{"id":311051,"date":"2025-10-17T15:38:11","date_gmt":"2025-10-17T15:38:11","guid":{"rendered":"https:\/\/www.europesays.com\/us\/311051\/"},"modified":"2025-10-17T15:38:11","modified_gmt":"2025-10-17T15:38:11","slug":"why-san-diego-is-one-of-the-best-cities-for-longevity","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/us\/311051\/","title":{"rendered":"Why San Diego Is One of the Best Cities for Longevity"},"content":{"rendered":"<p>Early on a Saturday morning, the surf at <a href=\"https:\/\/sandiegomagazine.com\/guides\/san-diego-neighborhood-guide-la-jolla\/\" rel=\"nofollow noopener\" target=\"_blank\">La Jolla Cove<\/a> is dotted with swimmers slicing through the Pacific in steady strokes. On the steps above, a group of retirees laughs through a <a href=\"https:\/\/sandiegomagazine.com\/features\/kroc-center-senior-aquatics-exercise\/\" rel=\"nofollow noopener\" target=\"_blank\">bodyweight circuit<\/a>, while <a href=\"https:\/\/sandiegomagazine.com\/things-to-do\/best-hikes-southern-california\/#:~:text=Torrey%20Pines%20State%20Reserve%20Loop%2C%20La%20Jolla\" rel=\"nofollow noopener\" target=\"_blank\">hikers gather at Torrey Pines<\/a> to start their sunrise trek. And a mile inland, scientists are decoding the biology of aging, zeroing in on everything from gene expression to mitochondrial function. This is where the future of aging is being written.<\/p>\n<p>All of these things combine to make San Diego one of the nation\u2019s <a href=\"https:\/\/www.amraandelma.com\/us-cities-with-longest-life-expectancies\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">top-ranking cities for life expectancy<\/a>\u2014over 83 years on average, according to the CDC. But it\u2019s the research being done here that is changing the ways we understand humans\u2019 ability to live both longer and healthier. Across labs and clinics, the city\u2019s <a href=\"https:\/\/sandiegomagazine.com\/features\/winners-prebys-foundation-grants-2024\/\" rel=\"nofollow noopener\" target=\"_blank\">growing coalition of researchers<\/a> is turning the region into a proving ground for the next era of aging science, one rooted not in fantasies of immortality but in the pragmatic <a href=\"https:\/\/sandiegomagazine.com\/everything-sd\/biohacking-wellness-treatments-san-diego\/\" rel=\"nofollow noopener\" target=\"_blank\">pursuit of vitality<\/a>.<\/p>\n<p>\u201cSan Diego is way ahead when it comes to longevity,\u201d says Satchin Panda, PhD, director of the Regulatory Biology Laboratory at the <a href=\"https:\/\/www.salk.edu\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Salk Institute<\/a>. \u201cWe have the ideal climate, a health-conscious population, and a community that\u2019s curious. That makes it easier to study what works in real life, not just in the lab.\u201d<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"1000\" src=\"https:\/\/www.europesays.com\/us\/wp-content\/uploads\/2025\/10\/0X8C2828.jpg.webp.webp\" alt=\"Satchin Panda, PhD, director of the Regulatory Biology Laboratory at the Salk Institute\" class=\"wp-image-115739\"   data-mwl-img-id=\"115739\"\/>Courtesy of the Salk Institute<br \/>Dr. Satchin Panda\u2019s research has shown that eating within a 10-hour window can have dramatic positive health consequences.<\/p>\n<p>This culture of curiosity has cultivated fertile ground for <a href=\"https:\/\/sandiegomagazine.com\/features\/salk-institute-harnessing-plants-initiative\/\" rel=\"nofollow noopener\" target=\"_blank\">world-class research<\/a> and record-breaking investment. In 2023 alone, the region secured $1.23 billion in National Institutes of Health funding, ranking fourth in the nation, and its life science companies raised $6.8 billion in venture capital, the highest per-capita investment in the US. With local institutions like Salk, <a href=\"https:\/\/sandiegomagazine.com\/features\/ucsd-home-health-and-ai\/\" rel=\"nofollow noopener\" target=\"_blank\">UCSD<\/a>, <a href=\"https:\/\/sandiegomagazine.com\/features\/scripps-health-100th-anniversary\/\" rel=\"nofollow noopener\" target=\"_blank\">Scripps<\/a>, and Sanford Burnham Prebys driving collaboration, discovery moves fast.