Prospective evaluation of genomics-guided off-label treatment
Over the past nine years, DRUP provided opportunities for off-label treatment to more than 1,600 patients with advanced…
Identifying the topographic signature of early Martian oceans
Our work relies on three datasets: (1) global digital elevation models and bathymetric data for both Earth and…
Brainwide blood volume reflects opposing neural populations
Brainwide fUSI measurements Experiments were conducted in 5 C57/BL6 mice (3 male, 2 female), 13–34 weeks of age.…
A spatial atlas of the healthy human liver from live donors
Experimental methodsHuman sample preparation Human samples and clinical data were obtained from patients undergoing either hepatectomy surgery due…
A mechanism for adaptive genome regulation in cancer
Llinás, R. R. The contribution of Santiago Ramón y Cajal to functional neuroscience. Nat. Rev. Neurosci. 4, 77–80…
Language models transmit behavioural traits through hidden signals in data
Experimental setup: distillation on an unrelated domain This section describes the structure of our main experiments (Fig. 2).…
Landmark ancient-genome study shows surprise acceleration of human evolution
Some gene variants became consistently more or less frequent over time in ancient human populations — a sign…
Cell-type-targeted mitochondrial transplantation rescues cell degeneration
Animals Animal experiments were performed following standard ethical guidelines (European Communities Guidelines on the Care and Use of…
Ancient DNA reveals pervasive directional selection across West Eurasia
Liu, Y., Mao, X., Krause, J. & Fu, Q. Insights into human history from the first decade of…
Imaging interface-controlled bulk oxygen spillover
Conner, W. C. Jr. & Falconer, J. L. Spillover in heterogeneous catalysis. Chem. Rev. 95, 759–788 (1995). Article …