Rare Mutation Shields Brain from Alzheimer’s by Silencing Inflammation
Summary: A rare genetic mutation known as APOE3-R136S, or the “Christchurch mutation,” appears to protect against Alzheimer’s disease…
Rare Gene Mutation Delays Alzheimer’s by Damping Immune Cell Inflammatory Signaling
Pathological phosphorylation (yellow) of Tau proteins (red-orange) by kinases (violet) leads to disintegration of microtubules in the neuron…