{"id":762288,"date":"2026-04-29T22:18:25","date_gmt":"2026-04-29T22:18:25","guid":{"rendered":"https:\/\/www.europesays.com\/us\/762288\/"},"modified":"2026-04-29T22:18:25","modified_gmt":"2026-04-29T22:18:25","slug":"engineering-tough-blood-clots-for-rapid-haemostasis-and-enhanced-regeneration","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/us\/762288\/","title":{"rendered":"Engineering tough blood clots for rapid haemostasis and enhanced regeneration"},"content":{"rendered":"
  • \n

    Guo, B., Dong, R., Liang, Y. & Li, M. Haemostatic materials for wound healing applications. Nat. Rev. Chem. 5<\/b>, 773\u2013791 (2021).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Weisel, J. W. Enigmas of blood clot elasticity. Science 320<\/b>, 456\u2013457 (2008).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Jiang, S., Liu, S., Lau, S. & Li, J. Hemostatic biomaterials to halt non-compressible hemorrhage. J. Mater. Chem. B 10<\/b>, 7239\u20137259 (2022).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Bao, G. et al. Liquid-infused microstructured bioadhesives halt non-compressible hemorrhage. Nat. Commun. 13<\/b>, 5035 (2022).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Yuk, H. et al. Rapid and coagulation-independent haemostatic sealing by a paste inspired by barnacle glue. Nat. Biomed. Eng. 5<\/b>, 1131\u20131142 (2021).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Ovsianikov, A., Khademhosseini, A. & Mironov, V. The synergy of scaffold-based and scaffold-free tissue engineering strategies. Trends Biotechnol. 36<\/b>, 348\u2013357 (2018).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Lancaster, M. A. & Knoblich, J. A. Organogenesis in a dish: modeling development and disease using organoid technologies. Science 345<\/b>, 1247125 (2014).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Brandenberg, N. et al. High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays. Nat. Biomed. Eng. 4<\/b>, 863\u2013874 (2020).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Stevens, A. J. et al. Programming multicellular assembly with synthetic cell adhesion molecules. Nature 614<\/b>, 144\u2013152 (2023).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Burdis, R. & Kelly, D. J. Biofabrication and bioprinting using cellular aggregates, microtissues and organoids for the engineering of musculoskeletal tissues. Acta Biomater. 126<\/b>, 1\u201314 (2021).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Weisel, J. W. & Litvinov, R. I. Red blood cells: the forgotten player in hemostasis and thrombosis. J. Thromb. Haemost. 17<\/b>, 271\u2013282 (2019).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Garyfallogiannis, K. et al. Fracture toughness of fibrin gels as a function of protein volume fraction: mechanical origins. Acta Biomater. 159<\/b>, 49\u201362 (2023).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Tutwiler, V. et al. Rupture of blood clots: mechanics and pathophysiology. Sci. Adv. 6<\/b>, eabc0496 (2020).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Chan, K. Y. T. et al. The adhesion of clots in wounds contributes to hemostasis and can be enhanced by coagulation factor XIII. Sci. Rep. 10<\/b>, 20116 (2020).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Hickman, D. A., Pawlowski, C. L., Sekhon, U. D. S., Marks, J. & Gupta, A. S. Biomaterials and advanced technologies for hemostatic management of bleeding. Adv. Mater. 30<\/b>, 1700859 (2018).<\/p>\n

    Article<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Klein, M. K. et al. Development of optimized tissue-factor-targeted peptide amphiphile nanofibers to slow noncompressible torso hemorrhage. ACS Nano 14<\/b>, 6649\u20136662 (2020).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Schell, H. et al. The haematoma and its role in bone healing. J. Exp. Orthop. 4<\/b>, 5 (2017).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Shaikh, M. S., Zafar, M. S., Pisani, F., Lone, M. A. & Malik, Y. R. Critical features of periodontal flaps with regard to blood clot stability: a review. J. Oral Biosci. 63<\/b>, 111\u2013119 (2021).<\/p>\n