<\/p>\n<p>Panda is known for work that connects everyday habits with scientific discovery. \u201cMost aging research focuses on what to eat,\u201d Panda says, \u201cbut our lab has shown that when you eat can shape expression of the human genome.\u201d He\u2019s discovered that eating within a consistent 10-hour window doesn\u2019t just help with weight management, it also improves sleep, blood pressure, and even emotional well-being. His work, funded in part by local philanthropists and tested in everyday settings from firefighters\u2019 kitchens to family homes, has helped catapult time-restricted eating into mainstream longevity conversations. \u201cJust changing the timing of food can orchestrate thousands of genes, syncing the body like a finely tuned symphony,\u201d he adds.<\/p>\n<p>He often conducts his studies in collaboration with first responders. \u201cWe worked with the <a href=\"https:\/\/www.sandiego.gov\/fire\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">San Diego Fire Department<\/a> to study eating windows for shift workers. These are people with some of the toughest health stressors, and yet the results were striking,\u201d Panda says. When they ate within a 10-hour window, they reduced their risk for chronic disease and even cancer without changing what they ate.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"1000\" src=\"https:\/\/www.europesays.com\/us\/wp-content\/uploads\/2025\/10\/MooreAlison-202409-1.jpg.webp.webp\" alt=\"Alison Moore, MD, MPH, FACP and director of UC San Diego\u2019s Stein Institute for Research on Aging\" class=\"wp-image-115741\"   data-mwl-img-id=\"115741\"\/>Photo Credit: Kyle C. Dykes\/University of California San Diego Health Sciences<br \/>Alison A. Moore, MD; MPH<\/p>\n<p>This kind of actionable science is what San Diego does best. \u201cWe are seeing more research on the drivers of healthy aging across biological, behavioral, social, and environmental domains,\u201d says <a href=\"https:\/\/providers.ucsd.edu\/details\/32626\/primary-care-senior-medicine\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Alison A. Moore<\/a>, MD; MPH; chief of geriatrics, gerontology, and palliative care; and director of UC San Diego\u2019s <a href=\"https:\/\/sira.ucsd.edu\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Stein Institute for Research on Aging<\/a>. Moore has spent her career understanding how people can age not just longer but better. She notes that exercise, diet, sleep, and social engagement consistently stand out as key factors.<\/p>\n<p>\u201cSan Diego\u2019s geographic and demographic diversity, enriched by our <a href=\"https:\/\/sandiegomagazine.com\/everything-sd\/places-we-love-san-diego-tijuana-book\/\" rel=\"nofollow noopener\" target=\"_blank\">proximity to Mexico<\/a>, offers a rare chance to study aging across rural, urban, and suburban communities, including <a href=\"https:\/\/sandiegomagazine.com\/features\/diverse-research-now-medical-trials\/\" rel=\"nofollow noopener\" target=\"_blank\">groups often left out of biomedical research<\/a>,\u201d Moore says. \u201cThe insights we gain here have the potential to shape how healthy aging is understood worldwide.\u201d<\/p>\n<p>The Stein Institute\u2019s initiatives\u2014 like the <a href=\"https:\/\/www.who.int\/data\/data-collection-tools\/study-on-global-ageing-and-adult-health\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">SAGE longitudinal study<\/a>, which follows older adults over decades to reveal patterns in health and resilience, and the <a href=\"https:\/\/healthyaging.ucsd.edu\/research\/living-lab-belmont\/index.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Living Lab at Belmont Village<\/a> in La Jolla, a community-based hub where senior residents partner with researchers to study aging in daily life\u2014provide ongoing insights into how real people navigate aging. \u201cOur geroscience clinical research facility now lets us test promising interventions with cutting-edge biomarkers and rigorous clinical trials,\u201d Moore says. \u201cWe\u2019re finally in a position to see what truly works and what doesn\u2019t.