Sex and smoking bias in the selection of somatic mutations in human bladder
Sample collection Two epithelial brushes (2–3 cm2) from the bladder top (dome) and the bladder floor (trigone) were obtained…
Somatic mutation and selection at population scale
Cohort selection The TwinsUK study contains around 16,000 participants. From a preselection of 4,800 donors, we invited 1,796…
Tracking clonal evolution during treatment in ovarian cancer using cell-free DNA
Sample collection All enrolled patients were consented to an institutional biospecimen banking protocol and MSK-IMPACT testing42, and all…
Direct letters to relatives at risk of hereditary cancer—a randomised trial on healthcare-assisted versus family-mediated risk disclosure
Study context The management of genetic testing results and consequent risk information is not explicitly addressed in Swedish…