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Browsing Tag

Animal Genetics and Genomics

22 posts
HHealth
TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages
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TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages

  • November 7, 2025
Cañellas-Socias, A., Sancho, E. & Batlle, E. Mechanisms of metastatic colorectal cancer. Nat. Rev. Gastroenterol. Hepatol. 21, 609–625…
GGenetics
Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs
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Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs

  • October 21, 2025
Cohorts We used published data (GEO accession no. GSE162632) to study the effect of 12 h of ex vivo…
GGenetics
FT-like genes in Cannabis and hops: sex specific expression and copy-number variation may explain flowering time variation | BMC Genomics
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FT-like genes in Cannabis and hops: sex specific expression and copy-number variation may explain flowering time variation | BMC Genomics

  • October 19, 2025
Melzer R, McCabe PF, Schilling S. Evolution, genetics and biochemistry of plant cannabinoid synthesis: a challenge for biotechnology…
GGenetics
Redefining cellular reprogramming with advanced genomic technologies
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Redefining cellular reprogramming with advanced genomic technologies

  • October 18, 2025
Briggs, R. & King, T. J. Transplantation of living nuclei from blastula cells into enucleated Frogs’ eggs. Proc.…
GGenetics
SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology
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SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology

  • October 16, 2025
Model residuals of linear regression and logistic regression Linear regression and logistic regression are regular models to fit…
GGenetics
KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease
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KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease

  • October 13, 2025
Precision Healthcare University Research Institute, Queen Mary University of London, London, UK Segun Fatumo, Oyesola Ojewunmi, Rebecca Camenzuli, Christopher Kintu & Claudia Langenberg…
GGenetics
Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health
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Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health

  • October 11, 2025
To identify genes associated with either adult BMI or T2D risk, we performed association testing using WGS data…
GGenetics
A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology
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A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology

  • October 10, 2025
K-proportion and gene homeostasis Z-Index identify regulatory genes As cells of the same type and in the same…
GGenetics
Exploring the genetic basis of heterosis in eucalypt growth based on transcriptome analysis | BMC Genomics
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Exploring the genetic basis of heterosis in eucalypt growth based on transcriptome analysis | BMC Genomics

  • October 3, 2025
Preparation of preliminary data In all samples, the proportion of clean reads was higher than 99.5% (Table S2),…
GGenetics
Large-scale screening of genes responsible for silique length and seed size in Brassica Napus via pooled CRISPR library | BMC Genomics
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Large-scale screening of genes responsible for silique length and seed size in Brassica Napus via pooled CRISPR library | BMC Genomics

  • September 26, 2025
Selection and integration of candidate genes governing silique and seed size To identify candidate genes modulating silique length…
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