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Browsing Tag

Neurosciences

18 posts
GGenetics
Insights into ancestral diversity in Parkinson’s disease risk: a comparative assessment of polygenic risk scores
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Insights into ancestral diversity in Parkinson’s disease risk: a comparative assessment of polygenic risk scores

  • July 3, 2025
Programa de Pós-Graduação em Ciências Médicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil Paula Saffie-Awad & Artur…
GGenetics
AAV gene therapy for autosomal recessive deafness 9: a single-arm trial
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AAV gene therapy for autosomal recessive deafness 9: a single-arm trial

  • July 2, 2025
Chang, Q. et al. Virally mediated Kcnq1 gene replacement therapy in the immature scala media restores hearing in…
FFitness
Exercise therapy and self-management support for individuals with multimorbidity: a randomized and controlled trial
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Exercise therapy and self-management support for individuals with multimorbidity: a randomized and controlled trial

  • July 1, 2025
Study design This was a pragmatic, assessor-blinded, multicenter, parallel-group RCT (1:1 treatment allocation) with follow-up assessments at 4,…
NNutrition
Health effects associated with consumption of processed meat, sugar-sweetened beverages and trans fatty acids: a Burden of Proof study
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Health effects associated with consumption of processed meat, sugar-sweetened beverages and trans fatty acids: a Burden of Proof study

  • June 30, 2025
Monteiro, C. A. et al. Ultra-processed foods: what they are and how to identify them. Public Health Nutr.…
GGenetics
AAV mini-dystrophin gene therapy for Duchenne muscular dystrophy: a phase 1b trial
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AAV mini-dystrophin gene therapy for Duchenne muscular dystrophy: a phase 1b trial

  • June 27, 2025
Study design and oversight This ongoing, nonrandomized, open-label, ascending-dose, phase 1b study (ClinicalTrials.gov registration no. NCT03362502) was initiated…
GGenetics
Genome-wide association meta-analysis and rare copy number variant analysis of treatment-resistant depression
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Genome-wide association meta-analysis and rare copy number variant analysis of treatment-resistant depression

  • June 26, 2025
GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived…
GGenetics
Unraveling time-dependent genetic components underlying alcohol response
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Unraveling time-dependent genetic components underlying alcohol response

  • June 21, 2025
World Health Organization. Alcohol: Fact sheet. 2018. https://www.who.int/en/news-room/fact-sheets/detail/alcohol. Accessed February 2 2022. Hurley TD, Edenberg HJ. Genes encoding…
GGenetics
Clinical progression and genetic pathways in body-first and brain-first Parkinson’s disease | Molecular Neurodegeneration
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Clinical progression and genetic pathways in body-first and brain-first Parkinson’s disease | Molecular Neurodegeneration

  • June 20, 2025
Study participants We analysed data from 1120 clinically diagnosed and 910 prodromal Parkinson’s disease (PD) individuals enrolled in…
United States
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