\u201d At the Living Lab, that means working directly with residents to observe how factors such as diet, exercise, and social connection influence aging outside the clinic.<\/p>\n<p>UCSD has partnered with local artists and medical students, exploring how creativity and empathy influence age-related stigma. The institute teamed up with the <a href=\"https:\/\/sandiegomagazine.com\/things-to-do\/san-diego-museums-to-visit\/#:~:text=Art%20San%20Diego-,Museum%20of%20Contemporary%20Art%20San%20Diego,-It%E2%80%99s%20hard%20to\" rel=\"nofollow noopener\" target=\"_blank\">Museum of Contemporary Art San Diego<\/a> on a project to enhance arts education for older adults, reduce ageism in museums through larger-print and audio guides, and teach medical students empathy through art. \u201cWe want the science to meet people where they are, in their homes, their communities, their stories,\u201d Moore adds.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"1000\" src=\"https:\/\/www.europesays.com\/us\/wp-content\/uploads\/2025\/10\/Wet_lab_Topol_6.jpg.webp.webp\" alt=\"\" class=\"wp-image-115740\"   data-mwl-img-id=\"115740\"\/>Courtesy of Scripps Research<br \/>Dr. Eric Topol (in blue gingham) studies \u201cSuperAgers,\u201d older adults in exceptionally good health. He\u2019s found that factors like sleep and socializing are key to aging well.<\/p>\n<p>On the forefront of tech-driven aging solutions is cardiologist Dr. Eric Topol, the founder and director of the <a href=\"https:\/\/www.scripps.edu\/science-and-medicine\/translational-institute\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Scripps Research Translational Institute<\/a>. He points to rapid <a href=\"https:\/\/sandiegomagazine.com\/features\/artificial-intelligence-in-healthcare\/\" rel=\"nofollow noopener\" target=\"_blank\">advances in AI<\/a>, proteomics (the large-scale study of proteins and their role in health and disease), and aging clocks as \u201ca new frontier for preventing age-related diseases like Alzheimer\u2019s, cancer, and heart disease before they even manifest.\u201d<\/p>\n<p>Topol emphasizes that lifestyle remains foundational. His research on \u201cSuperAgers,\u201d older adults who maintain exceptional physical and cognitive health, underscores that factors such as quality sleep, avoiding ultra-processed foods, social engagement, and daily time in nature are \u201cpowerful, proven levers for extending healthspan, [the period of our lives where we\u2019re free from disability and chronic disease],\u201d he says. \u201cThe science of aging is evolving fast, but the strongest evidence still comes from how we live our daily lives.\u201d<\/p>\n<p>Though, soon, it may be possible for us to turn back the clocks. Daniel Oliver, co-founder and CEO of <a href=\"https:\/\/rejuvenatebio.com\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Rejuvenate Bio<\/a>, is one of the entrepreneurs pushing the healthspan frontier. His company is using <a href=\"https:\/\/sandiegomagazine.com\/features\/popular-medical-questions-answered-by-doctors\/#:~:text=What%20are%20some%20of%20the%20latest%20breakthroughs%20in%20the%20field%20of%20heart%20disease%20treatment%2C%20and%20what%20innovations%20will%20we%20see%20in%20the%20future%3F\" rel=\"nofollow noopener\" target=\"_blank\">gene therapy<\/a> to target the root causes of aging-related diseases. \u201cWe\u2019re looking at how we can reprogram cells to behave like they did in youth,\u201d he explains. \u201cThe idea is to treat aging at the molecular level, reversing the aging state and rejuvenating the tissue.