![\"It's](\"https:\/\/www.europesays.com\/us\/wp-content\/uploads\/2025\/06\/Screenshot_2025-06-20_102040_1750395052251_1750395080473.png\" "\\"It's")
It’s crucial to consult with your healthcare provider to determine the best approach for managing allergies while staying active. (Representative picture: Freepik) What is histamine and why does it matter?<\/p>\n
The molecule histamine \u2013 often linked to seasonal allergies like runny noses, scratchy throats, and itchy eyes \u2013 also influences exercise performance. The University of Oregon study underscores its beneficial role in aerobic activity and exercise recovery, showing that blocking histamine at high levels interferes with fitness gains.<\/p>\n
\u201cIn exercise, it actually seems to be playing a very similar role of facilitating our adaptation to stress,\u201d said John Halliwill, a professor of human physiology at the University of Oregon and an author on the study. He and colleagues found that when histamine is blocked, aerobic fitness improvements were slashed in half.<\/p>\n
Histamine also seems to boost the response of certain genes during exercise. When histamine is blocked, about a quarter of those 3,000 or so genes aren\u2019t amplified. That means fewer new proteins get produced by muscles as they recover from exercise, and those proteins likely play key roles in fitness gains, like the ones measured in the study.<\/p>\n
More about the study<\/p>\n
The researchers compared the improvements in a group of 16 men and women participating in a six-week biking regimen. Participants pedalled on stationary bikes three to four times a week over the course of the study. One group received a dose of antihistamine medication before each training session, while the other group took a placebo.\u00a0<\/p>\n
Then, researchers compared how the groups\u2019 bodies adapted. When it came to their actual performance \u2014 how hard they could bike \u2014 the placebo group saw about twice the improvement of the histamine-blocker group. Improvements in blood flow were also significantly higher in the placebo group.<\/p>\n
Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.<\/p>\n
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