Longevity is no longer niche—it’s the new luxury. The modern wellness status symbol. And two therapies have emerged as quiet power players shaping the conversation: NAD+ and GLP-1s. The former fuels cellular energy and repair, while the latter regulates appetite, inflammation and metabolic balance. Together, they’ve become the duo people turn to for feeling better, aging smarter and staying energized.

Featured Experts

  • Dr. Jessie Cheung is a board-certified dermatologist in Willowbrook, IL
  • Dr. Amanda Kahn is a board-certified internist and longevity expert in New York

Why NAD+ Is Having a Moment

Willowbrook, IL dermatologist Jessie Cheung, MD explains why NAD+ has captured so much attention. “It helps with our energy production, helps with our DNA repair and helps with our longevity genes,” she says. New York internist Amanda Kahn, MD calls it “a great coenzyme that helps rejuvenate your cells from the inside out.”

GLP-1s and Inflammation

GLP-1 therapy works differently but fits perfectly into the longevity space. Dr. Cheung says it is not just about weight loss. “We love GLPs because they are great for inflammation. We know the root of aging is inflammation,” she says. She has been on a GLP-1 for five years and says simply, “I just feel better.”

Why This Duo Works

When used together the benefits align. NAD+ supports the cells so they function with more resilience. GLP-1s support the larger metabolic systems that guide appetite and inflammation. The result is a more balanced internal environment that helps people feel clearer lighter more aligned.

Dr. Cheung says NAD+ is “an easy biohack to get started with” and adds that pairing it with GLP-1 therapy “helps to power that system of living better.”

To take results even further, Dr. Kahn often pairs NAD+ with GHK peptide injections, which she says “rebuild your skin from the inside out” and injectable glutathione, which she calls “a master antioxidant” that sweeps away free radicals and helps protect cells from aging.

As Dr. Cheung reminds us the most underrated longevity tool is still the simplest. “Relaxing is the answer.” In a world obsessed with optimization, that might just be the ultimate luxury.