    Article<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    da Silva Santos, S. C. N., Sigurjonsson, \u00d3. E., de Almeida Cust\u00f3dio, C. & da Luz Mano, J. F. C. Blood plasma derivatives for tissue engineering and regenerative medicine therapies. Tissue Eng. Part B Rev. 24<\/b>, 454\u2013462 (2018).<\/p>\n

    Article<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Gong, J. P., Katsuyama, Y., Kurokawa, T. & Osada, Y. Double-network hydrogels with extremely high mechanical strength. Adv. Mater. 15<\/b>, 1155\u20131158 (2003).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Sun, J.-Y. et al. Highly stretchable and tough hydrogels. Nature 489<\/b>, 133\u2013136 (2012).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Zhao, X. et al. Soft materials by design: unconventional polymer networks give extreme properties. Chem. Rev. 121<\/b>, 4309\u20134372 (2021).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Liu, W., Carlisle, C. R., Sparks, E. A. & Guthold, M. The mechanical properties of single fibrin fibers. J. Thromb. Haemost. 8<\/b>, 1030\u20131036 (2010).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Lam, W. A. et al. Mechanics and contraction dynamics of single platelets and implications for clot stiffening. Nat. Mater. 10<\/b>, 61\u201366 (2011).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Malette, W. G., Quigley, H. J., Gaines, R. D., Johnson, N. D. & Rainer, W. G. Chitosan: a new hemostatic. Ann. Thorac. Surg. 36<\/b>, 55\u201358 (1983).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Dowling, M. B. et al. A self-assembling hydrophobically modified chitosan capable of reversible hemostatic action. Biomaterials 32<\/b>, 3351\u20133357 (2011).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Kim, K. et al. Coagulopathy-independent, bioinspired hemostatic materials: a full research story from preclinical models to a human clinical trial. Sci. Adv. 7<\/b>, eabc9992 (2021).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Jin, Z. et al. Gluing blood into gel by electrostatic interaction using a water-soluble polymer as an embolic agent. Proc. Natl. Acad. Sci. USA 119<\/b>, e2206685119 (2022).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Lee, K. Y., Kong, H. J., Larson, R. G. & Mooney, D. J. Hydrogel formation via cell crosslinking. Adv. Mater. 15<\/b>, 1828\u20131832 (2003).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Oliveira, B. L., Guo, Z. & Bernardes, G. J. L. Inverse electron demand Diels-Alder reactions in chemical biology. Chem. Soc. Rev. 46<\/b>, 4895\u20134950 (2017).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Darko, A. et al. Conformationally strained trans-cyclooctene with improved stability and excellent reactivity in tetrazine ligation. Chem. Sci. 5<\/b>, 3770\u20133776 (2014).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Tomarchio, E. G. et al. Tetrazine\u2013trans-cyclooctene ligation: unveiling the chemistry and applications within the human body. Bioorg. Chem. 150<\/b>, 107573 (2024).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Koo, H. et al. Bioorthogonal click chemistry-based synthetic cell glue. Small 11<\/b>, 6458\u20136466 (2015).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Pol, M. et al. Dynamic modulation of matrix adhesiveness induces epithelial-to-mesenchymal transition in prostate cancer cells in 3D. Biomaterials 299<\/b>, 122180 (2023).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Oneto, J. M. M., Khan, I., Seebald, L. & Royzen, M. In vivo bioorthogonal chemistry enables local hydrogel and systemic pro-drug to treat soft tissue sarcoma. ACS Cent. Sci. 2<\/b>, 476\u2013482 (2016).<\/p>\n

    Article<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Lux, S. E. IV. Anatomy of the red cell membrane skeleton: unanswered questions. Blood 127<\/b>, 187\u2013199 (2016).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Hoffman, J. F. Biconcave shape of human red-blood-cell ghosts relies on density differences between the rim and dimple of the ghost\u2019s plasma membrane. Proc. Natl. Acad. Sci. USA 113<\/b>, 14847\u201314851 (2016).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Jan, K.-M. & Chien, S. Role of surface electric charge in red blood cell interactions. J. Gen. Physiol. 61<\/b>, 638\u2013654 (1973).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Liu, X., Inda, M. E., Lai, Y., Lu, T. K. & Zhao, X. Engineered living hydrogels. Adv. Mater. 34<\/b>, 2201326 (2022).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Nguyen, P. Q., Courchesne, N.-M. D., Duraj-Thatte, A., Praveschotinunt, P. & Joshi, N. S. Engineered living materials: prospects and challenges for using biological systems to direct the assembly of smart materials. Adv. Mater. 30<\/b>, 1704847 (2018).<\/p>\n

