do that tomorrow after practice, but Brock’s definitely getting closer.”
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Shanahan added that he’s “pretty confident” Purdy will return sometime this season. Mac Jones will make his eighth start as the 49ers take on the Los Angeles Rams.
There is some good news on Jayden Daniels’ elbow. The Washington Commanders quarterback will not need surgery after an MRI revealed that he does not have any ligament damage in the elbow.
Daniels will not be placed on injured reserve, which would have ruled him out for at least an additional four weeks. The Commanders will re-evaluate the second-year quarterback following the team’s bye in Week 12.
Multiple medical opinions were sought and the Commanders believe Daniels, who is reportedly “feeling a little sore,” could possibly return at some point this season.
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Daniels was injured during Sunday night’s loss to the Seattle Seahawks. Afterward, head coach Dan Quinn said the elbow was not broken, but was unsure of a timeline for return.
Other notable Week 10 injuries:
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Houston Texans quarterback C.J. Stroud will miss Week 10 after suffering a concussion last week against the Denver Broncos. Davis Mills will start in his place against the Jacksonville Jaguars.
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Saquon Barkley returned to practice with the Philadelphia Eagles after suffering a groin injury against the New York Giants in Week 8. Barkley sat out the remainder of that game as a precaution and had an extra week of rest with the Eagles on a bye last week. Head coach Nick Sirianni didn’t give an update on the running back’s Week 10 status, instead deferring to the team’s injury report when it’s released on Friday.
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Also back from their bye week are the Tampa Bay Buccaneers, who will not have the duo of running back Bucky Irving and wide receiver Chris Godwin Jr. for another week. Neither player practiced this week and they were ruled out Friday by head coach Todd Bowles. Godwin has missed three games with a fibula injury, while Irving has sat out four games as he deals with foot and shoulder injuries.
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After missing Philadelphia’s Week 8 win over the Giants with a hamstring injury, Eagles wide receiver A.J. Brown said he expects to play Monday night against the Green Bay Packers.
Jump to a team:
AFC East: Bills | Dolphins | Patriots | Jets
AFC North: Ravens | Bengals (bye) | Browns | Steelers
AFC South: Texans | Colts | Jaguars | Titans (bye)
AFC West: Broncos (played Thurs.) | Chiefs (bye) | Raiders (played Thurs.) | Chargers
NFC East: Cowboys (bye) | Giants | Eagles | Commanders
NFC North: Bears | Lions | Packers | Vikings
NFC South: Falcons | Panthers | Saints | Buccaneers
NFC West: Cardinals | Rams | 49ers | Seahawks
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Here’s the rest of the Week 10 injury report (players will be added as teams release their reports):
ATLANTA FALCONS
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EDGE Leonard Floyd (hamstring): OUT
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G Matthew Bergeron (ankle): OUT
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OL Storm Norton (foot): OUT
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CB Mike Hughes (neck): questionable
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G Chris Lindstrom (foot): questionable
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DT LaCale London (shoulder): questionable
INDIANAPOLIS COLTS
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DE DeForest Buckner (neck): OUT
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DE Samson Ebukam (knee): OUT
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DE Tyquan Lewis (groin): OUT
JACKSONVILLE JAGUARS
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WR Brian Thomas Jr. (ankle): OUT
HOUSTON TEXANS
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QB C.J. Stroud (concussion): OUT
NEW ORLEANS SAINTSCAROLINA PANTHERS
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G Chandler Zavala (elbow): OUT
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WR Brycen Tremayne (hip): questionable
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WR Tetairoa McMillan (hamstring): questionable
NEW ENGLAND PATRIOTS
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RB Rhamondre Stevenson (toe): OUT
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WR Kayshon Boutte (hamstring): OUT
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LB Christian Elliss (hip): OUT
TAMPA BAY BUCCANEERS
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WR Chris Godwin Jr. (fibula): OUT
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RB Bucky Irving (foot, shoulder): OUT
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OLB Haason Reddick (ankle, knee): OUT
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OLB Markees Watts (hand): OUT
CLEVELAND BROWNS
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WR Isaiah Bond (foot): OUT
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WR Cedric Tillman (hamstring): questionable
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TE Harold Fannin Jr. (hamstring): questionable
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LB Carson Schwesinger (ankle): questionable
NEW YORK JETSBALTIMORE RAVENSMINNESOTA VIKINGSBUFFALO BILLS
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DL AJ Epenesa (concussion): OUT
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LB Shaq Thompson (hamstring): OUT
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DT DaQuan Jones (calf): questionable
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WR Josh Palmer (knee, ankle): questionable
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CB Taron Johnson (groin): questionable
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CB Christian Benford (groin): questionable
MIAMI DOLPHINSNEW YORK GIANTSCHICAGO BEARSARIZONA CARDINALS
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QB Kyler Murray (foot): OUT
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LB Mack Wilson (ribs): OUT
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CB Max Melton (concussion): OUT
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CB Will Johnson (back, hip): OUT
SEATTLE SEAHAWKSDETROIT LIONSWASHINGTON COMMANDERS
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QB Jayden Daniels (elbow): OUT
LOS ANGELES RAMSSAN FRANCISCO 49ERSPITTSBURGH STEELERSLOS ANGELES CHARGERSPHILADELPHIA EAGLESGREEN BAY PACKERSNFL injury updates liveLive5 updates
Fri, November 7, 2025 at 12:19 PM CST
Sean Leahy
Shedeur Sanders will return to his role as Dillon Gabriel’s backup for Sunday’s game against the Jets.
The Browns quarterback sat out their Week 9 loss to the Patriots with tightness in his back. Following their bye last week, Sanders resumed practicing this past Wednesday.
Fri, November 7, 2025 at 12:00 PM CST
Andy Backstrom
The Indianapolis Colts announced Friday that they have placed defensive tackle DeForest Buckner on injured reserve with a neck injury.
Now that Buckner is on IR, he will have to miss a minimum of four games. The three-time Pro Bowler sustained the injury during a Week 9 loss to the Pittsburgh Steelers, according to Colts head coach Shane Steichen.
Sean Leahy
Daniels suffered a dislocated elbow during last week’s loss to the Seahawks. The Commanders have yet to announce any sort of timeline for a return or if he will play again this season.
According to ESPN’s John Keim, Daniels will not need surgery on the elbow and is only “feeling a little sore.”
The Commanders have their bye in Week 12 after playing the Lions this week and the Dolphins next Sunday.
Sean Leahy
Wilson suffered a knee injury during the Week 6 loss to the Broncos in London.
Sean Leahy
Nacua left Sunday’s win over the Saints with a rib injury. Scans came back negative and he began the week practicing in a limited fashion. He was upgraded on Thursday and should play against the 49ers.