p21+TREM2+ senescent macrophages fuel inflammaging and metabolic dysfunction-associated steatotic liver disease
Exogenous DNA damage drives Cdkn1a (p21)+ senescence in macrophages in vitro To test whether macrophages can undergo an…
Digitally native species are a necessary shift in taxonomic practice
Bánki, O. et al. Catalogue of Life (2025-11-16 XR) (Catalogue of Life Foundation, 2025); https://doi.org/10.48580/dgvbl. Miralles, A. et…
Systemic epigenetic dysregulation as a driver of ageing and a therapeutic target
Guo, J. et al. Aging and aging-related diseases: from molecular mechanisms to interventions and treatments. Signal. Transduct. Target.…
Ajaya Bio plans Series A for autoimmune drug development
Startup profile: Ajaya Bio Founded by: Mohit Sachdeva, Ramesh Singh Year founded: 2024 Headquarters: Philadelphia, PA Sector: Biotech…
Lincoln Plans Spec Office, Lab In Houston. It Just Needs A Lender
Developing a speculative office building in one of the country’s most vacant office markets may not sound desirable…
Sugar Land Rolls Out Incentives To Attract Startups, Upgrade Offices
One of the most built-out suburbs in the Houston area is using taxpayer-funded incentives to capitalize on the region’s life…
Plasmids promote antimicrobial resistance through insertion sequence-mediated gene inactivation
Ho, C. S. et al. Antimicrobial resistance: a concise update. Lancet Microbe 6, 100947 (2025). Article PubMed Google…
Dietary restriction in aging and longevity
Weindruch, R. & Walford, R. L. Dietary restriction in mice beginning at 1 year of age: effect on…
High-throughput phenomics of global ant biodiversity
Meineke, E. K., Davies, T. J., Daru, B. H. & Davis, C. C. Biological collections for understanding biodiversity…
A new after-school life sciences program is coming to Philadelphia
This is How I Got Here, a series where we chart the career journeys of technologists. Want to tell…