AAV gene therapy for autosomal recessive deafness 9: a single-arm trial
Chang, Q. et al. Virally mediated Kcnq1 gene replacement therapy in the immature scala media restores hearing in…
North Texas Researchers Develop New Tool That Uncovers Disease-Driving Gene Switches » Dallas Innovates
Xinlei (Sherry) Wang, Jenkins Garrett professor of statistics and data science at UTA, says understanding these gene regulators…
How chemotherapy shapes hematopoietic stem cells
Welch, J. S. et al. Cell 150, 264–278 (2012). Article CAS PubMed PubMed Central Google Scholar Mitchell, E.…
Exercise therapy and self-management support for individuals with multimorbidity: a randomized and controlled trial
Study design This was a pragmatic, assessor-blinded, multicenter, parallel-group RCT (1:1 treatment allocation) with follow-up assessments at 4,…
Health effects associated with consumption of processed meat, sugar-sweetened beverages and trans fatty acids: a Burden of Proof study
Monteiro, C. A. et al. Ultra-processed foods: what they are and how to identify them. Public Health Nutr.…
Structural variants in the 3D genome as drivers of disease
Kaschta, D. et al. Evaluating genome sequencing strategies: trio, singleton, and standard testing in rare disease diagnosis. Preprint…
How and when organisms edit their own genomes
Lindahl, T. Instability and decay of the primary structure of DNA. Nature 362, 709–715 (1993). Article CAS PubMed …
UT Health San Antonio receives $3.4M for cancer research and HPV vaccination efforts
SAN ANTONIO — The Cancer Prevention and Research Institute of Texas has awarded nearly $3.4 million to UT…
AAV mini-dystrophin gene therapy for Duchenne muscular dystrophy: a phase 1b trial
Study design and oversight This ongoing, nonrandomized, open-label, ascending-dose, phase 1b study (ClinicalTrials.gov registration no. NCT03362502) was initiated…
Dallas-Based Susan G. Komen Awards $10.8M in New Breast Cancer Research Grants » Dallas Innovates
Susan G. Komen, the breast cancer organization headquartered in Dallas, is awarding $10.8 million in a new round…