{"id":18904,"date":"2025-06-27T11:16:12","date_gmt":"2025-06-27T11:16:12","guid":{"rendered":"https:\/\/www.europesays.com\/us\/18904\/"},"modified":"2025-06-27T11:16:12","modified_gmt":"2025-06-27T11:16:12","slug":"diagnosis-research-and-whats-ahead","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/us\/18904\/","title":{"rendered":"Diagnosis, Research, and What\u2019s Ahead"},"content":{"rendered":"<p><img decoding=\"async\" class=\"m-auto absolute inset-0 max-w-[0%] max-h-[0%] border-[3px] border-solid border-white shadow-[0px_0px_8px_rgba(0,0,0,0.3)] box-border transition ease-in-out duration-500\" src=\"https:\/\/www.europesays.com\/us\/wp-content\/uploads\/2025\/06\/e2672eb7679c01c99859d6cec906ccd33eb54ccb-300x300.png\"\/><\/p>\n<p class=\"pb-2\"><strong>Episode 144 of the NeurologyLive\u00ae\u00a0<a rel=\"nofollow noopener\" target=\"_self\" href=\"http:\/\/audioboom.com\/channels\/5001429\">Mind Moments<\/a>\u00ae<a rel=\"nofollow noopener\" target=\"_self\" href=\"http:\/\/audioboom.com\/channels\/5001429\"> podcast<\/a> is now live! Scroll down to listen or <a rel=\"nofollow noopener\" target=\"_self\" href=\"http:\/\/audioboom.com\/channels\/5001429\">click here<\/a> to subscribe on your favorite streaming service.<\/strong><\/p>\n<p class=\"pb-2\">The Mind Moments podcast features exclusive interviews with leaders in the field discussing the latest research and disease management strategies across the breadth of neurology, including epilepsy, multiple sclerosis, Parkinson disease, dementia, sleep disorders, and more.<\/p>\n<p class=\"pb-2\">In this episode, &#8220;Differentiating Dravet and Lennox-Gastaut: Diagnosis, Research, and What\u2019s Ahead<strong>,<\/strong>&#8221; Joseph Sullivan, MD, director of the Pediatric Epilepsy Center at UCSF, joins Mind Moments to discuss the clinical distinctions between Dravet syndrome (DS) and Lennox-Gastaut syndrome (LGS). Sullivan outlines the unique diagnostic profiles, seizure presentations, and genetic underpinnings of each disorder, while also addressing how genetic testing has transformed the approach to DS in particular. He speaks on the future of targeted therapies, highlighting ongoing research in disease-modifying treatments and n-of-1 trials, especially for ultra-rare epilepsies. Additionally, Sullivan explores how the clinical trial landscape is evolving\u2014emphasizing the need for biomarkers, innovative trial design, and better tools for seizure monitoring to improve outcomes in these complex pediatric epilepsies.<\/p>\n<p class=\"pb-2\">The stories featured in this week&#8217;s Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here:<\/p>\n<\/p>\n<p><strong>EPISODE BREAKDOWN<\/strong><\/p>\n<ul class=\"my-2\">\n<li class=\"list-disc ml-8\"><strong>1:00<\/strong> \u2013 Key differences in phenotype and diagnosis between Dravet syndrome and LGS<\/li>\n<li class=\"list-disc ml-8\"><strong>3:50<\/strong>\u2013 The evolution of genetic testing and how it\u2019s improved Dravet diagnosis and outcomes<\/li>\n<li class=\"list-disc ml-8\"><strong>6:25<\/strong> \u2013 Opportunities and limitations in scaling genetic testing more broadly<\/li>\n<li class=\"list-disc ml-8\"><strong>8:05<\/strong> \u2013 Neurology News Minute<\/li>\n<li class=\"list-disc ml-8\"><strong>10:10<\/strong> \u2013 Research pipelines: disease-modifying therapies, n-of-1 trials, and future directions<\/li>\n<li class=\"list-disc ml-8\"><strong>13:10<\/strong> \u2013 Innovations in clinical trial design and the need for better seizure monitoring and biomarkers<\/li>\n<\/ul>\n<p class=\"pb-2\"><a rel=\"nofollow noopener\" target=\"_self\" href=\"https:\/\/audioboom.com\/channels\/5001429\">Click here<\/a> to subscribe to the Mind Moments podcast. Be sure to leave a rating and review for the show. Thanks for listening!<\/p>\n<p class=\"pb-2\">Hoping to listen on your favorite podcast app? See below:<\/p>\n","protected":false},"excerpt":{"rendered":"Episode 144 of the NeurologyLive\u00ae\u00a0Mind Moments\u00ae podcast is now live! Scroll down to listen or click here to&hellip;\n","protected":false},"author":3,"featured_media":18905,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[815,17862,17863,17864,5158,159,67,132,68],"class_list":{"0":"post-18904","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-genetics","8":"tag-genetics","9":"tag-mind-moments","10":"tag-mind-moments-podcast","11":"tag-neurologylive-podcast","12":"tag-podcasts","13":"tag-science","14":"tag-united-states","15":"tag-unitedstates","16":"tag-us"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@us\/114755048778256478","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/posts\/18904","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/comments?post=18904"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/posts\/18904\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/media\/18905"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/media?parent=18904"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/categories?post=18904"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/tags?post=18904"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}