    Article<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Liu, A. P. et al. The living interface between synthetic biology and biomaterial design. Nat. Mater. 21<\/b>, 390\u2013397 (2022).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Ducrot, E., Chen, Y., Bulters, M., Sijbesma, R. P. & Creton, C. Toughening elastomers with sacrificial bonds and watching them break. Science 344<\/b>, 186\u2013189 (2014).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Zhan, H., de Jong, H. & L\u00f6wik, D. W. P. M. Comparison of bioorthogonally cross-linked hydrogels for in situ cell encapsulation. ACS Appl. Bio Mater. 2<\/b>, 2862\u20132871 (2019).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Shazeeb, M. S. et al. Assessment of in vivo degradation profiles of hyaluronic acid hydrogels using temporal evolution of chemical exchange saturation transfer (CEST) MRI. Biomaterials 178<\/b>, 326\u2013338 (2018).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Mikutis, S. & Bernardes, G. J. L. SnapShot: clinical and preclinical utility of click chemistry. Cell 186<\/b>, 662\u2013662.e1 (2023).<\/p>\n

    Article<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Sun, X. et al. Surface-engineering of red blood cells as artificial antigen presenting cells promising for cancer immunotherapy. Small 13<\/b>, 1701864 (2017).<\/p>\n

    Article<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Maharjan, S. et al. Symbiotic photosynthetic oxygenation within 3D-bioprinted vascularized tissues. Matter 4<\/b>, 217\u2013240 (2021).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Ogden, R. W. & Roxburgh, D. G. A pseudo-elastic model for the Mullins effect in filled rubber. Proc. Math. Phys. Eng. Sci. 455<\/b>, 2861\u20132877 (1999).<\/p>\n

    Article<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Yang, Z., Ma, Z., Liu, S. & Li, J. Tissue adhesion with tough hydrogels: experiments and modeling. Mech. Mater. 157<\/b>, 103800 (2021).<\/p>\n

    Article<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Qi, Y., Caillard, J. & Long, R. Fracture toughness of soft materials with rate-independent hysteresis. J. Mech. Phys. Solids 118<\/b>, 341\u2013364 (2018).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Zhang, T., Lin, S., Yuk, H. & Zhao, X. Predicting fracture energies and crack-tip fields of soft tough materials. Extreme Mech. Lett. 4<\/b>, 1\u20138 (2015).<\/p>\n

    Article<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Hui, C. Y., Ruina, A., Long, R. & Jagota, A. Cohesive zone models and fracture. J. Adhes. 87<\/b>, 1\u201352 (2011).<\/p>\n

    Article<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Yuk, H. et al. Dry double-sided tape for adhesion of wet tissues and devices. Nature 575<\/b>, 169\u2013174 (2019).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Chen, X., Yuk, H., Wu, J., Nabzdyk, C. S. & Zhao, X. Instant tough bioadhesive with triggerable benign detachment. Proc. Natl Acad. Sci. USA 117<\/b>, 15497\u201315503 (2020).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     CAS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
    \n Google Scholar<\/a>\u00a0\n <\/p>\n<\/li>\n

  • \n

    Nagahama, K., Kimura, Y. & Takemoto, A. Living functional hydrogels generated by bioorthogonal cross-linking reactions of azide-modified cells with alkyne-modified polymers. Nat. Commun. 9<\/b>, 2195 (2018).<\/p>\n

    Article<\/a>\u00a0
    \n     ADS<\/a>\u00a0
    \n     PubMed<\/a>\u00a0
    \n     PubMed Central<\/a>\u00a0
    \n
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