\u201d<\/p>\n<p>Rejuvenate Bio\u2019s animal studies have shown promising results in reversing heart failure and diabetes in dogs. The company\u2019s human clinical trials are expected to launch soon. \u201cDogs are a great model for humans: They share our environments and our diseases, and they age faster than humans,\u201d Oliver says. \u201cIt\u2019s like watching a decade of biology in just a couple of years.\u201d<\/p>\n<p class=\"partner-content-title\">PARTNER CONTENT<\/p>\n<p>                <a href=\"https:\/\/sandiegomagazine.com\/partner-content\/bebemos\/joven-golden-hour-tour-with-bebemos-happy-half-hour\/?utm_source=internal&amp;utm_medium=internal_link&amp;utm_campaign=partner_embed\" class=\"partner-post-link\" rel=\"nofollow noopener\" target=\"_blank\"><br \/>\n                    <img decoding=\"async\" src=\"https:\/\/www.europesays.com\/us\/wp-content\/uploads\/2025\/07\/bebemos-tequila-300x166.jpg.webp.webp\" alt=\"Joven Golden Hour Tour With Bebemos &amp; Happy Half Hour\" class=\"partner-post-thumbnail\" loading=\"lazy\"\/><br \/>\n                        Joven Golden Hour Tour With Bebemos &amp; Happy Half Hour<br \/>\n                <\/a><\/p>\n<p>                <a href=\"https:\/\/sandiegomagazine.com\/partner-content\/refresh-revamp-recieve-a-lot-of-compliments\/?utm_source=internal&amp;utm_medium=internal_link&amp;utm_campaign=partner_embed\" class=\"partner-post-link\" rel=\"nofollow noopener\" target=\"_blank\"><br \/>\n                    <img decoding=\"async\" src=\"https:\/\/www.europesays.com\/us\/wp-content\/uploads\/2025\/07\/AdobeStock_522376899_Edit-1-196x300.png\" alt=\"Refresh, Revamp, Recieve a Lot of Compliments\" class=\"partner-post-thumbnail\" loading=\"lazy\"\/><br \/>\n                        Refresh, Revamp, Recieve a Lot of Compliments<br \/>\n                <\/a><\/p>\n<p>All this innovation is rooted in a broader cultural ethos. In San Diego, longevity isn\u2019t a niche pursuit, it\u2019s a way of life. UCSD\u2019s community lectures on aging draw national audiences, and the <a href=\"https:\/\/gerigeropal.ucsd.edu\/research\/grc\/index.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Gerontology Research Collaborative<\/a> connects scientists and locals alike. \u201cI see so many San Diegans engaging in exercise and exploring nature, the arts, and technology,\u201d Moore says. \u201cWe\u2019re fortunate to live in a place where the weather and community make it easier to stay active and connected.\u201d<\/p>\n<p>That fortune, it turns out, extends beyond geography. In a city where discovery and daily existence continually shape one another, longevity doesn\u2019t just mean adding years to our time on Earth. It means living them with joy, intention, and the belief that our best days are still ahead.<\/p>\n","protected":false},"excerpt":{"rendered":"Early on a Saturday morning, the surf at La Jolla Cove is dotted with swimmers slicing through the&hellip;\n","protected":false},"author":3,"featured_media":311052,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5134],"tags":[1444,5229,1582,276,18473,3095,37443,3549,7264,67,586,132,5230,68,2969],"class_list":{"0":"post-311051","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-san-diego","8":"tag-1444","9":"tag-america","10":"tag-ca","11":"tag-california","12":"tag-everything-sd","13":"tag-features","14":"tag-living-design","15":"tag-san-diego","16":"tag-sandiego","17":"tag-united-states","18":"tag-united-states-of-america","19":"tag-unitedstates","20":"tag-unitedstatesofamerica","21":"tag-us","22":"tag-usa"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@us\/115390258451027482","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/posts\/311051","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/comments?post=311051"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/posts\/311051\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/media\/311052"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/media?parent=311051"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/categories?post=311051"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/us\/wp-json\/wp\/v2\/tags?post=311051"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}